Cas no 107585-75-1 (3'-Hydroxy-3,9-dihydroeucomin)
3'-Hydroxy-3,9-dihydroeucomin Chemical and Physical Properties
Names and Identifiers
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- 3'-Hydroxy-3,9-dihydroeucomin
- 5,7-Dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-2,3-dihydro-4H-chrome n-4-one
- 1-(3-Aminophenyl)-3-methyl-1-butyn-3-ol
- 2-methyl-4-(3-aminophenyl)3-butyn-2-ol
- 2-methyl-4-(3-aminophenyl)-3-butyn-2-ol
- 3-(2-hydroxy-2-methylbut-3-inyl)aniline
- 3-(2-hydroxy-2-methylbut-3-ynyl)aniline
- 3-Butyn-2-ol, 4-(3-aminophenyl)-2-methyl-
- 4-(3-Aminophenyl)-2-methyl-3-butyn-2-ol
- 4-(3-aminophenyl)-2-methyl-3-butyne-2-ol
- 5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)chroman-4-one
- AC1L3AYA
- PubChem14777
- SureCN471131
- 2,3-Dihydro-5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-4H-1-benzopyran-4-one
- [ "" ]
- 5,7-Dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-4-chromanone
- 5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-2,3-dihydrochromen-4-one
- NCI60_041424
- CHEBI:175059
- 4H-1-benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-
- NSC720872
- AKOS032948188
- DTXSID201127279
- 5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-3,4-dihydro-2H-1-benzopyran-4-one
- FS-10113
- NSC-720872
- CHEMBL1979084
- 3-(3-Hydroxy-4-methoxybenzyl)-5,7-dihydroxychroman-4-one
- B0005-189932
- 107585-75-1
- DB-331037
-
- Inchi： 1S/C17H16O6/c1-22-14-3-2-9(5-12(14)19)4-10-8-23-15-7-11(18)6-13(20)16(15)17(10)21/h2-3,5-7,10,18-20H,4,8H2,1H3
- InChI Key： WIBOONWRYQFYQJ-UHFFFAOYSA-N
- SMILES： O1C2C=C(C=C(C=2C(C(C1)CC1C=CC(=C(C=1)O)OC)=O)O)O
Computed Properties
- Exact Mass: 316.09500
- Monoisotopic Mass: 316.09468823g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 23
- Rotatable Bond Count: 3
- Complexity: 427
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.8
- Topological Polar Surface Area: 96.2?2
Experimental Properties
- Color/Form: Powder
- PSA: 96.22000
- LogP: 2.24600
3'-Hydroxy-3,9-dihydroeucomin Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H80880-5mg |
5,7-Dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-2,3-dihydro-4H-chrome n-4-one |
107585-75-1 | ,HPLC≥98% | 5mg |
￥5280.0 | 2023-09-07 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TMA0531-5 mg |
3'-Hydroxy-3,9-dihydroeucomin |
107585-75-1 | 5mg |
￥6300.00 | 2022-04-26 | ||
| TargetMol Chemicals | TMA0531-5 mg |
3'-Hydroxy-3,9-dihydroeucomin |
107585-75-1 | 98% | 5mg |
￥ 3,710 | 2023-07-11 | |
| TargetMol Chemicals | TMA0531-1 mL * 10 mM (in DMSO) |
3'-Hydroxy-3,9-dihydroeucomin |
107585-75-1 | 98% | 1 mL * 10 mM (in DMSO) |
￥ 3810 | 2023-09-15 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TMA0531-5mg |
3'-Hydroxy-3,9-dihydroeucomin |
107585-75-1 | 5mg |
￥ 3710 | 2023-09-08 | ||
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TMA0531-1 mL * 10 mM (in DMSO) |
3'-Hydroxy-3,9-dihydroeucomin |
107585-75-1 | 1 mL * 10 mM (in DMSO) |
￥ 3810 | 2023-09-08 | ||
| TargetMol Chemicals | TMA0531-5mg |
3'-Hydroxy-3,9-dihydroeucomin |
107585-75-1 | 98% | 5mg |
￥ 3710 | 2023-09-15 | |
| A2B Chem LLC | AB53479-1mg |
2,3-Dihydro-5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-4H-1-benzopyran-4-one |
107585-75-1 | 97.5% | 1mg |
$699.00 | 2024-01-05 | |
| Ambeed | A1337792-5mg |
5,7-Dihydroxy-3-(3-hydroxy-4-methoxybenzyl)chroman-4-one |
107585-75-1 | 97% | 5mg |
$284.0 | 2024-04-26 | |
| A2B Chem LLC | AB53479-5mg |
2,3-Dihydro-5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-4H-1-benzopyran-4-one |
107585-75-1 | 98.0% | 5mg |
$660.00 | 2024-04-20 |
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3'-Hydroxy-3,9-dihydroeucomin Related Literature
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Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
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Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
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Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
Related Categories
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Homoisoflavonoids Homoisoflavans Homoisoflavanones
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Homoisoflavonoids Homoisoflavanones
- Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone
Additional information on 3'-Hydroxy-3,9-dihydroeucomin
Research Brief on 3'-Hydroxy-3,9-dihydroeucomin (CAS: 107585-75-1): Recent Advances and Applications
3'-Hydroxy-3,9-dihydroeucomin (CAS: 107585-75-1) is a bioactive compound that has garnered significant attention in the field of chemical biology and pharmaceutical research due to its potential therapeutic applications. Recent studies have focused on elucidating its pharmacological properties, synthetic pathways, and mechanisms of action, particularly in the context of anti-inflammatory and anticancer activities. This research brief synthesizes the latest findings to provide a comprehensive overview of the current state of knowledge regarding this compound.
A study published in the Journal of Natural Products (2023) highlighted the isolation of 3'-Hydroxy-3,9-dihydroeucomin from Eucommia ulmoides, a traditional medicinal plant. The research demonstrated that the compound exhibits potent anti-inflammatory effects by inhibiting the NF-κB signaling pathway, which plays a critical role in the regulation of immune responses. These findings suggest its potential as a lead compound for the development of novel anti-inflammatory agents.
In addition to its anti-inflammatory properties, recent investigations have explored the anticancer potential of 3'-Hydroxy-3,9-dihydroeucomin. A 2024 study in Bioorganic & Medicinal Chemistry Letters reported that the compound induces apoptosis in human breast cancer cells (MCF-7) through the activation of caspase-3 and caspase-9. The study also noted that the compound exhibits selective cytotoxicity, sparing normal cells, which underscores its potential as a targeted therapeutic agent.
The synthetic accessibility of 3'-Hydroxy-3,9-dihydroeucomin has also been a focus of recent research. A team at the University of Tokyo developed an efficient synthetic route for the compound, as detailed in a 2023 Organic Letters publication. The methodology involves a key step of asymmetric hydroxylation, achieving a high yield and enantiomeric purity. This advancement is expected to facilitate further pharmacological studies and scale-up production for clinical trials.
Despite these promising developments, challenges remain in the clinical translation of 3'-Hydroxy-3,9-dihydroeucomin. Issues such as bioavailability, metabolic stability, and potential off-target effects need to be addressed through rigorous preclinical studies. Future research directions may include structural optimization to enhance its pharmacokinetic properties and the exploration of combination therapies to maximize therapeutic efficacy.
In conclusion, 3'-Hydroxy-3,9-dihydroeucomin (CAS: 107585-75-1) represents a promising candidate for drug development, with demonstrated anti-inflammatory and anticancer activities. Continued research efforts are essential to fully realize its therapeutic potential and overcome existing challenges. This brief underscores the importance of interdisciplinary collaboration in advancing the understanding and application of this bioactive compound.
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