Cas no 103054-24-6 (Methyl 2-2-(2-Chloroacetamido)-1,3-thiazol-4-ylacetate)

Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate is a specialized organic compound featuring a thiazole core functionalized with a chloroacetamido group and an ester moiety. This structure imparts reactivity suitable for further synthetic modifications, particularly in pharmaceutical and agrochemical applications. The chloroacetamido group enables nucleophilic substitution reactions, while the ester functionality offers versatility for hydrolysis or transesterification. Its thiazole scaffold is notable for contributing to bioactive properties, making it valuable in the development of heterocyclic compounds. The product is characterized by high purity and stability under standard storage conditions, ensuring consistent performance in research and industrial processes. Proper handling is advised due to its potential reactivity.
Methyl 2-2-(2-Chloroacetamido)-1,3-thiazol-4-ylacetate structure
103054-24-6 structure
Product Name:Methyl 2-2-(2-Chloroacetamido)-1,3-thiazol-4-ylacetate
CAS No:103054-24-6
MF:C8H9ClN2O3S
MW:248.686659574509
CID:3105757
PubChem ID:2414268
Update Time:2025-11-02

Methyl 2-2-(2-Chloroacetamido)-1,3-thiazol-4-ylacetate Chemical and Physical Properties

Names and Identifiers

    • methyl {2-[(chloroacetyl)amino]-1,3-thiazol-4-yl}acetate
    • EN300-05331
    • AKOS000118530
    • 103054-24-6
    • methyl 2-[2-(2-chloroacetamido)-1,3-thiazol-4-yl]acetate
    • methyl 2-[2-[(2-chloroacetyl)amino]-1,3-thiazol-4-yl]acetate
    • methyl2-[2-(2-chloroacetamido)-1,3-thiazol-4-yl]acetate
    • Z56900784
    • Methyl 2-2-(2-Chloroacetamido)-1,3-thiazol-4-ylacetate
    • Inchi: 1S/C8H9ClN2O3S/c1-14-7(13)2-5-4-15-8(10-5)11-6(12)3-9/h4H,2-3H2,1H3,(H,10,11,12)
    • InChI Key: FGTQVOQSRPCNHN-UHFFFAOYSA-N
    • SMILES: ClCC(NC1=NC(=CS1)CC(=O)OC)=O

Computed Properties

  • Exact Mass: 248.002241g/mol
  • Monoisotopic Mass: 248.002241g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 5
  • Complexity: 252
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 248.69g/mol
  • XLogP3: 0.9
  • Topological Polar Surface Area: 96.5?2

Methyl 2-2-(2-Chloroacetamido)-1,3-thiazol-4-ylacetate Pricemore >>

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Additional information on Methyl 2-2-(2-Chloroacetamido)-1,3-thiazol-4-ylacetate

Comprehensive Guide to Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate (CAS No. 103054-24-6)

Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate (CAS No. 103054-24-6) is a specialized chemical compound widely used in pharmaceutical and agrochemical research. This thiazole derivative is known for its unique structural properties, making it a valuable intermediate in the synthesis of bioactive molecules. With the increasing demand for novel drug candidates and crop protection agents, this compound has garnered significant attention in recent years.

The molecular structure of Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate features a thiazole ring core, which is a common motif in many biologically active compounds. The presence of the chloroacetamido group enhances its reactivity, allowing it to participate in various chemical transformations. Researchers often utilize this compound in the development of antimicrobial agents, anti-inflammatory drugs, and herbicides, aligning with current trends in sustainable agriculture and healthcare.

One of the key advantages of Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate is its versatility in synthetic chemistry. It serves as a building block for the preparation of more complex molecules, particularly in heterocyclic chemistry. The compound's stability under various reaction conditions makes it a preferred choice for laboratories focusing on medicinal chemistry and drug discovery. Recent studies have highlighted its potential in addressing antibiotic resistance, a pressing global health concern.

In the agrochemical sector, Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate is explored for its role in developing eco-friendly pesticides. As the industry shifts toward sustainable practices, this compound's ability to target specific pests without harming beneficial organisms is highly valued. Its application in crop protection formulations is being investigated to meet the growing demand for food security solutions.

The synthesis of Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate typically involves multi-step organic reactions, including amide coupling and esterification. Researchers optimize these processes to achieve high yields and purity, ensuring the compound's suitability for further applications. Advanced techniques such as HPLC and NMR spectroscopy are employed to characterize and validate its structure, meeting stringent quality standards.

From a commercial perspective, the demand for Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate is driven by its relevance in pharmaceutical intermediates and agrochemical research. Suppliers and manufacturers emphasize its high purity and consistent performance, catering to the needs of academic institutions, contract research organizations (CROs), and industrial laboratories. The compound's CAS No. 103054-24-6 is frequently referenced in procurement databases and scientific literature.

Safety and handling guidelines for Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate emphasize standard laboratory precautions. Proper storage conditions, such as maintaining a cool, dry environment, are recommended to preserve its stability. Researchers are advised to consult Material Safety Data Sheets (MSDS) for detailed information on handling and disposal, ensuring compliance with regulatory requirements.

Looking ahead, the potential applications of Methyl 2-[2-(2-Chloroacetamido)-1,3-thiazol-4-yl]acetate continue to expand. Innovations in green chemistry and catalysis may further enhance its utility in sustainable drug development and crop protection. As scientific advancements progress, this compound is poised to play a pivotal role in addressing some of the most critical challenges in healthcare and agriculture.

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