• 1. Emerging investigator series: kinetics of diopside reactivity for carbon mineralization in mafic–ultramafic rocks
  BrianaAguila,LandonHardee,H.ToddSchaef,SiavashZare,MohammadJavadAbdolhosseiniQomi,JarrodV.Crum,JadeE.HollimanJr.,ElenaTajueloRodriguez,LawrenceM.Anovitz,KevinM.Rosso,QuinR.S.Miller
• 2. Excited state potential energy surfaces and their interactions in FeIVO active sites
  Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
• 3. Fe3O4/PEG-SO3H as a heterogeneous and magnetically-recyclable nanocatalyst for the oxidation of sulfides to sulfones or sulfoxides
  Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761
• 4. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 5. Estimation of hydrogen sulfide from crude petroleum: a unique invention using a simple chemosensor?
  Shampa Kundu,Prithidipa Sahoo New J. Chem., 2019,43, 12369-12374

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Hydroxyindoles

Comprehensive Analysis of 4-Cyano-6-hydroxy (1H)Indole (CAS No. 1082040-53-6): Properties, Applications, and Research Insights

4-Cyano-6-hydroxy (1H)Indole (CAS No. 1082040-53-6) is a specialized heterocyclic compound that has garnered significant attention in pharmaceutical and biochemical research due to its unique structural features. The presence of both cyano and hydroxy functional groups on the indole backbone makes it a versatile intermediate for synthesizing bioactive molecules. Researchers often explore its potential in drug discovery, particularly for targeting enzyme inhibition and receptor modulation. Its molecular formula, C₉H₆N₂O, and precise weight of 158.16 g/mol further highlight its relevance in precision chemistry.

In recent years, the demand for indole derivatives like 4-Cyano-6-hydroxy (1H)Indole has surged, driven by their applications in cancer research and neurodegenerative disease studies. A growing body of literature suggests its role in modulating oxidative stress pathways, a hot topic in anti-aging research. The compound’s ability to interact with cellular redox systems aligns with current trends in nutraceutical development, where natural and synthetic analogs are investigated for health benefits. Users frequently search for terms like "indole-based therapeutics" or "CAS 1082040-53-6 supplier," reflecting its commercial and academic value.

The synthesis of 4-Cyano-6-hydroxy (1H)Indole typically involves multi-step organic reactions, including cyclization and functional group interconversion. Advanced techniques like HPLC purification ensure high purity (>98%), critical for in vitro assays. Its solubility profile—moderate in polar solvents like DMSO but limited in water—makes it suitable for high-throughput screening platforms. These properties are often queried in search engines, with phrases such as "how to dissolve 4-Cyano-6-hydroxy indole" or "stability of CAS 1082040-53-6."

From a commercial perspective, 4-Cyano-6-hydroxy (1H)Indole is listed by specialty chemical suppliers as a research-grade reagent, with pricing influenced by scale and purity. The compound’s niche applications in fluorescence labeling and proteomics have also been explored, tying into broader interests in biomarker detection. SEO-optimized content around these keywords—such as "buy 4-Cyano-6-hydroxy indole for lab use"—can enhance visibility for vendors and educators alike.

Ongoing studies investigate the structure-activity relationship (SAR) of 4-Cyano-6-hydroxy (1H)Indole derivatives, particularly their affinity for kinase targets. This aligns with the rise of personalized medicine, where tailored small molecules are designed for specific patient cohorts. Discussions on forums and academic platforms often highlight its potential in immune modulation, another trending topic in post-pandemic research.

In summary, 4-Cyano-6-hydroxy (1H)Indole (CAS No. 1082040-53-6) represents a critical building block in modern medicinal chemistry. Its dual functionality, coupled with emerging applications in biotechnology and material science, ensures its continued relevance. For researchers seeking reliable data, understanding its spectroscopic properties (e.g., NMR peaks at 7.2–7.8 ppm for aromatic protons) and handling precautions (storage at ?20°C) is essential. This compound exemplifies the intersection of innovation and practicality in chemical sciences.

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