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  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
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  Gerald J. Meyer,Leif Hammarstr?m Chem. Sci., 2020,11, 3460-3473
• 4. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

Ethyl 2-acetylbenzoate (CAS No. 103935-10-0): A Comprehensive Overview

Ethyl 2-acetylbenzoate, with the chemical formula C₁₀H₁₀O₃ and the CAS number 103935-10-0, is a versatile organic compound that has garnered significant attention in the field of organic chemistry and pharmaceutical research. This ester, derived from benzoic acid and ethanol, exhibits a variety of applications ranging from flavoring agents to potential pharmaceutical intermediates. Its unique structural properties make it a valuable building block in synthetic chemistry, particularly in the development of more complex molecules.

The compound is characterized by a benzene ring substituted with an acetyl group at the second position and an ethoxy group at the one position. This structural arrangement imparts distinct chemical reactivity, making it a candidate for various chemical transformations. In recent years, the study of Ethyl 2-acetylbenzoate has been further propelled by its potential role in medicinal chemistry, where its derivatives have been explored for their pharmacological properties.

One of the most intriguing aspects of Ethyl 2-acetylbenzoate is its role as a precursor in the synthesis of more complex natural products and pharmaceuticals. Researchers have leveraged its reactivity to develop novel compounds with potential therapeutic applications. For instance, studies have shown that derivatives of Ethyl 2-acetylbenzoate can exhibit anti-inflammatory and analgesic properties, making them promising candidates for further development into new drugs.

The chemical synthesis of Ethyl 2-acetylbenzoate typically involves the esterification of benzoic acid with ethanol under acidic conditions. This reaction is well-documented and can be optimized for high yields and purity. The ease of synthesis makes it an attractive compound for both academic research and industrial applications. Additionally, advances in green chemistry have led to the development of more sustainable methods for producing Ethyl 2-acetylbenzoate, which aligns with global efforts to reduce environmental impact.

In recent years, there has been a growing interest in exploring the biological activity of Ethyl 2-acetylbenzoate and its derivatives. Computational studies have suggested that certain modifications to its structure could enhance its bioavailability and target specificity. These findings have opened up new avenues for drug discovery, particularly in the treatment of chronic inflammatory diseases and pain management.

The compound's stability under various conditions also makes it a valuable tool in chemical research. It remains stable under standard storage conditions, allowing for long-term investigations without degradation. This stability is crucial for experimental consistency and reproducibility in scientific studies.

Ethyl 2-acetylbenzoate has also found applications in the fragrance and flavor industry due to its pleasant aroma and taste profile. Its derivatives are used to create synthetic fragrances that mimic natural scents, contributing to the development of perfumes, soaps, and other consumer products. The compound's versatility underscores its importance across multiple industries.

The future prospects of Ethyl 2-acetylbenzoate are promising, with ongoing research aimed at uncovering new applications and improving synthetic methodologies. As our understanding of organic chemistry continues to evolve, it is likely that this compound will play an even greater role in both academic research and industrial processes.

• 134098-88-7(Benzoic acid, 2-benzoyl-3,6-dimethyl-, propyl ester)
• 604-61-5(Ethyl 2-(Phenylcarbonyl)benzoate)
• 134098-87-6(Benzoic acid, 2-benzoyl-4,5-dimethyl-, ethyl ester)
• 134098-89-8(Benzoic acid, 2-(2,4,6-trimethylbenzoyl)-, ethyl ester)
• 6198-43-2(Benzoic acid,2-(2,4,6-trimethylbenzoyl)-, anhydride with 2-(2,4,6-trimethylbenzoyl)benzoicacid)
• 604-62-6(Benzoic acid,2-benzoyl-, propyl ester)
• 1077-79-8(Methyl 2-Acetylbenzoate)
• 51986-91-5(1,2-Benzenedicarboxylicacid, 4,4'-carbonylbis-, 2,2'-diethyl ester (9CI))
• 85409-81-0(1,2-Ethylene 2-benzoyl-5-methylbenzoate)
• 134098-86-5(Benzoic acid, 2-(2,4-dimethylbenzoyl)-, ethyl ester)