Cas no 105316-06-1 (4-(Morpholin-4-yl)-3-(trifluoromethyl)aniline)

4-(Morpholin-4-yl)-3-(trifluoromethyl)aniline is a versatile aromatic amine derivative featuring both a morpholine ring and a trifluoromethyl group. The morpholine moiety enhances solubility and reactivity, while the electron-withdrawing trifluoromethyl group influences the compound's electronic properties, making it valuable in pharmaceutical and agrochemical synthesis. Its structural features enable applications as an intermediate in the development of biologically active molecules, particularly in the design of kinase inhibitors and other therapeutic agents. The compound's stability and functional group compatibility further support its utility in cross-coupling reactions and other synthetic transformations. Proper handling under inert conditions is recommended due to its amine functionality.
4-(Morpholin-4-yl)-3-(trifluoromethyl)aniline structure
105316-06-1 structure
Product Name:4-(Morpholin-4-yl)-3-(trifluoromethyl)aniline
CAS No:105316-06-1
MF:C11H13F3N2O
MW:246.228933095932
MDL:MFCD06090415
CID:1026146
PubChem ID:2771329
Update Time:2025-10-29

4-(Morpholin-4-yl)-3-(trifluoromethyl)aniline Chemical and Physical Properties

Names and Identifiers

    • 4-Morpholino-3-(trifluoromethyl)aniline
    • 4-Morpholin-4-yl-3-trifluoromethyl-phenylamine
    • 4-Morpholino-3-(trifluoromethyl)benzenamine
    • 005820
    • 3-trifluoromethyl-4-morpholinoaniline
    • 4-(morpholin-4-yl)-3-(trifluoromethyl)aniline
    • 4-morpholin-4-yl-3-(trifluoro-methyl)anilin
    • 4-morpholin-4-yl-3-trifluoromethyl-aniline
    • 5-amino-2-(4-morpholinyl)benzotrifluoride
    • AC1MCJSJ
    • ACMC-20a5nv
    • ST093230
    • ZERO
    • DTXSID40377925
    • F87758
    • Benzenamine, 4-(4-morpholinyl)-3-(trifluoromethyl)-
    • MFCD06090415
    • SCHEMBL1929073
    • 4-(4-Morpholinyl-3-trifluoromethylaniline
    • 105316-06-1
    • AKOS000101817
    • [4-morpholin-4-yl-3-(trifluoromethyl)phenyl]amine
    • 4-morpholin-4-yl-3-(trifluoromethyl)aniline
    • XYYCEENJHNNMIR-UHFFFAOYSA-N
    • [4-(4-morpholinyl)-3-(trifluoromethyl)phenyl]amine
    • 4-Morpholin-4-yl-3-trifluoromethyl-phenylamine, AldrichCPR
    • STK519629
    • DB-332451
    • ALBB-026193
    • 4-(Morpholin-4-yl)-3-(trifluoromethyl)aniline
    • MDL： MFCD06090415
    • Inchi： 1S/C11H13F3N2O/c12-11(13,14)9-7-8(15)1-2-10(9)16-3-5-17-6-4-16/h1-2,7H,3-6,15H2
    • InChI Key： WRKWRSUBQVBAQB-UHFFFAOYSA-N
    • SMILES： FC(C1C=C(C=CC=1N1CCOCC1)N)(F)F

Computed Properties

  • Exact Mass: 246.09809
  • Monoisotopic Mass: 246.098
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 2
  • Complexity: 254
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 38.5A^2
  • XLogP3: 1.9

Experimental Properties

  • PSA: 38.49
  • LogP: 2.77040

4-(Morpholin-4-yl)-3-(trifluoromethyl)aniline Pricemore >>

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