• 1. Emerging enantiomeric resolution materials with homochiral nano-fabrications
  Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
• 2. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
• 3. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 4. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
• 5. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
  Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220

Benzene, 1-Phenoxy-2-(Trifluoromethyl) - CAS No. 106877-16-1

Benzene, 1-phenoxy-2-(trifluoromethyl), also known by its CAS number 106877-16-1, is a versatile organic compound with significant applications in various fields. This compound is characterized by its unique structure, which combines a benzene ring with a phenoxy group and a trifluoromethyl substituent. The phenoxy group (-O-C?H?) is attached at the 1-position of the benzene ring, while the trifluoromethyl (-CF?) group is located at the 2-position. This arrangement imparts distinctive electronic and steric properties to the molecule, making it highly valuable in both academic research and industrial applications.

The synthesis of benzene, 1-phenoxy-2-(trifluoromethyl) typically involves multi-step reactions, often starting from benzene derivatives and incorporating the phenoxy and trifluoromethyl groups through nucleophilic aromatic substitution or other advanced organic reactions. Recent advancements in catalytic methods have improved the efficiency and selectivity of these reactions, leading to higher yields and purer products. For instance, researchers have explored the use of palladium-catalyzed coupling reactions to construct the phenoxy group with greater precision.

One of the most notable applications of this compound is in materials science. The presence of the trifluoromethyl group introduces strong electron-withdrawing effects, which enhance the stability and reactivity of the molecule. This property makes it an excellent candidate for use in high-performance polymers and advanced materials. For example, studies have shown that incorporating benzene, 1-phenoxy-2-(trifluoromethyl) into polymer matrices can significantly improve their thermal stability and mechanical strength.

In addition to its role in materials science, this compound has also found applications in pharmaceutical research. The phenoxy group is known to exhibit bioisosteric properties, meaning it can mimic the effects of other functional groups in drug molecules. This makes benzene, 1-phenoxy-2-(trifluoromethyl) a valuable building block in drug design. Recent studies have explored its potential as a scaffold for developing new classes of antibiotics and anticancer agents.

The environmental impact of this compound has also been a topic of interest in recent years. Researchers have investigated its biodegradation pathways and toxicity profiles to ensure its safe use in industrial settings. Findings suggest that while benzene, 1-phenoxy-2-(trifluoromethyl) is not inherently toxic at low concentrations, proper handling and disposal protocols are essential to minimize environmental risks.

In conclusion, benzene, 1-phenoxy-2-(trifluoromethyl), with its CAS number 106877-16-1, stands as a prime example of how structural modifications can lead to versatile and valuable compounds. Its applications span across materials science, pharmaceuticals, and environmental chemistry, with ongoing research continually uncovering new potential uses. As technology advances and our understanding of organic chemistry deepens, this compound will undoubtedly play an even more significant role in shaping future innovations.

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