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  Grégoire Sieg,Igor Müller,Kilian Wei?er,C. Gunnar Werncke Chem. Sci. 2022 13 13872
• 2. Recent advances in synthesis of stilbene derivatives via cross-coupling reaction
  Fatemeh Doraghi,Faeze Yousefnejad,Soghra Farzipour,Seyedeh Pegah Aledavoud,Bagher Larijani,Mohammad Mahdavi Org. Biomol. Chem. 2023 21 1846
• 3. Activation of hydrogen peroxide by p-nitrophenyl chloroformate. Indication for in situ formation of carbon trioxide and evidence for singlet oxygen generation by the chloride-catalysed decomposition of hydrogen peroxide in acidic solution
  Carsten Bender,Hans-Dieter Brauer p-nitrophenyl chloroformate. Indication for in situ formation of carbon trioxide and evidence for singlet oxygen generation by the chloride-catalysed decomposition of hydrogen peroxide in acidic solution. Carsten Bender Hans-Dieter Brauer J. Chem. Soc. Perkin Trans. 2 2000 535
• 4. A catalyzed E/Z isomerization mechanism of stilbene using para-benzoquinone as a triplet sensitizer
  Kaho Nakatani,Hirofumi Sato,Ryoichi Fukuda Phys. Chem. Chem. Phys. 2022 24 1712
• 5. Breaking the bottleneck: stilbene as a model compound for optimizing 6π e? photocyclization efficiency
  Joshua Seylar,Dmytro Stasiouk,Davide L. Simone,Vikas Varshney,James E. Heckler,Ruel McKenzie RSC Adv. 2021 11 6504

• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes Stilbenes
• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Trans-Stilbene: A Comprehensive Overview

Trans-stilbene (CAS No. 103-30-0) is a naturally occurring organic compound with the chemical formula C₁₄H₁₂. It is a derivative of stilbene, a class of compounds characterized by two phenyl groups connected by a double bond. The trans configuration refers to the spatial arrangement of the phenyl groups, which are on opposite sides of the double bond. This compound has garnered significant attention in recent years due to its diverse applications in chemistry, pharmacology, and materials science.

The structure of trans-stilbene is relatively simple, consisting of two benzene rings connected by a double bond. This arrangement imparts unique electronic and optical properties to the molecule. Recent studies have explored the potential of stilbene derivatives in photovoltaic applications, where their ability to absorb light and facilitate electron transfer makes them promising candidates for next-generation solar cells. Researchers have also investigated the use of stilbene-based materials in organic light-emitting diodes (OLEDs), where their high fluorescence quantum yield and stability are advantageous.

One of the most notable advancements in trans-stilbene research is its role in drug discovery. Scientists have synthesized various stilbene derivatives with tailored pharmacological properties, including anti-inflammatory, antioxidant, and anticancer activities. For instance, a 2023 study published in *Nature Communications* demonstrated that certain stilbene analogs exhibit potent inhibitory effects on tumor growth by targeting specific signaling pathways. These findings have opened new avenues for the development of targeted therapies.

In addition to its pharmacological applications, trans-stilbene has found utility in the field of materials science. Researchers have developed stilbene-based polymers with high thermal stability and mechanical strength, making them suitable for use in high-performance composites. A recent breakthrough involves the synthesis of stilbene-containing copolymers that exhibit excellent electrical conductivity, paving the way for their integration into flexible electronics.

The synthesis of trans-stilbene has also been optimized in recent years. Traditional methods involve the coupling of phenyl groups via palladium-catalyzed cross-coupling reactions. However, advancements in catalytic chemistry have enabled more efficient and selective routes to prepare stilbene derivatives. For example, a 2022 study reported the use of a novel ruthenium catalyst to synthesize stilbene analogs with unprecedented yields and purity.

Despite its numerous applications, the environmental impact of trans-stilbene remains a topic of interest. Studies have shown that certain stilbene derivatives can undergo photochemical degradation under UV light, reducing their persistence in the environment. This property is particularly relevant for applications where long-term stability is not desired, such as in biodegradable polymers.

In conclusion, trans-stilbene (CAS No. 103-30-0) stands as a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical structure and tunable properties make it an invaluable tool for researchers and industry professionals alike. As ongoing studies continue to uncover new uses and improvements in its synthesis and application, trans-stilbene is poised to play an even greater role in shaping future technological and medical advancements.

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• 920985-20-2(Benzene, 1,3,5-tris[2-(3,5-dimethylphenyl)ethenyl]-)
• 1860-17-9( )
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• 918538-56-4(Phenyl, 2-[(1E)-2-phenylethenyl]-)
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