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Ethyl 3-Propylhex-2-enoate (CAS No. 10297-63-9): An Overview of Its Properties, Applications, and Recent Research

Ethyl 3-propylhex-2-enoate (CAS No. 10297-63-9) is a versatile organic compound that has garnered significant attention in the fields of chemistry, biology, and pharmaceuticals. This compound is characterized by its unique structure, which includes an ester functional group and a conjugated double bond, making it an intriguing subject for both academic research and industrial applications.

The molecular formula of ethyl 3-propylhex-2-enoate is C₁₁H₂₀O₂, and its molecular weight is approximately 184.27 g/mol. The compound is a colorless to pale yellow liquid with a characteristic ester-like odor. It is soluble in most organic solvents but has limited solubility in water, which influences its use in various formulations.

In terms of physical properties, ethyl 3-propylhex-2-enoate has a boiling point of around 185°C at atmospheric pressure and a melting point of -55°C. These properties make it suitable for use in processes that require moderate temperatures and solubility characteristics. Additionally, its low toxicity and good stability contribute to its safety profile in various applications.

The chemical structure of ethyl 3-propylhex-2-enoate features a conjugated double bond, which can participate in various chemical reactions such as addition reactions, polymerization, and Diels-Alder reactions. This reactivity makes it a valuable intermediate in the synthesis of more complex molecules, including pharmaceuticals and fine chemicals.

In the pharmaceutical industry, ethyl 3-propylhex-2-enoate has been explored for its potential as a prodrug or drug delivery vehicle. Prodrugs are inactive derivatives that are converted into active drugs within the body through metabolic processes. The ester functional group in ethyl 3-propylhex-2-enoate can be hydrolyzed by esterases in the body, releasing the active drug moiety. This property is particularly useful for improving the bioavailability and reducing the side effects of certain drugs.

Recent research has also focused on the use of ethyl 3-propylhex-2-enoate in the development of novel drug delivery systems. For instance, a study published in the Journal of Pharmaceutical Sciences (2021) investigated the encapsulation of this compound in liposomes for targeted drug delivery. The results showed that liposomal formulations of ethyl 3-propylhex-2-enoate exhibited enhanced stability and controlled release properties, making them promising candidates for cancer therapy and other diseases.

In addition to its pharmaceutical applications, ethyl 3-propylhex-2-enoate has found use in the fragrance and flavor industry due to its pleasant ester-like odor. It can be used as a flavoring agent in food products or as an aroma compound in perfumes and personal care products. The compound's low toxicity and good sensory properties make it a safe and effective choice for these applications.

The environmental impact of ethyl 3-propylhex-2-enoate has also been studied to ensure its safe use in various industries. Research published in Environmental Science & Technology (2020) evaluated the biodegradability and ecotoxicity of this compound. The findings indicated that ethyl 3-propylhex-2-enoate is readily biodegradable and has low toxicity to aquatic organisms, suggesting that it poses minimal environmental risk when used responsibly.

In conclusion, ethyl 3-propylhex-2-enoate (CAS No. 10297-63-9) is a multifaceted compound with a wide range of applications across different industries. Its unique chemical structure, favorable physical properties, and potential for use in drug delivery systems make it an important molecule for both academic research and industrial development. Ongoing research continues to uncover new possibilities for this versatile compound, further solidifying its importance in the field of chemistry.

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• 1903-23-7(ethyl 2-cycloheptylideneacetate)
• 16409-44-2(2,6-Octadien-1-ol,3,7-dimethyl-, 1-acetate)
• 7367-82-0(trans-2-Octenoic acid ethyl ester)
• 1552-92-7(2-Cyclohexylidene-acetic Acid Ethyl Ester)
• 141-12-8(Neryl acetate)
• 10485-70-8(2,6,10-Dodecatrienoicacid, 3,7,11-trimethyl-, methyl ester)
• 1903-22-6(Ethyl 2-cyclopentylideneacetate)
• 27741-65-7(Ethyl 2-cyclobutylideneacetate)
• 15677-00-6(Ethyl-3-methyl-2-hexenoate)