• 1. Alternative mixtures to R-600a. Theoretical assessment and experimental energy evaluation of binary mixtures in a commercial cooler: Mélanges alternatifs au R-600a. évaluation théorique et évaluation énergétique expérimentale de mélanges binaires dans un refroidisseur commercial.
  DanielCalleja-Anta,DanielSánchez,LauraNebot-Andres,RamónCabello,RodrigoLlopis
• 2. An aptamer-based keypad lock system?
  Yaqing Liu,Jiangtao Ren,Jing Li,Jiyang Liu,Erkang Wang Chem. Commun., 2012,48, 802-804
• 3. An investigation of the electrochemical delithiation process of carbon coated α-Fe2O3nanoparticles
  Adrian Brandt,Florian Winter,Sebastian Klamor,Frank Berkemeier,Jatinkumar Rana,Rainer P?ttgen,Andrea Balducci J. Mater. Chem. A, 2013,1, 11229-11236
• 4. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 5. Achieving crystal-induced room temperature phosphorescence and reversible photochromic properties by strong intermolecular interactions?
  Fuming Xiao,Mengzhu Wang,Yunxiang Lei,Wenbo Dai,Yunbing Zhou,Miaochang Liu,Wenxia Gao,Xiaobo Huang,Huayue Wu J. Mater. Chem. C, 2020,8, 17410-17416

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazinanes Piperazines Piperazine carboxylic acids and derivatives

3-{4-(tert-butoxy)carbonyl-3-methylpiperazin-1-yl}propanoic acid (CAS 1060813-90-2): A Comprehensive Overview

3-{4-(tert-butoxy)carbonyl-3-methylpiperazin-1-yl}propanoic acid (CAS 1060813-90-2) is a specialized organic compound that has garnered significant attention in the pharmaceutical and chemical research communities. This compound, often referred to as a piperazine derivative, is widely utilized in the synthesis of various bioactive molecules. Its unique structural features, including the tert-butoxycarbonyl (Boc) protecting group and the 3-methylpiperazine moiety, make it a valuable intermediate in medicinal chemistry.

The CAS 1060813-90-2 compound is particularly notable for its role in the development of drug candidates targeting neurological and inflammatory diseases. Researchers are increasingly exploring its potential in the design of small molecule inhibitors and modulators of protein-protein interactions. The presence of the Boc group in the molecule ensures stability during synthetic processes, while the propanoic acid tail provides a handle for further functionalization.

One of the most frequently asked questions about 3-{4-(tert-butoxy)carbonyl-3-methylpiperazin-1-yl}propanoic acid is its solubility and stability under various conditions. This compound is typically soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM), making it suitable for a wide range of chemical reactions. Its stability at room temperature is another advantage, allowing for easy storage and handling in laboratory settings.

In recent years, the demand for CAS 1060813-90-2 has surged due to its applications in peptide synthesis and combinatorial chemistry. The compound's ability to act as a building block for more complex structures has made it indispensable in high-throughput screening and drug discovery programs. Additionally, its compatibility with solid-phase synthesis techniques has further expanded its utility in modern chemical research.

The synthesis of 3-{4-(tert-butoxy)carbonyl-3-methylpiperazin-1-yl}propanoic acid involves a series of well-established organic reactions, including amide coupling and Boc protection. These methods ensure high purity and yield, meeting the stringent requirements of pharmaceutical-grade materials. Researchers often optimize these protocols to achieve scalability, a critical factor for industrial applications.

Another area of interest is the compound's potential in cancer research. Preliminary studies suggest that derivatives of CAS 1060813-90-2 may exhibit anti-proliferative activity against certain cancer cell lines. This has sparked a wave of investigations into its mechanism of action and structure-activity relationships, with the aim of developing novel therapeutic agents.

From a commercial perspective, 3-{4-(tert-butoxy)carbonyl-3-methylpiperazin-1-yl}propanoic acid is available from several reputable suppliers, often with detailed certificates of analysis (CoA) to ensure quality and consistency. Pricing and availability can vary depending on the quantity and purity required, but the compound is generally accessible to academic and industrial researchers alike.

In conclusion, 3-{4-(tert-butoxy)carbonyl-3-methylpiperazin-1-yl}propanoic acid (CAS 1060813-90-2) is a versatile and valuable compound in the field of chemical and pharmaceutical research. Its unique properties and wide-ranging applications make it a subject of ongoing study and innovation. As research continues to uncover new uses for this molecule, its importance in drug discovery and development is likely to grow even further.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)