Cas no 1082554-72-0 (3-Amino-1-(3,4-dimethylphenyl)propan-1-ol)

3-Amino-1-(3,4-dimethylphenyl)propan-1-ol is a chiral amino alcohol derivative featuring a 3,4-dimethylphenyl group and a primary amine functionality. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and fine chemicals. Its structural characteristics, including the aromatic dimethyl substitution and the hydroxyl-amine moiety, make it valuable for asymmetric synthesis and ligand design. The presence of both amino and hydroxyl groups allows for further functionalization, enabling applications in catalysis and medicinal chemistry. High purity grades are available to meet rigorous research and industrial requirements, ensuring reproducibility in synthetic workflows. Its stability and well-defined reactivity profile enhance its utility in complex molecular constructions.
3-Amino-1-(3,4-dimethylphenyl)propan-1-ol structure
1082554-72-0 structure
Product Name:3-Amino-1-(3,4-dimethylphenyl)propan-1-ol
CAS No:1082554-72-0
MF:C11H17NO
MW:179.258783102036
MDL:MFCD11581644
CID:4775139
PubChem ID:55269426
Update Time:2025-11-02

3-Amino-1-(3,4-dimethylphenyl)propan-1-ol Chemical and Physical Properties

Names and Identifiers

    • 3-amino-1-(3,4-dimethylphenyl)propan-1-ol
    • 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol
    • MDL: MFCD11581644
    • Inchi: 1S/C11H17NO/c1-8-3-4-10(7-9(8)2)11(13)5-6-12/h3-4,7,11,13H,5-6,12H2,1-2H3
    • InChI Key: JLRRDNIICOHCPX-UHFFFAOYSA-N
    • SMILES: OC(CCN)C1C=CC(C)=C(C)C=1

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 149
  • XLogP3: 1.2
  • Topological Polar Surface Area: 46.2

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3-Amino-1-(3,4-dimethylphenyl)propan-1-ol Related Literature

Additional information on 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol

Comprehensive Guide to 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol (CAS No. 1082554-72-0): Properties, Applications, and Market Insights

3-Amino-1-(3,4-dimethylphenyl)propan-1-ol (CAS No. 1082554-72-0) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This amino alcohol derivative features a unique molecular structure, combining an aromatic 3,4-dimethylphenyl group with a propanolamine backbone. Its versatility in synthesis and potential applications make it a valuable intermediate in modern chemistry.

The compound's molecular formula is C11H17NO, with a molecular weight of 179.26 g/mol. Researchers particularly value its chiral center, which makes it useful in asymmetric synthesis and drug development. The presence of both amino and hydroxyl functional groups allows for diverse chemical modifications, enabling the creation of various derivatives with tailored properties.

In pharmaceutical applications, 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol serves as a key building block for CNS-active compounds. Recent studies have explored its potential in developing novel neuromodulators and receptor-targeting agents, particularly in addressing neurological conditions that are currently trending in medical research. The compound's structural features resemble those found in several FDA-approved drugs, making it particularly interesting for drug discovery programs.

The synthesis of 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol typically involves reductive amination of the corresponding ketone or through Grignard reactions with appropriate protecting groups. Process optimization has become a hot topic in organic chemistry forums, with researchers sharing innovative approaches to improve yield and enantioselectivity. These discussions often appear in search queries related to amino alcohol synthesis and chiral building blocks.

From a commercial perspective, the demand for 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol has shown steady growth, particularly from contract research organizations and pharmaceutical developers. Market analysis reveals increasing interest in this compound as part of the broader trend toward specialty chemicals and custom synthesis services. Suppliers often highlight its availability in various purity grades, including research-grade and GMP-standard materials.

Quality control of CAS 1082554-72-0 typically involves advanced analytical techniques. HPLC methods with chiral stationary phases are commonly employed to determine enantiomeric purity, while mass spectrometry and NMR spectroscopy confirm structural identity. These analytical aspects frequently appear in scientific literature and patent applications, reflecting the compound's importance in precision chemistry.

Storage and handling recommendations for 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol emphasize protection from moisture and oxidation. The compound is generally stable under inert atmospheres at controlled temperatures, making it suitable for long-term storage when proper precautions are observed. These practical considerations often form part of frequently asked questions in chemical procurement discussions.

Recent patent literature reveals growing intellectual property activity surrounding derivatives of 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol, particularly in areas of medicinal chemistry and material science. This trend aligns with broader industry movements toward value-added intermediates and functional materials. The compound's adaptability to various chemical transformations makes it attractive for proprietary developments.

Environmental and regulatory aspects of CAS 1082554-72-0 have been evaluated according to standard protocols. While not classified as hazardous under current regulations, proper laboratory practices should always be followed when handling this or any chemical substance. These safety considerations frequently appear in workplace safety searches and chemical compliance queries.

The future outlook for 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol appears promising, with potential expansions into new application areas. Emerging research in bioconjugation chemistry and targeted drug delivery systems may create additional demand for this versatile building block. Its combination of aromatic and aliphatic characteristics offers unique opportunities for molecular design in cutting-edge research areas.

For researchers working with amino alcohol compounds, understanding the properties and potential of 3-Amino-1-(3,4-dimethylphenyl)propan-1-ol can open new avenues in synthetic chemistry. The compound's balanced hydrophilicity and lipophilicity, combined with its synthetic flexibility, make it particularly valuable in modern chemical development projects that require precise molecular control.

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