• 1. An automatic determination of thoria in thoria-urania mixtures
  Analyst, 1966,91, 208-210
• 2. An alumina stabilized graphene oxide wrapped SnO2 hollow sphere LIB anode with improved lithium storage?
  Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789
• 3. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?
  Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
• 4. An insight into the hybridization mechanism of hairpin DNA physically immobilized on chemically modified graphenes
  Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
• 5. Alumina coating on 5 V lithium cobalt fluorophosphate cathode material for lithium secondary batteries – synthesis and electrochemical properties?
  S. Amaresh,K. Karthikeyan,K. J. Kim,Y. S. Lee RSC Adv., 2014,4, 23107-23115

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxylic acids

4-Hydroxy-2-methylnicotinic acid (CAS No. 1060806-08-7): A Comprehensive Overview of Its Properties and Applications

4-Hydroxy-2-methylnicotinic acid (CAS No. 1060806-08-7) is a specialized organic compound that has garnered significant attention in the fields of pharmaceutical research, agrochemical development, and material science. This compound, also known as 2-methyl-4-hydroxynicotinic acid, belongs to the class of hydroxypyridine derivatives, which are widely recognized for their versatile chemical properties and biological activities. The increasing interest in this molecule is driven by its potential applications in drug synthesis, enzyme inhibition studies, and as a building block for heterocyclic compounds.

One of the most frequently searched questions about 4-Hydroxy-2-methylnicotinic acid is its role in medicinal chemistry. Researchers are particularly interested in its ability to serve as a precursor for the synthesis of bioactive molecules, including potential anti-inflammatory agents and antioxidants. Recent studies have explored its interactions with biological targets, such as enzymes involved in metabolic pathways, making it a subject of interest for drug discovery projects. Additionally, its structural similarity to nicotinic acid (vitamin B3) has sparked investigations into its potential nutraceutical applications.

From a chemical perspective, 4-Hydroxy-2-methylnicotinic acid exhibits unique properties due to the presence of both a hydroxyl group and a carboxylic acid moiety on its pyridine ring. This combination allows for diverse chemical modifications, such as esterification, amidation, and halogenation, which are critical for tailoring its reactivity in synthetic applications. The compound’s solubility profile (soluble in polar solvents like water and ethanol) and thermal stability further enhance its utility in industrial processes.

In the context of green chemistry, 4-Hydroxy-2-methylnicotinic acid has been explored as a sustainable intermediate for eco-friendly synthesis routes. With growing emphasis on environmentally benign processes, researchers are investigating its use in catalysis and biodegradable material production. This aligns with current trends in circular economy initiatives, where the demand for renewable chemical feedstocks is rising.

Another hot topic related to this compound is its potential in agricultural chemistry. Studies suggest that derivatives of 4-Hydroxy-2-methylnicotinic acid may act as plant growth regulators or pesticide synergists. Its mode of action in crop protection formulations is under investigation, particularly in the development of low-toxicity agrochemicals. This resonates with the global push toward sustainable farming practices and reduced environmental impact.

Analytical techniques such as HPLC, NMR spectroscopy, and mass spectrometry are commonly employed to characterize 4-Hydroxy-2-methylnicotinic acid and ensure its purity for research applications. Quality control is paramount, especially when the compound is used in pharmaceutical intermediates or high-purity reagents. Suppliers often highlight its ≥98% purity grade to meet the stringent requirements of GMP-compliant laboratories.

In summary, 4-Hydroxy-2-methylnicotinic acid (CAS No. 1060806-08-7) is a multifaceted compound with expanding relevance across scientific disciplines. Its applications span from drug development to green chemistry, addressing contemporary challenges in health and sustainability. As research progresses, this molecule is poised to play an even greater role in innovative chemical solutions.

• 82-82-6(4-Pyridoxic Acid)
• 7442-76-4(4-Pyridinecarboxylic acid, 5-formyl-3-hydroxy-2-methyl-)
• 61547-30-6(3-Pyridinecarboxylic acid, 4-formyl-5-hydroxy-6-methyl-)
• 479-30-1(5-Hydroxy-6-methyl-3,4-pyridinedicarboxylic Acid)
• 90564-35-5(3,4-Pyridinedicarboxylicacid, 5-hydroxy-2,6-dimethyl-)
• 89942-78-9( )
• 103853-86-7(3-Quinolinecarboxylicacid, 7-hydroxy-2-methyl-)
• 58322-80-8(4-Pyridinecarboxylic acid, 3-hydroxy-5-(hydroxymethyl)-2-methyl-, sodium salt (1:1))
• 524-07-2(5-pyridoxic acid)
• 89937-79-1(5-hydroxy-2-methylpyridine-3-carboxylic acid)