Cas no 1056139-87-7 (4-(trifluoromethyl)-1H-pyrazol-3-amine)
4-(Trifluoromethyl)-1H-pyrazol-3-amine is a versatile heterocyclic compound featuring a trifluoromethyl group and an amine functionality on a pyrazole scaffold. Its unique structure makes it a valuable intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of active ingredients with enhanced bioactivity and metabolic stability. The trifluoromethyl group contributes to increased lipophilicity and electron-withdrawing properties, while the amine moiety allows for further functionalization. This compound is particularly useful in medicinal chemistry for designing kinase inhibitors, antimicrobial agents, and other bioactive molecules. Its stability and reactivity under controlled conditions make it a reliable building block for research and industrial applications.
1056139-87-7 structure
Product Name:4-(trifluoromethyl)-1H-pyrazol-3-amine
CAS No:1056139-87-7
MF:C4H4F3N3
MW:151.089870452881
MDL:MFCD13190431
CID:69767
PubChem ID:23569312
Update Time:2025-06-07
4-(trifluoromethyl)-1H-pyrazol-3-amine Chemical and Physical Properties
Names and Identifiers
-
- 4-Trifluoromethyl-1H-pyrazol-3-amine
- 4-(trifluoromethyl)-1H-Pyrazol-3-amine
- 4-(trifluoromethyl)-1H-pyrazol-5-amine
- 4-Trifluoromethyl-1H-pyrazol-3-ylamine
- 1H-Pyrazol-3-aMine, 4-(trifluoroMethyl)-
- SB12495
- BB 0261912
- KS-8908
- AKOS016344495
- SCHEMBL20542069
- KBVOILKOLGWPBG-UHFFFAOYSA-N
- P11651
- BB 0261913
- SY117455
- 1056139-87-7
- 3-amino-4-trifluoromethylpyrazole
- 3-Amino-4-(trifluoromethyl)pyrazole
- 4-(Trifluoromethyl)-1H-pyrazol-3-amine HCl
- FT-0749455
- AMY39145
- CS-0054091
- A857859
- SCHEMBL11192096
- DTXSID90635007
- MFCD13190431
- C4H4F3N3
- DB-059372
- 4-(trifluoromethyl)-1H-pyrazol-3-amine
-
- MDL： MFCD13190431
- Inchi： 1S/C4H4F3N3/c5-4(6,7)2-1-9-10-3(2)8/h1H,(H3,8,9,10)
- InChI Key： KBVOILKOLGWPBG-UHFFFAOYSA-N
- SMILES： FC(C1C=NNC=1N)(F)F
Computed Properties
- Exact Mass: 151.03600
- Monoisotopic Mass: 151.036
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 123
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 54.7A^2
- XLogP3: 0.8
Experimental Properties
- Density: 1.561
- Boiling Point: 284 oC
- Flash Point: 125 oC
- PSA: 54.70000
- LogP: 1.59190
4-(trifluoromethyl)-1H-pyrazol-3-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM188491-100mg |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 95+% | 100mg |
$342 | 2021-08-05 | |
| Chemenu | CM188491-250mg |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 95+% | 250mg |
$658 | 2021-08-05 | |
| Chemenu | CM188491-1g |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 95+% | 1g |
$1316 | 2021-08-05 | |
| abcr | AB402531-250 mg |
4-Trifluoromethyl-1H-pyrazol-3-amine; . |
1056139-87-7 | 250MG |
€268.80 | 2022-06-10 | ||
| abcr | AB402531-1 g |
4-Trifluoromethyl-1H-pyrazol-3-amine; . |
1056139-87-7 | 1g |
€622.10 | 2022-06-10 | ||
| Chemenu | CM188491-250mg |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 95%+ | 250mg |
$405 | 2023-02-03 | |
| Chemenu | CM188491-1g |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 95%+ | 1g |
$810 | 2023-02-03 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 68R0473-1g |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 96% | 1g |
8463.46CNY | 2021-05-08 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 68R0473-5g |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 96% | 5g |
33904.74CNY | 2021-05-08 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 68R0473-500mg |
4-Trifluoromethyl-1H-pyrazol-3-ylamine |
1056139-87-7 | 96% | 500mg |
4655.75CNY | 2021-05-08 |
4-(trifluoromethyl)-1H-pyrazol-3-amine Related Literature
-
Stephen P. Fletcher,Richard B. C. Jagt,Ben L. Feringa Chem. Commun., 2007, 2578-2580
-
Suji Lee,Min Su Han Chem. Commun., 2021,57, 9450-9453
-
P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
-
Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
-
Siquan Zhang,Shengyao Wang,Liping Guo,Hao Chen,Bien Tan,Shangbin Jin J. Mater. Chem. C, 2020,8, 192-200
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