Cas no 1060815-57-7 ((4,6-dichloropyridin-3-yl)methanamine)

(4,6-Dichloropyridin-3-yl)methanamine is a versatile chlorinated pyridine derivative with a reactive primary amine functional group. Its molecular structure, featuring two chlorine substituents at the 4- and 6-positions, enhances its utility as a key intermediate in pharmaceutical and agrochemical synthesis. The amine group enables further derivatization, facilitating the formation of amides, imines, or other nitrogen-containing compounds. This compound exhibits high reactivity in nucleophilic substitution reactions, making it valuable for constructing complex heterocyclic frameworks. Its stability under standard conditions ensures consistent performance in synthetic applications. The dichloropyridine core also contributes to its potential as a building block for bioactive molecules, particularly in the development of herbicides and antimicrobial agents.
(4,6-dichloropyridin-3-yl)methanamine structure
1060815-57-7 structure
Product Name:(4,6-dichloropyridin-3-yl)methanamine
CAS No:1060815-57-7
MF:C6H6Cl2N2
MW:177.031239032745
MDL:MFCD13189339
CID:1170980
PubChem ID:72212306
Update Time:2025-11-04

(4,6-dichloropyridin-3-yl)methanamine Chemical and Physical Properties

Names and Identifiers

    • (4,6-dichloropyridin-3-yl)methanamine
    • AB68217
    • 1060815-57-7
    • EN300-1967965
    • MDL: MFCD13189339
    • Inchi: 1S/C6H6Cl2N2/c7-5-1-6(8)10-3-4(5)2-9/h1,3H,2,9H2
    • InChI Key: JFGSACPJTUATFY-UHFFFAOYSA-N
    • SMILES: ClC1C=C(N=CC=1CN)Cl

Computed Properties

  • Exact Mass: 175.9908036g/mol
  • Monoisotopic Mass: 175.9908036g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 110
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.3
  • Topological Polar Surface Area: 38.9?2

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Additional information on (4,6-dichloropyridin-3-yl)methanamine

Introduction to (4,6-dichloropyridin-3-yl)methanamine and Its Significance in Modern Chemical Biology

(4,6-dichloropyridin-3-yl)methanamine, with the CAS number 1060815-57-7, is a versatile intermediate compound that has garnered significant attention in the field of chemical biology and pharmaceutical research. This compound, characterized by its dichloropyridine core and an amine functional group, serves as a crucial building block in the synthesis of various bioactive molecules. Its unique structural features make it particularly valuable for the development of new drugs targeting a wide range of therapeutic areas.

The dichloropyridine moiety in (4,6-dichloropyridin-3-yl)methanamine contributes to its reactivity and adaptability in synthetic chemistry. This feature allows for further functionalization, enabling the creation of complex molecular architectures. In recent years, there has been a growing interest in exploring the potential of such heterocyclic compounds in medicinal chemistry due to their ability to interact with biological targets in sophisticated ways.

One of the most compelling aspects of (4,6-dichloropyridin-3-yl)methanamine is its role in the development of novel agrochemicals. The compound's structural framework is conducive to designing molecules that can modulate plant growth and protect crops from pests and diseases. Researchers have leveraged its properties to create innovative solutions for sustainable agriculture, addressing the increasing global demand for food production.

In addition to its applications in agrochemistry, (4,6-dichloropyridin-3-yl)methanamine has shown promise in the field of pharmaceuticals. Its ability to serve as a precursor for more complex drug molecules has made it a valuable asset in drug discovery programs. For instance, studies have demonstrated its utility in synthesizing compounds with potential antimicrobial and anti-inflammatory properties. These findings highlight the importance of (4,6-dichloropyridin-3-yl)methanamine as a key intermediate in developing next-generation therapeutics.

The synthesis of (4,6-dichloropyridin-3-yl)methanamine involves multi-step organic reactions that require precise control over reaction conditions. Advanced synthetic methodologies have been employed to optimize yield and purity, ensuring that the compound meets the stringent requirements of industrial applications. The use of catalytic processes and green chemistry principles has further enhanced the sustainability of its production.

Recent advancements in computational chemistry have also played a pivotal role in understanding the reactivity and potential applications of (4,6-dichloropyridin-3-yl)methanamine. Molecular modeling studies have provided insights into how this compound interacts with biological targets, guiding the design of more effective derivatives. These computational approaches are essential for accelerating the drug discovery process and reducing experimental costs.

The impact of (4,6-dichloropyridin-3-yl)methanamine extends beyond academic research. Industrial applications have emerged as significant markets for this compound, driven by its versatility and cost-effectiveness. Companies specializing in fine chemicals have integrated its synthesis into their production pipelines, meeting the growing demand from various sectors.

In conclusion, (4,6-dichloropyridin-3-yl)methanamine (CAS no. 1060815-57-7) is a multifaceted compound with broad applications in chemical biology and pharmaceutical research. Its unique structural properties make it an invaluable intermediate for synthesizing bioactive molecules with potential therapeutic benefits. As research continues to uncover new applications for this compound, its significance in modern chemical biology is set to grow even further.

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