• 1. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 2. Excess electrons in lithium–ethylamine solutions—density, electrical conductivity and EPR studies
  Phys. Chem. Chem. Phys., 1999,1, 3561-3565
• 3. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 4. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 5. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives m-Xylenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Xylenes m-Xylenes

The Compound CAS No. 1078627-79-8: (2,4-Dimethylphenyl)Methanesulfonamide

(2,4-Dimethylphenyl)methanesulfonamide, identified by the CAS registry number 1078627-79-8, is a versatile organic compound with significant applications in various fields. This compound belongs to the class of sulfonamides, which are widely used in pharmaceuticals, agrochemicals, and specialty chemicals. The structure of this compound consists of a methanesulfonamide group attached to a 2,4-dimethylphenyl ring, which imparts unique chemical and physical properties.

Recent studies have highlighted the importance of sulfonamides like (2,4-Dimethylphenyl)methanesulfonamide in drug discovery and development. The methanesulfonamide group is known for its ability to act as a bioisostere of carboxylic acids, making it a valuable substituent in medicinal chemistry. This property has led to its use in designing potential inhibitors for various enzymes and receptors. For instance, researchers have explored its role in targeting kinases and other protein kinases involved in cancer pathways.

The synthesis of (2,4-Dimethylphenyl)methanesulfonamide typically involves nucleophilic substitution reactions or coupling methods. Recent advancements in catalytic systems have enabled more efficient and environmentally friendly production processes. For example, the use of palladium catalysts in coupling reactions has significantly improved the yield and purity of this compound. These developments are crucial for scaling up production to meet the growing demand in pharmaceutical and agrochemical industries.

In terms of applications, (2,4-Dimethylphenyl)methanesulfonamide has shown promise as an intermediate in the synthesis of bioactive molecules. Its ability to undergo various transformations makes it a valuable building block for constructing complex structures. For instance, it can be used as a starting material for synthesizing herbicides with improved selectivity and efficacy. Recent studies have demonstrated its role in developing next-generation herbicides that target specific metabolic pathways in weeds without affecting crops.

The physical properties of this compound are also worth noting. It has a melting point of approximately 155°C and is soluble in common organic solvents such as dichloromethane and acetonitrile. These properties make it suitable for use in various chemical reactions and formulations. Additionally, its stability under physiological conditions makes it a potential candidate for drug delivery systems.

From an environmental perspective, understanding the fate and behavior of (2,4-Dimethylphenyl)methanesulfonamide is essential for assessing its impact on ecosystems. Recent toxicological studies have shown that this compound exhibits low acute toxicity to aquatic organisms when used at recommended application rates. However, further research is needed to evaluate its long-term effects on non-target species and soil microbiota.

In conclusion, (2,4-Dimethylphenyl)methanesulfonamide (CAS No. 1078627-79-8) is a multifaceted compound with significant potential in pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure and versatile reactivity make it an invaluable tool for researchers and industry professionals alike. As new applications continue to emerge, further studies are required to fully harness its potential while ensuring its safe use and environmental compatibility.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)