Cas no 105391-43-3 (6-(Trifluoromethoxy)-1H-indazole)
6-(Trifluoromethoxy)-1H-indazole is a heterocyclic organic compound featuring an indazole core substituted with a trifluoromethoxy group at the 6-position. This structure imparts unique physicochemical properties, including enhanced lipophilicity and metabolic stability, making it a valuable intermediate in pharmaceutical and agrochemical research. The trifluoromethoxy group contributes to improved bioavailability and resistance to enzymatic degradation, while the indazole scaffold offers versatile reactivity for further functionalization. Its applications include the development of bioactive molecules, particularly in kinase inhibition and CNS-targeted therapeutics. The compound is characterized by high purity and consistent performance, ensuring reliability in synthetic and medicinal chemistry applications.
105391-43-3 structure
Product Name:6-(Trifluoromethoxy)-1H-indazole
CAS No:105391-43-3
MF:C8H5F3N2O
MW:202.133311986923
MDL:MFCD27993300
CID:2623837
PubChem ID:13712997
Update Time:2025-06-07
6-(Trifluoromethoxy)-1H-indazole Chemical and Physical Properties
Names and Identifiers
-
- 6-(TRIFLUOROMETHOXY)-1H-INDAZOLE
- SCHEMBL10601519
- MFCD27993300
- CS-0107227
- D76711
- DTXSID60547421
- 105391-43-3
- 1H-Indazole, 6-(trifluoromethoxy)-
- 6-trifluoromethoxyindazole
- 823-003-6
- DTXCID40498205
- 6-(Trifluoromethoxy)-1H-indazole
-
- MDL： MFCD27993300
- Inchi： 1S/C8H5F3N2O/c9-8(10,11)14-6-2-1-5-4-12-13-7(5)3-6/h1-4H,(H,12,13)
- InChI Key： YXUMGPCNHDVHBV-UHFFFAOYSA-N
- SMILES： FC(OC1C=CC2C=NNC=2C=1)(F)F
Computed Properties
- Exact Mass: 202.03539727g/mol
- Monoisotopic Mass: 202.03539727g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 14
- Rotatable Bond Count: 1
- Complexity: 209
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.4
- Topological Polar Surface Area: 37.9?2
6-(Trifluoromethoxy)-1H-indazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Apollo Scientific | PC56142-250mg |
6-(Trifluoromethoxy)-1H-indazole |
105391-43-3 | 95% | 250mg |
￡147.00 | 2025-02-21 | |
| Apollo Scientific | PC56142-1g |
6-(Trifluoromethoxy)-1H-indazole |
105391-43-3 | 95% | 1g |
￡450.00 | 2025-02-21 | |
| Chemenu | CM420351-1g |
1H-Indazole, 6-(trifluoromethoxy)- |
105391-43-3 | 95%+ | 1g |
$675 | 2023-02-19 | |
| eNovation Chemicals LLC | D770153-100mg |
1H-Indazole, 6-(trifluoromethoxy)- |
105391-43-3 | 95% | 100mg |
$170 | 2024-06-07 | |
| eNovation Chemicals LLC | D770153-250mg |
1H-Indazole, 6-(trifluoromethoxy)- |
105391-43-3 | 95% | 250mg |
$195 | 2024-06-07 | |
| eNovation Chemicals LLC | Y1298187-1G |
6-(trifluoromethoxy)-1H-indazole |
105391-43-3 | 97% | 1g |
$195 | 2024-07-21 | |
| eNovation Chemicals LLC | Y1298187-5G |
6-(trifluoromethoxy)-1H-indazole |
105391-43-3 | 97% | 5g |
$575 | 2024-07-21 | |
| eNovation Chemicals LLC | Y1298187-10G |
6-(trifluoromethoxy)-1H-indazole |
105391-43-3 | 97% | 10g |
$980 | 2024-07-21 | |
| eNovation Chemicals LLC | Y1298187-25G |
6-(trifluoromethoxy)-1H-indazole |
105391-43-3 | 97% | 25g |
$2085 | 2024-07-21 | |
| Aaron | AR007XC6-100mg |
1H-Indazole, 6-(trifluoromethoxy)- |
105391-43-3 | 98% | 100mg |
$63.00 | 2025-02-10 |
6-(Trifluoromethoxy)-1H-indazole Related Literature
-
Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
-
Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
-
Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
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4. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
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