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  Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
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  Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

2-Hydroxycyclopent-2-en-1-one (CAS No. 10493-98-8): A Versatile Cyclic Enone in Modern Chemistry

2-Hydroxycyclopent-2-en-1-one (CAS 10493-98-8), a cyclic α,β-unsaturated ketone with a hydroxyl group, is a pivotal intermediate in organic synthesis. Its unique cyclopentenone scaffold combines reactivity from both the enone system and the hydroxyl functionality, making it valuable for constructing complex molecules. Researchers frequently search for "synthesis of 2-hydroxycyclopentenone" or "applications of CAS 10493-98-8," reflecting its relevance in pharmaceuticals, fragrances, and agrochemicals.

The compound’s Michael acceptor properties enable conjugate addition reactions, a hotspot in green chemistry. With growing interest in sustainable methods, queries like "biocatalytic transformations of cyclopentenones" highlight its role in enzymatic synthesis. The hydroxyl group further allows O-functionalization, addressing demands for "selective derivatization of hydroxyenones" in drug discovery.

In material science, 10493-98-8 serves as a precursor for conducting polymers and coordination complexes. Recent studies explore its use in metal-organic frameworks (MOFs), aligning with trends in "MOF design for carbon capture." Its UV absorption characteristics also attract attention for "photoresponsive materials," a trending topic in nanotechnology forums.

Analytical challenges, such as "HPLC quantification of cyclopentenone derivatives," underscore the need for robust protocols. Advanced techniques like LC-MS and NMR are often discussed in relation to 2-Hydroxycyclopent-2-en-1-one purity assessment, crucial for industries prioritizing "high-purity intermediates."

Environmental considerations drive searches for "biodegradation of cyclic ketones." While 10493-98-8 is not classified as hazardous, its eco-friendly disposal methods are frequently queried, reflecting the shift toward green chemistry principles.

In summary, 2-Hydroxycyclopent-2-en-1-one bridges fundamental research and industrial applications. Its adaptability to catalytic asymmetric synthesis and click chemistry positions it as a staple in modern labs, answering the demand for "multifunctional building blocks" across scientific disciplines.

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