Cas no 108-55-4 (oxane-2,6-dione)
oxane-2,6-dione Chemical and Physical Properties
Names and Identifiers
-
- Dihydro-2H-pyran-2,6(3H)-dione
- Tetrahydropyran-2,6-dione
- Glutaric anhydride
- oxane-2,6-dione
- ?HX-109
- GAN
- pyroglutaricacid
- Glutaric anhydrid
- Glutamic Anhydride
- glutaricacidanhydride
- pentanedioicanhydride
- Glutaric anhydride,90%
- Glutaric anhydride,95%
- Pentanedioic anhydride
- Glutaric acid anhydride
- Pyroglutaric acid
- 2H-Pyran-2,6(3H)-dione, dihydro-
- Pentanedioic acid anhydride
- Anhydrid kyseliny glutarove
- Anhydrid kyseliny glutarove [Czech]
- Glutaric anhydride, 95%
- VANNPISTIUFMLH-UHFFFAOYSA-N
- 63OFI15S80
- NSC16640
- 3H-4,5-dihydropyran-2,6-dione
- WLN: T6VOVT
- WLN: T6VOVTJ
- dihydro-pyran-2,
- dihydro-3H-pyran-2,6-dione
- dihydro-pyran-2,6
- NCGC00248238-01
- EN300-18018
- Oxacyclohexane-2,6-dione
- InChI=1/C5H6O3/c6-4-2-1-3-5(7)8-4/h1-3H
- CHEMBL3188341
- A801892
- DTXCID3024362
- FT-0626733
- UNII-63OFI15S80
- NCGC00254877-01
- DTXSID5044362
- AS-13081
- SCHEMBL19926
- NS00008715
- CAS-108-55-4
- AKOS000121028
- BP-13001
- Glutaric anhydride, technical, >=90% (NT)
- AI3-06352
- CHEBI:167482
- 5-17-11-00009 (Beilstein Handbook Reference)
- Glutaric anhydride, Vetec(TM) reagent grade, 94%
- BRN 0110051
- Q-201164
- PENTAHYDROPYRAN-2,6-DIONE
- G0071
- 1219794-53-2
- NSC 16640
- 2H-Pyran-2, dihydro-
- dihydro-pyran-2,6-dione
- pentanedioic-d6 anhydride
- Q11074437
- tetrahydropyran-2,6-dione;dihydro-2H-pyran-2,6(3H)-dione
- EINECS 203-593-6
- 2H-Pyran-2,6(3H)-dione, dihydro
- 108-55-4
- EC 203-593-6
- DIHYDROPYRAN-2,6-DIONE
- F0001-0173
- NSC-16640
- MFCD00006679
- Tox21_300975
- AM1000009
- 2HPyran2,6(3H)dione, dihydro
- Dihydro2Hpyran2,6(3H)dione
- STK397450
- 203-593-6
- FG14622
-
- MDL: MFCD00006679
- Inchi: 1S/C5H6O3/c6-4-2-1-3-5(7)8-4/h1-3H2
- InChI Key: VANNPISTIUFMLH-UHFFFAOYSA-N
- SMILES: O1C(CCCC1=O)=O
- BRN: 0110051
Computed Properties
- Exact Mass: 114.03200
- Monoisotopic Mass: 114.032
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 8
- Rotatable Bond Count: 0
- Complexity: 114
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 3
- XLogP3: -0.1
- Topological Polar Surface Area: 43.4
Experimental Properties
- Color/Form: Acicular crystal
- Density: 1.411
- Melting Point: 55.0 to 58.0 deg-C
- Boiling Point: 150?°C/10?mmHg(lit.)
- Flash Point: Fahrenheit: 343.4 ° f < br / > Celsius: 173 ° C < br / >
- Refractive Index: 1.4630 (estimate)
- Water Partition Coefficient: hydrolysis
- PSA: 43.37000
- LogP: 0.24010
- Sensitiveness: Moisture Sensitive
- FEMA: 3273
- Solubility: Soluble in ether, ethanol and tetrahydrofuran
oxane-2,6-dione Security Information
-
Symbol:
- Prompt:warning
- Signal Word:Danger
- Hazard Statement: H302,H312,H315,H318,H335
- Warning Statement: P261,P280,P305+P351+P338
- Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Hazard Category Code: 21/22-37/38-41
- Safety Instruction: S26-S36/39-S36/37/39
- FLUKA BRAND F CODES:2-21
- RTECS:MA3850000
-
Hazardous Material Identification:
- HazardClass:8
- PackingGroup:Ⅲ
- TSCA:Yes
- Storage Condition:Store at room temperature
- Safety Term:S26;S36/37/39
- Risk Phrases:R21/22; R36/37/38
oxane-2,6-dione Customs Data
- HS CODE:2917190090
- Customs Data:
China Customs Code:
2917190090Overview:
2917190090 Other acyclic polycarboxylic acids. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to, Terephthalic acid please specify4-CBAvalue, Terephthalic acid please specifyP-TLacid value, Terephthalic acid please indicate color, Terephthalic acid please indicate moisture
Summary:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
oxane-2,6-dione Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A119001098-1000g |
Dihydro-2H-pyran-2,6(3H)-dione |
108-55-4 | 97% | 1000g |
$164.32 | 2023-09-04 | |
| Fluorochem | 044731-25g |
Glutaric Anhydride |
108-55-4 | 97% | 25g |
£16.00 | 2022-03-01 | |
| Fluorochem | 044731-100g |
Glutaric Anhydride |
108-55-4 | 97% | 100g |
£43.00 | 2022-03-01 | |
| Fluorochem | 044731-500g |
Glutaric Anhydride |
108-55-4 | 97% | 500g |
£125.00 | 2022-03-01 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | WG6567-100g |
oxane-2,6-dione |
108-55-4 | ≥99% | 100g |
¥190元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | WG6567-25g |
oxane-2,6-dione |
108-55-4 | ≥99% | 25g |
¥85元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | WG6567-500g |
oxane-2,6-dione |
108-55-4 | ≥99% | 500g |
¥580元 | 2023-09-15 | |
| Fluorochem | 044731-1g |
Glutaric Anhydride |
108-55-4 | 97% | 1g |
£11.00 | 2022-03-01 | |
| SHANG HAI XIANG HUI YI YAO Technology Co., Ltd. | CB20825-1g |
oxane-2,6-dione |
108-55-4 | 97% | 1g |
0.00 | 2021-07-09 | |
| SHANG HAI XIANG HUI YI YAO Technology Co., Ltd. | CB20825-100g |
oxane-2,6-dione |
108-55-4 | 97% | 100g |
64.00 | 2021-07-09 |
oxane-2,6-dione Suppliers
oxane-2,6-dione Related Literature
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Yuxin Yao,Lijuan Gui,Beike Gao,Zhenwei Yuan,Yisha Chen,Chen Wei,Qing He,Fei Wang,Mingjun Xu,Haiyan Chen New J. Chem. 2019 43 1785
-
Hongguang Li,Chi-Fai Chan,Wai-Lun Chan,Sam Lear,Steven L. Cobb,Nai-Ki Mak,Terrence Chi-Kong Lau,Rongfeng Lan,Wai-Kwok Wong,Ka-Leung Wong Org. Biomol. Chem. 2014 12 5876
-
Hongjiang Wang,Zebiao Li,Xiaoxia Yu,Ruidong Chen,Xiulai Chen,Liming Liu RSC Adv. 2015 5 75160
-
Emily R. Draper,Laura L. E. Mears,Ana M. Castilla,Stephen M. King,Tom O. McDonald,Riaz Akhtar,Dave J. Adams RSC Adv. 2015 5 95369
-
Kai Yu,Philip Taynton,Wei Zhang,Martin L. Dunn,H. Jerry Qi RSC Adv. 2014 4 48682
Additional information on oxane-2,6-dione
Chemical Profile of Oxane-2,6-dione (CAS No: 108-55-4)
Oxane-2,6-dione, also identified by its Chemical Abstracts Service Number (CAS No) 108-55-4, is a significant heterocyclic compound with a molecular structure that has garnered considerable attention in the field of organic chemistry and pharmaceutical research. This compound belongs to the dioxane family, characterized by a six-membered ring containing two oxygen atoms. The presence of two ketone functional groups at the 2 and 6 positions imparts unique reactivity and makes it a valuable intermediate in synthetic chemistry.
The molecular formula of oxane-2,6-dione is C?H?O?, reflecting its composition of four carbon atoms, four hydrogen atoms, and three oxygen atoms. Its systematic name underscores its structural features, highlighting the dioxane core with ketone substituents. The compound is typically encountered as a colorless to pale yellow liquid with a characteristic odor, exhibiting moderate solubility in polar organic solvents such as ethanol and dimethyl sulfoxide (DMSO).
The synthesis of oxane-2,6-dione has been extensively studied due to its utility in various chemical transformations. One common synthetic route involves the oxidation of dihydric alcohols derived from dioxane precursors. Recent advancements in catalytic methods have improved the efficiency and selectivity of these reactions, enabling the production of high-purity oxane-2,6-dione under milder conditions. These innovations are particularly relevant in industrial applications where cost-effectiveness and environmental considerations are paramount.
Recent research has highlighted the role of oxane-2,6-dione as a versatile building block in medicinal chemistry. Its rigid dioxane ring system provides a stable scaffold for further functionalization, making it an attractive candidate for designing novel bioactive molecules. For instance, studies have demonstrated its incorporation into heterocyclic frameworks that exhibit antimicrobial and anti-inflammatory properties. The ability to modify the substituents at the 2 and 6 positions allows for fine-tuning of pharmacological activity, opening avenues for drug discovery efforts.
The reactivity of oxane-2,6-dione is further underscored by its participation in various organic transformations. It serves as a precursor in the synthesis of more complex molecules through reactions such as Michael additions, aldol condensations, and cyclizations. These reactions are pivotal in constructing intricate molecular architectures that are essential for developing new therapeutic agents. The compound's ability to undergo selective functionalization has made it a preferred choice for synthetic chemists seeking efficient pathways to target molecules.
In the realm of materials science, oxane-2,6-dione has been explored for its potential applications in polymer chemistry. Its incorporation into polymer backbones can enhance material properties such as thermal stability and mechanical strength. Researchers have investigated its use in creating cross-linked networks with tailored characteristics for applications ranging from coatings to advanced composites. The adaptability of oxane-2,6-dione in this context underscores its broad utility beyond traditional pharmaceutical applications.
The pharmacological potential of derivatives of oxane-2,6-dione has been a focal point in recent studies. Researchers have synthesized analogs with modified functional groups to evaluate their biological activity across different disease models. Preliminary findings suggest that certain derivatives exhibit promising effects on enzymes and receptors involved in metabolic disorders and neurodegenerative diseases. These discoveries highlight the importance of oxane-2,6-dione as a scaffold for developing next-generation therapeutics.
From an industrial perspective, the demand for high-purity oxane-2,6-dione has driven advancements in purification technologies. Techniques such as distillation under reduced pressure and recrystallization from appropriate solvents have been optimized to ensure product integrity. These methods are crucial for meeting the stringent requirements of pharmaceutical manufacturers who rely on consistent quality for their formulations.
The environmental impact of synthesizing and handling oxane-2,6-dione has also been a subject of investigation. Efforts have been directed toward developing greener synthetic routes that minimize waste generation and reduce energy consumption. For instance, biocatalytic approaches using engineered enzymes have shown promise in facilitating the conversion of renewable feedstocks into oxane-2,6-dione derivatives without compromising yield or selectivity.
In conclusion, oxane-2,6-dione (CAS No: 108-55-4) stands out as a multifaceted compound with significant implications across multiple scientific disciplines. Its unique structural features enable diverse applications in pharmaceuticals, materials science, and organic synthesis. As research continues to uncover new methodologies for its production and utilization, oxane-2,6-dione is poised to remain at the forefront of chemical innovation.
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