Cas no 104-32-5 (Propamidine)

Propamidine structure
Propamidine structure
Product Name:Propamidine
CAS No:104-32-5
MF:C17H20N4O2
MW:312.366303443909
CID:35268
PubChem ID:64949
Update Time:2025-07-21

Propamidine Chemical and Physical Properties

Names and Identifiers

    • Propamidine
    • 4,4'-(1,3-Propanediylbis(oxy))bisbenzenecarboximidamide
    • 4,4’-(trimethylenedioxy)dibenzamidine
    • 4,4’-[1,3-propanediylbis(oxy)]bis[benzenecarboximidamide]
    • 4,4’-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide
    • 4,4'-Propandiyldioxy-bis-benzamidin
    • 4,4'-propanediyldioxy-bis-benzamidine
    • Brolene
    • DAPP
    • α,ω-(4,4’-diamidinodiphenoxy)propane
    • 4,4'-(1,3-Propanediyl)bis(oxy)bisbenzamidine
    • 4,4'-[1,3-Propanediylbis(oxy)]dibenzenecarboximidamide
    • 4,4'-[1,3-Propanediylbis(oxy)]bis(benzenecarbimidamide)
    • BenzenecarboxiMidaMide,4,4'-[1,3-propanediylbis(oxy)]bis-
    • 4,4'-(TRIMETHYLEDEDIOXY)DIBENZAMIDINE
    • M&B 782 [AS ISETHIONATE]
    • 4,4'-Diamidino-1,3-diphenoxypropane dihydrochloride
    • 4-(3-(4-(Amino(imino)methyl)phenoxy)propoxy)benzenecarboximidamide
    • AKOS015854464
    • NCGC00183108-01
    • Benzenecarboximidamide, {4,4'-[1,3-propanediylbis(oxy)]bis-,} dihydrochloride
    • 4,4'-(propane-1,3-diylbis(oxy))dibenzimidamide
    • CS-0119541
    • Propamidina
    • UNII-G20G12V769
    • PROPAMIDINE [WHO-DD]
    • PROPAMIDINE [INN]
    • PROPAMIDINE [MI]
    • D07205
    • Propamidine (INN)
    • 4,4'-[1,3-Propanediylbis(oxy)]bisbenzenecarboximidamide-
    • DTXSID6048674
    • Propamidina [INN-Spanish]
    • NSC33297
    • Propamide dihydrochloride
    • PROPAMIDINE CHLORIDE
    • GNF-PF-3839
    • G20G12V769
    • Panamidin
    • 4,4'-[propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide)
    • Q1240692
    • CHEBI:87462
    • NS00041349
    • Propamidinum [INN-Latin]
    • 6275-69-0
    • 4-[3-(4-carbamimidoylphenoxy)propoxy]benzamidine
    • DTXCID6028600
    • Tox21_113051
    • BDBM50368092
    • 104-32-5
    • DB13296
    • Benzenecarboximidamide, 4,4'-[1,3-propanediylbis(oxy)]bis-
    • 4-[3-(4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide
    • WTFXJFJYEJZMFO-UHFFFAOYSA-N
    • 4,4'-(1,3-PROPANEDIYLBIS(OXY)BIS(BENZENECARBOXIMIDAMIDE)
    • 4,4'-(1,3-Propanediylbis(oxy))bis-benzenecarboximidamide
    • p,p'-(Trimethylenedioxy)dibenzamidine-
    • M&B 782 FREE BASE
    • Propamidinum
    • 4,4'-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide
    • EINECS 203-195-2
    • Propamidine [INN:BAN:DCF]
    • 4,4'-(Trimethylenedioxy)dibenzamidine
    • 1,3-BIS(AMIDINOPHENOXY)PROPANE
    • CHEMBL23013
    • CAS-104-32-5
    • SCHEMBL231060
    • M&B-782 FREE BASE
    • HY-130402B
    • Propamidina (INN-Spanish)
    • 4,4'(Trimethylenedioxy)dibenzamidine
    • S01AX15
    • 1,3-di-(4-amidinophenoxy)propane
    • DAPP-Br
    • 203-195-2
    • M&B 782 (AS ISETHIONATE)
    • FP151543
    • D08AC03
    • 1,3-di-(p-amidinophenoxymethyl)-propane
    • DAPP-H
    • 1,3-bis(p-amidinophenoxy)propane
    • 4,4'-(propane-1,3-diylbis(oxy))di(benzene-1-carboximidamide)
    • 4,4'(1,3Propanediylbis(oxy))bisbenzenecarboximidamide
    • 4-[3-(4-carbamimidoylphenoxy)propoxy]benzene-1-carboximidamide
    • 4-(3-(4-carbamimidoylphenoxy)propoxy)benzene-1-carboximidamide
    • Propamidinum (INN-Latin)
    • MDL： MFCD00866601
    • Inchi： 1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21)
    • InChI Key： WTFXJFJYEJZMFO-UHFFFAOYSA-N
    • SMILES： O(C1C=CC(C(=N)N)=CC=1)CCCOC1C=CC(C(=N)N)=CC=1

Computed Properties

  • Exact Mass: 312.15900
  • Monoisotopic Mass: 312.158626
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 23
  • Rotatable Bond Count: 8
  • Complexity: 350
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 1.8
  • Topological Polar Surface Area: 118

Experimental Properties

  • Density: 1.25
  • Boiling Point: 497.3°Cat760mmHg
  • Flash Point: 254.6°C
  • Refractive Index: 1.608
  • PSA: 118.20000
  • LogP: 3.70270

Propamidine Customs Data

  • HS CODE：2925290012
  • Customs Data：

    China Customs Code:

    2925290012

    Overview:

    2925290012 semiamitraz \Varamidine\propamidine .Regulatory conditions:S(Import and Export Pesticide Registration Certificate).VAT:17.0%.Tax refund rate:9.0%.Minimum tariff:6.5%.general tariff:30.0%

    Summary:

    2925290012 (e)-3-(((dimethylamino)methylene)amino)phenyl methylcarbamate.supervision conditions:s(import or export registration certificate for pesticides).VAT:17.0%.tax rebate rate:9.0%.MFN tarrif:6.5%.general tariff:30.0%

Propamidine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
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 104-32-5
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 $ 90.00 2022-06-03
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P014627-5mg
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 104-32-5
5mg
 $ 135.00 2022-06-03
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P014627-10mg
Propamidine
 104-32-5
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 $ 220.00 2022-06-03

Propamidine Suppliers

Suzhou Senfeida Chemical Co., Ltd
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(CAS:104-32-5)Propamidine
Order Number:sfd22047
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:39
Price ($):discuss personally

Propamidine Related Literature

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Additional information on Propamidine

Propamidine and CAS No. 104-32-5: A Comprehensive Overview in Modern Chemical Biology

The compound with the chemical identifier CAS No. 104-32-5 is a key molecule in the realm of chemical biology, particularly noted for its applications in pharmaceutical research and development. The product name Propamidine, derived from this CAS number, refers to a heterocyclic organic compound that has garnered significant attention due to its versatile chemical properties and potential biological activities.

Propamidine, classified under the CAS No. 104-32-5, is an imidazolidine derivative that exhibits notable stability and reactivity, making it a valuable intermediate in synthetic chemistry. Its molecular structure, characterized by a six-membered ring containing two nitrogen atoms, contributes to its unique interaction with biological targets. This structural feature has been leveraged in the development of various pharmacological agents, where Propamidine serves as a foundational building block.

In recent years, Propamidine has been the subject of extensive research aimed at uncovering its therapeutic potential. One of the most compelling areas of investigation has been its role in antimicrobial applications. Studies have demonstrated that Propamidine derivatives exhibit potent activity against a range of bacterial and fungal pathogens. This has been attributed to its ability to disrupt essential cellular processes, such as DNA replication and protein synthesis, thereby inhibiting microbial growth.

The mechanistic insights into Propamidine's antimicrobial properties have been further refined through advanced spectroscopic techniques and computational modeling. These studies have revealed that the compound interacts with specific enzymatic targets within microbial cells, leading to irreversible inhibition. Such findings have not only enhanced our understanding of Propamidine's mode of action but also provided a framework for designing novel antimicrobial agents with improved efficacy and reduced resistance profiles.

Beyond its antimicrobial applications, Propamidine has also shown promise in other therapeutic domains. For instance, researchers have explored its potential as an anti-inflammatory agent, leveraging its ability to modulate immune responses. Preclinical studies have indicated that Propamidine derivatives can attenuate inflammatory cytokine production, thereby mitigating chronic inflammatory conditions. These findings highlight the compound's broad pharmacological spectrum and its potential for multifaceted therapeutic interventions.

The synthesis of Propamidine derivatives has been optimized to enhance their biological activity while minimizing toxic side effects. Advances in synthetic methodologies have enabled the production of highly pure and structurally diverse derivatives, which can be tailored for specific biological targets. Techniques such as combinatorial chemistry and high-throughput screening have accelerated the discovery process, allowing for rapid identification of lead compounds with optimized properties.

In the context of drug development, Propamidine has been integrated into various pipelines for treating infectious diseases and inflammatory disorders. Its structural versatility allows for seamless incorporation into larger molecular frameworks, enhancing drug-like properties such as solubility, bioavailability, and metabolic stability. Collaborative efforts between academic institutions and pharmaceutical companies have further propelled the translation of Propamidine-based compounds from laboratory research to clinical trials.

The latest research trends indicate a growing interest in harnessing Propamidine's chemical diversity for next-generation therapeutics. Innovations in medicinal chemistry have led to the development of prodrugs and targeted delivery systems that enhance the efficacy of Propamidine derivatives. These advancements are poised to revolutionize treatment strategies for a wide array of diseases by improving drug delivery and minimizing off-target effects.

As our understanding of Propamidine's biological activities continues to expand, so does its potential in addressing unmet medical needs. The integration of cutting-edge technologies such as artificial intelligence (AI) and machine learning (ML) has further accelerated the discovery pipeline by predicting novel drug candidates derived from Propamidine scaffolds. Such interdisciplinary approaches are fostering innovation and paving the way for breakthroughs in chemical biology.

In conclusion, Propamidine (CAS No. 104-32-5) represents a cornerstone compound in modern chemical biology with far-reaching implications for pharmaceutical research and development. Its unique structural features and versatile biological activities make it an indispensable tool for designing innovative therapeutics targeting infectious diseases, inflammation, and other complex disorders. As ongoing research continues to unravel new facets of its potential, Propamidine is set to remain at the forefront of scientific discovery in the years to come.

104-32-5 (Propamidine) Related Products

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Suzhou Senfeida Chemical Co., Ltd
(CAS:104-32-5)Propamidine
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Purity:99.9%
Quantity:200kg
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