• 1. Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored “hydrophobic channel”
  Zhongxia Zhou,Tao Liu,Dongwei Kang,Zhipeng Huo,Gaochan Wu,Dirk Daelemans,Erik De Clercq,Christophe Pannecouque,Peng Zhan,Xinyong Liu Org. Biomol. Chem. 2018 16 1014
• 2. Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored “hydrophobic channel”
  Zhongxia Zhou,Tao Liu,Dongwei Kang,Zhipeng Huo,Gaochan Wu,Dirk Daelemans,Erik De Clercq,Christophe Pannecouque,Peng Zhan,Xinyong Liu Org. Biomol. Chem. 2018 16 1014
• 3. Targeting the hydrophobic channel of NNIBP: discovery of novel 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs with high potency against wild-type and K103N mutant virus
  Zhongxia Zhou,Tao Liu,Gaochan Wu,Dongwei Kang,Zhipeng Fu,Zhao Wang,Erik De Clercq,Christophe Pannecouque,Peng Zhan,Xinyong Liu Org. Biomol. Chem. 2019 17 3202
• 4. A review on iodine speciation for environmental, biological and nutrition fields
  Antonio Moreda-Pi?eiro,Vanessa Romarís-Hortas,Pilar Bermejo-Barrera J. Anal. At. Spectrom. 2011 26 2107
• 5. Atomic Spectrometry Update–Environmental analysis
  JOHN R. DEAN,OWEN BUTLER,ANDREW FISHER,LOUIS M. GARDEN,MALCOLM S. CRESSER,PETER WATKINS,MARK CAVE J. Anal. At. Spectrom. 1998 13 1R

• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Comprehensive Overview of 4-Iodo-2,6-dimethylphenol (CAS No. 10570-67-9): Properties, Applications, and Industry Insights

4-Iodo-2,6-dimethylphenol (CAS No. 10570-67-9) is a halogenated aromatic compound with significant relevance in organic synthesis and specialty chemical applications. Its molecular structure, featuring an iodine substituent at the para position and methyl groups at the ortho positions, makes it a versatile intermediate for pharmaceuticals, agrochemicals, and advanced material research. The compound’s unique reactivity, particularly in cross-coupling reactions like Suzuki or Ullmann couplings, aligns with growing interest in sustainable chemistry and catalysis—topics frequently searched in academic and industrial forums.

Recent studies highlight the role of 4-Iodo-2,6-dimethylphenol in developing antimicrobial agents, a hotspot due to rising global concerns over antibiotic resistance. Researchers leverage its iodo-functional group to create derivatives with enhanced bioactivity, addressing queries like “halogenated phenol applications in medicine” often seen in PubMed and Google Scholar trends. Additionally, its stability under moderate conditions makes it a candidate for high-performance polymer modifiers, resonating with searches on “phenolic compounds in material science.”

From a synthetic perspective, the compound’s crystalline form and solubility profile (soluble in ethanol, acetone) are frequently discussed in patents and process optimization guides. Industry professionals searching for “iodophenol synthesis scalability” will find its gram-to-kilogram production protocols well-documented. Environmental considerations are also addressed, as its low volatility aligns with green chemistry principles—a trending topic in regulatory compliance discussions.

Analytical methods for 4-Iodo-2,6-dimethylphenol, such as HPLC and GC-MS, are critical for quality control, reflecting common search terms like “halogenated phenol analysis techniques.” Its NMR spectra (characteristic peaks at 2.3 ppm for methyl groups and 7.1 ppm for aromatic protons) serve as a reference in spectral databases, catering to queries from synthetic chemists.

In conclusion, 4-Iodo-2,6-dimethylphenol (CAS No. 10570-67-9) bridges multiple disciplines, from drug discovery to material engineering. Its alignment with industry trends—such as precision synthesis and bioactive scaffolds—ensures sustained relevance in both academic and commercial spheres, answering the demand for specialized, well-characterized chemical building blocks.

• 60577-30-2(4-Iodo-2-methylphenol)
• 183803-06-7(5-Iodo-2-methylphenol)
• 90003-93-3(Phenol,2-iodo-4,6-dimethyl-)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)