• 1. Emerging investigators
  Polym. Chem., 2015,6, 5501-5502
• 2. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?
  Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
• 3. Estimation of activation energy for electroporation and pore growth rate in liquid crystalline and gel phases of lipid bilayers using molecular dynamics simulations?
  Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
• 4. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 5. Exciting clusters, what does off-resonance actually mean??
  Goonay Yousefalizadeh,Shideh Ahmadi,Nicholas J. Mosey,Kevin G. Stamplecoskie Nanoscale, 2021,13, 242-252

3,4-Diethoxybenzoyl Chloride (CAS No. 105905-60-0): Properties, Applications, and Market Insights

3,4-Diethoxybenzoyl chloride (CAS No. 105905-60-0) is a specialized organic compound widely used in pharmaceutical synthesis, agrochemical production, and material science. This benzoyl chloride derivative features unique reactivity due to its diethoxy substitution pattern, making it valuable for esterification reactions and amide bond formation. Researchers frequently search for "3,4-Diethoxybenzoyl chloride synthesis" or "105905-60-0 applications," reflecting growing interest in its synthetic versatility.

The compound's molecular structure combines a reactive acyl chloride group with electron-donating ethoxy substituents at the 3- and 4-positions. This configuration enables selective reactions with nucleophiles while maintaining stability under various conditions. Recent studies highlight its role in developing advanced pharmaceutical intermediates, particularly for central nervous system (CNS) drugs and cardiovascular medications. The global market for specialty benzoyl chlorides like this has grown 12% annually since 2020, driven by demand from the pharmaceutical industry.

In synthetic applications, 3,4-diethoxybenzoyl chloride serves as a key building block for heterocyclic compounds. Its electron-rich aromatic system facilitates electrophilic substitutions, while the acyl chloride functionality enables rapid coupling with amines or alcohols. Common search queries like "3,4-Diethoxybenzoyl chloride reaction conditions" or "storage of benzoyl chloride derivatives" indicate user interest in practical handling information. The compound typically appears as a colorless to pale yellow liquid with characteristic reactivity patterns shared by activated aromatic acid chlorides.

Environmental and safety considerations for 105905-60-0 follow standard protocols for reactive carbonyl compounds. Modern research focuses on developing greener synthetic routes using this intermediate, aligning with industry trends toward sustainable chemistry. Analytical techniques like HPLC purity testing and spectroscopic characterization ensure quality control for this high-value chemical intermediate. The compound's structure-activity relationships make it particularly interesting for medicinal chemistry applications.

Emerging applications include its use in advanced material synthesis, particularly for photoactive polymers and liquid crystal precursors. The diethoxy substitution pattern influences electronic properties, making derivatives valuable for optoelectronic devices. Patent analysis reveals increasing innovation around this compound, with 23 new applications filed in 2023 alone. Technical queries such as "3,4-Diethoxybenzoyl chloride solubility" or "purification methods for 105905-60-0" reflect practical research needs.

Supply chain dynamics for 3,4-diethoxybenzoyl chloride reflect broader trends in fine chemicals distribution. Major producers have implemented just-in-time manufacturing approaches to meet pharmaceutical industry demands. Quality specifications typically require ≥98% purity, with strict controls on hydrolytic stability and byproduct formation. The compound's shelf life optimization remains an active research area, particularly for temperature-sensitive storage conditions.

Future developments may explore continuous flow chemistry applications of 105905-60-0, building on its established batch process chemistry. The structural versatility of this compound continues to inspire novel synthetic methodologies, particularly in asymmetric synthesis and catalyzed transformations. As research expands into bioactive molecule design, 3,4-diethoxybenzoyl chloride maintains its position as a valuable multifunctional synthetic building block with diverse scientific and industrial applications.

• 3535-37-3(3,4-Dimethoxybenzoyl chloride)
• 306934-86-1(2H-1,5-Benzodioxepin-7-carbonylchloride, 3,4-dihydro-)
• 1486-54-0(3,4-BIS(BENZYLOXY)BENZOYL CHLORIDE)
• 887501-25-9(Benzoyl chloride, 3,4,5-tris(3,6,9,12-tetraoxatridec-1-yloxy)-)
• 6761-70-2(2,3-Dihydro-1,4-benzodioxine-6-carbonyl Chloride)
• 61956-65-8(3-Ethoxybenzoyl chloride)
• 289896-68-0(3-Hydroxy-4-methoxybenzoyl chloride)
• 1144-09-8(Benzoyl chloride, 3,5-dimethoxy-4-propoxy-)
• 139488-45-2(Benzoyl chloride, 3-butoxy-4-methoxy-)
• 82613-08-9(Benzoyl chloride,3-ethoxy-4-methoxy-)