Cas no 10408-89-6 (N-Methyl-1-phenylethanamine hydrochloride)

N-Methyl-1-phenylethanamine hydrochloride is a chiral amine salt with applications in organic synthesis and pharmaceutical research. Its hydrochloride form enhances stability and solubility, making it suitable for precise experimental use. The compound serves as a key intermediate in the preparation of bioactive molecules, particularly those requiring a phenethylamine scaffold. Its defined stereochemistry allows for controlled enantioselective reactions, which is valuable in asymmetric synthesis. The crystalline solid form ensures consistent purity and handling. Due to its structural features, it is often utilized in the development of pharmacologically active compounds, including potential CNS-targeting agents. Proper storage under anhydrous conditions is recommended to maintain integrity.
N-Methyl-1-phenylethanamine hydrochloride structure
10408-89-6 structure
Product Name:N-Methyl-1-phenylethanamine hydrochloride
CAS No:10408-89-6
MF:C9H14ClN
MW:171.667161464691
MDL:MFCD09866174
CID:840901
PubChem ID:24213016
Update Time:2025-10-20

N-Methyl-1-phenylethanamine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • N-Methyl-1-phenylethanamine hydrochloride
    • Benzenemethanamine, N,.alpha.-dimethyl-, hydrochloride (1:1)
    • Methyl(1-phenylethyl)aMine, HCl
    • N,α-Dimethylbenzenemethanamine hydrochloride
    • Benzylamine, N,alpha-dimethyl-, hydrochloride
    • SB45273
    • methyl(1-phenylethyl)amine hydrochloride
    • Benzenemethanamine, N,alpha-dimethyl-, hydrochloride (1:1)
    • MFCD28138033
    • BENZYLAMINE, N,.ALPHA.-DIMETHYL-, HYDROCHLORIDE
    • CS-0205686
    • N-Methyl-1-phenylethylamine hydrochloride
    • UNII-IR684460XY
    • Methyl (1-phenylethyl)amine hydrochloride
    • MFCD09866174
    • SY316893
    • Q27280860
    • N-Methyl-1-phenylethan-1-amine--hydrogen chloride (1/1)
    • Methyl(1-Phenylethyl)amine HCl
    • DB-032311
    • BENZENEMETHANAMINE, N,.ALPHA.-DIMETHYL-, HCL (1:1)
    • IR684460XY
    • N-methyl-1-phenylethanamine;hydrochloride
    • N-Methyl-1-phenylethanaminehydrochloride
    • L10186
    • AKOS015891446
    • AS-19480
    • 10408-89-6
    • EN300-30239
    • DTXSID30639968
    • MDL： MFCD09866174
    • Inchi： 1S/C9H13N.ClH/c1-8(10-2)9-6-4-3-5-7-9;/h3-8,10H,1-2H3;1H
    • InChI Key： CLMUXERMQYHMJN-UHFFFAOYSA-N
    • SMILES： Cl.N(C)C(C)C1C=CC=CC=1

Computed Properties

  • Exact Mass: 171.0814771g/mol
  • Monoisotopic Mass: 171.0814771g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 84.7
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 12?2

Experimental Properties

  • Melting Point: 72-173 oC

N-Methyl-1-phenylethanamine hydrochloride Security Information

N-Methyl-1-phenylethanamine hydrochloride Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A019064122-250mg
N-Methyl-1-phenylethan-1-amine hydrochloride
 10408-89-6 97%
250mg
 $680.00 2023-09-04
Alichem
A019064122-500mg
N-Methyl-1-phenylethan-1-amine hydrochloride
 10408-89-6 97%
500mg
 $980.00 2023-09-04
Alichem
A019064122-1g
N-Methyl-1-phenylethan-1-amine hydrochloride
 10408-89-6 97%
1g
 $1685.00 2023-09-04
TRC
M339503-25mg
N-Methyl-1-phenylethanamine hydrochloride
 10408-89-6
25mg
 $ 50.00 2022-06-02
TRC
M339503-50mg
N-Methyl-1-phenylethanamine hydrochloride
 10408-89-6
50mg
 $ 65.00 2022-06-02
TRC
M339503-250mg
N-Methyl-1-phenylethanamine hydrochloride
 10408-89-6
250mg
 $ 80.00 2022-06-02
Enamine
EN300-30239-1g
methyl(1-phenylethyl)amine hydrochloride
 10408-89-6 95%
1g
 $25.0 2023-09-06
Enamine
EN300-30239-5g
methyl(1-phenylethyl)amine hydrochloride
 10408-89-6 95%
5g
 $47.0 2023-09-06
Enamine
EN300-30239-10g
methyl(1-phenylethyl)amine hydrochloride
 10408-89-6 95%
10g
 $77.0 2023-09-06
Enamine
EN300-30239-0.05g
methyl(1-phenylethyl)amine hydrochloride
 10408-89-6 95%
0.05g
 $19.0 2023-09-06

N-Methyl-1-phenylethanamine hydrochloride Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:10408-89-6)N-Methyl-1-phenylethanamine hydrochloride
Order Number:A896291
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 11:54
Price ($):233.0

N-Methyl-1-phenylethanamine hydrochloride Related Literature

Related Categories

Additional information on N-Methyl-1-phenylethanamine hydrochloride

Research Briefing on N-Methyl-1-phenylethanamine Hydrochloride (CAS: 10408-89-6): Recent Advances and Applications

N-Methyl-1-phenylethanamine hydrochloride (CAS: 10408-89-6) is a chemical compound of significant interest in the pharmaceutical and chemical biology fields. This briefing synthesizes the latest research findings, focusing on its synthesis, pharmacological properties, and potential applications. Recent studies have highlighted its role as a key intermediate in the synthesis of novel psychoactive substances (NPS) and its implications in central nervous system (CNS) modulation. The compound's structural similarity to amphetamine derivatives has spurred investigations into its metabolic pathways and receptor interactions, particularly with dopamine and serotonin transporters.

A 2023 study published in the Journal of Medicinal Chemistry explored the enantioselective synthesis of N-Methyl-1-phenylethanamine hydrochloride, demonstrating improved yield and purity through catalytic asymmetric methods. The research emphasized the compound's utility in producing optically active intermediates for antidepressants and stimulants. Additionally, advancements in green chemistry have enabled more sustainable production processes, reducing environmental impact while maintaining high efficacy.

Pharmacological evaluations have revealed that N-Methyl-1-phenylethanamine hydrochloride exhibits moderate affinity for the dopamine D2 receptor, suggesting potential applications in treating neuropsychiatric disorders. However, its abuse potential and regulatory status remain under scrutiny, with the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) flagging it as a substance of concern. Recent in vitro and in vivo studies have also investigated its metabolic stability, identifying cytochrome P450 enzymes as primary mediators of its biotransformation.

In the context of drug discovery, this compound has been leveraged as a scaffold for designing novel analogs with enhanced selectivity and reduced side effects. A 2024 preprint on bioRxiv detailed a high-throughput screening campaign that identified several derivatives with promising activity against treatment-resistant depression. These findings underscore the compound's versatility and the need for continued research to unlock its full therapeutic potential while addressing safety concerns.

In conclusion, N-Methyl-1-phenylethanamine hydrochloride (CAS: 10408-89-6) remains a pivotal compound in chemical biology and pharmaceutical research. Its dual role as a synthetic intermediate and a pharmacologically active agent warrants further exploration, particularly in optimizing its therapeutic index and mitigating risks associated with misuse. Collaborative efforts between chemists, pharmacologists, and regulatory bodies will be essential to harness its benefits responsibly.

10408-89-6 (N-Methyl-1-phenylethanamine hydrochloride) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:10408-89-6)N-Methyl-1-phenylethanamine hydrochloride
A896291
Purity:99%
Quantity:5g
Price ($):233.0
Email