• 1. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 2. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 3. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 4. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
• 5. Evolution study of photo-synthesized gold nanoparticles by spectral deconvolution model: a quantitative approach
  Chung-Sung Yang,Mong-Shian Shih,Fang-Yi Chang New J. Chem., 2006,30, 729-735

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenethylamines

Introduction to N-Phenethylpropan-1-amine Hydrochloride (CAS No. 104178-96-3)

N-Phenethylpropan-1-amine hydrochloride, a compound with the chemical formula C₁₁H₁₇NCl, is a derivative of the amine class that has garnered significant attention in the field of pharmaceutical research and development. This compound, identified by its unique CAS number 104178-96-3, is particularly studied for its potential biological activities and its role in the synthesis of various pharmacologically relevant molecules. The hydrochloride salt form enhances its solubility and stability, making it a valuable intermediate in synthetic chemistry and a candidate for further exploration in drug discovery.

The chemical structure of N-Phenethylpropan-1-amine hydrochloride consists of a propyl chain substituted with an amine group, which is further modified by the presence of a phenethyl moiety. This structural motif is reminiscent of several known bioactive compounds, suggesting that it may exhibit similar pharmacological properties. The presence of the hydrochloride salt indicates that the compound is protonated at the amine group, which can influence its interactions with biological targets and its overall pharmacokinetic profile.

In recent years, there has been a growing interest in exploring novel amine derivatives as potential therapeutic agents. N-Phenethylpropan-1-amine hydrochloride has been investigated for its possible role in modulating neurotransmitter systems, particularly those involving dopamine and serotonin. These neurotransmitters are implicated in a wide range of physiological processes, including mood regulation, pain perception, and motor control. Therefore, compounds that can interact with these systems hold promise for the development of new treatments for neurological and psychiatric disorders.

One of the most compelling aspects of N-Phenethylpropan-1-amine hydrochloride is its potential as a scaffold for drug design. The phenethylamine core is a well-known structural motif found in several psychoactive substances, but it also serves as a basis for developing drugs with therapeutic benefits. By modifying various functional groups attached to this core structure, researchers can fine-tune the pharmacological properties of the compound. For instance, introducing additional substituents can alter its affinity for specific receptors or enzymes, thereby enhancing its efficacy or reducing side effects.

Recent studies have demonstrated that N-Phenethylpropan-1-amine hydrochloride exhibits inhibitory activity against certain enzymes involved in inflammation and pain pathways. This has led to investigations into its potential use as an anti-inflammatory or analgesic agent. The compound's ability to interact with inflammatory mediators and modulate pain signaling pathways makes it an attractive candidate for further clinical development. Preclinical studies have shown promising results in animal models, suggesting that it may have therapeutic value in conditions such as arthritis or neuropathic pain.

The synthesis of N-Phenethylpropan-1-amine hydrochloride involves multi-step organic reactions that require careful optimization to ensure high yield and purity. Common synthetic routes include nucleophilic substitution reactions followed by salt formation to obtain the hydrochloride salt. Advanced techniques such as catalytic hydrogenation and protecting group strategies are often employed to achieve the desired product with minimal byproducts. The development of efficient synthetic methodologies is crucial for scaling up production and making this compound more accessible for research purposes.

In addition to its pharmacological potential, N-Phenethylpropan-1-amine hydrochloride has also been explored as a tool compound in biochemical research. Its well-defined structure and known biological activity make it useful for studying receptor binding mechanisms and signal transduction pathways. Researchers can use this compound to investigate how it interacts with target proteins and how these interactions lead to changes in cellular function. Such studies can provide valuable insights into disease mechanisms and help identify new therapeutic targets.

The future prospects of N-Phenethylpropan-1-amine hydrochloride are promising, with ongoing research aimed at elucidating its full pharmacological profile and exploring new applications. As our understanding of biological systems continues to expand, compounds like this one will play an increasingly important role in drug discovery and development. Collaborative efforts between chemists, biologists, and clinicians will be essential to translate laboratory findings into effective treatments for human diseases.

In conclusion, N-Phenethylpropan-1-amine hydrochloride (CAS No. 104178-96-3) is a versatile compound with significant potential in pharmaceutical research. Its unique chemical structure and biological activities make it an attractive candidate for further exploration as a therapeutic agent or as a tool compound in biochemical studies. With continued research and development, this compound is poised to contribute to advancements in medicine and our understanding of complex biological processes.

• 137069-23-9(methyl[2-(3-methylphenyl)ethyl]amine)
• 589-08-2(N-Methyl-2-phenylethylamine)
• 229621-74-3(Methyl-(2-p-tolyl-ethyl)-amine)
• 13977-33-8(Demelverine)
• 27906-91-8((2-phenylethyl)(propyl)amine)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)