• 1. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
• 2. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 3. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 4. Establishment and implications of a characterization method for magnetic nanoparticle using cell tracking velocimetry and magnetic susceptibility modified solutions
  Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
• 5. Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
  Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389

Comprehensive Guide to 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane (CAS No. 1062555-59-2)

4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane (CAS No. 1062555-59-2) is a highly specialized boronic ester compound widely used in organic synthesis, pharmaceuticals, and materials science. This compound belongs to the dioxaborolane family, known for their stability and versatility in Suzuki-Miyaura cross-coupling reactions, a key method for forming carbon-carbon bonds in modern chemistry.

The molecular structure of 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane features a naphthalene moiety linked to a phenyl group, which is further connected to a dioxaborolane ring. This unique arrangement enhances its reactivity and makes it a valuable intermediate in the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and advanced materials.

One of the most significant applications of 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane is in the field of drug discovery. Researchers frequently utilize this compound as a building block for the development of novel therapeutic agents. Its ability to participate in palladium-catalyzed coupling reactions allows for the efficient construction of biaryl structures, which are common in many FDA-approved drugs.

In addition to pharmaceutical applications, 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane is also employed in the production of organic electronic materials. Its conjugated aromatic system makes it suitable for use in OLEDs (Organic Light-Emitting Diodes) and photovoltaic devices, where it contributes to improved charge transport properties. This aligns with the growing demand for sustainable energy solutions and green chemistry practices.

The compound's stability under various conditions is another notable feature. Unlike some boronic acids, 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane is less prone to protodeboronation, making it a preferred choice for long-term storage and handling. This characteristic is particularly important for industrial-scale applications where consistency and reliability are paramount.

Recent advancements in catalysis and synthetic methodology have further expanded the utility of 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane. For instance, its use in flow chemistry setups has enabled more efficient and scalable production processes, addressing the need for cost-effective and environmentally friendly manufacturing techniques.

From a market perspective, the demand for 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane is expected to grow steadily, driven by its applications in high-value industries such as pharmaceuticals and electronics. Companies specializing in fine chemicals and custom synthesis are increasingly offering this compound to meet the needs of research and development laboratories worldwide.

For researchers and chemists working with 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane, it is essential to follow standard safety protocols. While the compound is not classified as hazardous, proper handling, including the use of personal protective equipment (PPE) and adequate ventilation, is recommended to ensure safe laboratory practices.

In summary, 4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane (CAS No. 1062555-59-2) is a versatile and valuable compound with broad applications in organic synthesis, drug development, and material science. Its unique structural features and reactivity profile make it an indispensable tool for chemists and researchers aiming to push the boundaries of innovation in their respective fields.

• 929103-27-5(4,4,5,5-tetramethyl-2-(3-phenyl-9-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anthracen-10-yl)-1,3,2-dioxaborolane)
• 1092390-02-7(4,4,5,5-Tetramethyl-2-(4-(naphthalen-2-yl)phenyl)-1,3,2-dioxaborolane)
• 914675-52-8(4,4,5,5-tetramethyl-2-(2-phenylphenyl)-1,3,2-dioxaborolane)
• 312303-48-3(4,4,5,5-tetramethyl-2-(2-methylnaphthalen-1-yl)-1,3,2-dioxaborolane)
• 1158227-59-8(4,4,5,5-Tetramethyl-2-(4-(triphenylen-2-yl)phenyl)-1,3,2-dioxaborolane)
• 398128-09-1(2,2'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)biphenyl)
• 583823-92-1(1,3,2-DIOXABOROLANE, 4,4,5,5-TETRAMETHYL-2-[1,1':3',1''-TERPHENYL]-4'-YL-)
• 2072802-03-8(1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[5-methyl-2-(1-naphthalenyl)phenyl]-)
• 647836-56-4(1,3,2-Dioxaborolane, 2-[2,2'-binaphthalen]-6-yl-4,4,5,5-tetramethyl-)
• 612086-25-6(1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-(2-phenyl-1-naphthalenyl)-)