Cas no 1028479-47-1 ((4-Formyl-2-methoxyphenyl)boronic acid)

(4-Formyl-2-methoxyphenyl)boronic acid is a versatile boronic acid derivative widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its aldehyde and methoxy functional groups enhance reactivity and selectivity, making it valuable for constructing complex aromatic systems. The compound exhibits good stability under standard conditions, facilitating handling and storage. Its bifunctional nature allows for further derivatization, enabling applications in pharmaceuticals, agrochemicals, and material science. High purity grades ensure consistent performance in catalytic processes. The product is particularly useful in synthesizing intermediates for drug development and fine chemicals, where precise functional group compatibility is required. Proper handling under inert conditions is recommended to maintain integrity.
(4-Formyl-2-methoxyphenyl)boronic acid structure
1028479-47-1 structure
Product Name:(4-Formyl-2-methoxyphenyl)boronic acid
CAS No:1028479-47-1
MF:C8H9BO4
MW:179.965662717819
MDL:MFCD11856026
CID:1036643
Update Time:2025-10-28

(4-Formyl-2-methoxyphenyl)boronic acid Chemical and Physical Properties

Names and Identifiers

    • (4-Formyl-2-methoxyphenyl)boronic acid
    • 4-FORMYL-2-METHOXYPHENYLBORONIC ACID
    • AM80883
    • FCH1150752
    • 3-Methoxy-4-(dihydroxyboryl)benzaldehyde
    • (4-Formyl-2-methoxy-phenyl)boronic acid
    • OR350182
    • BC001744
    • ST2401554
    • AB0036356
    • AX8218084
    • Y3552
    • Boronic acid, B-(4-formyl-2-methoxyphenyl)-
    • MDL: MFCD11856026
    • Inchi: 1S/C8H9BO4/c1-13-8-4-6(5-10)2-3-7(8)9(11)12/h2-5,11-12H,1H3
    • InChI Key: PQECZCKVUFXDGP-UHFFFAOYSA-N
    • SMILES: O(C)C1C=C(C=O)C=CC=1B(O)O

Computed Properties

  • Exact Mass: 180.05900
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 174
  • Topological Polar Surface Area: 66.8

Experimental Properties

  • Boiling Point: 400.7±55.0°C at 760 mmHg
  • PSA: 66.76000
  • LogP: -0.81250

(4-Formyl-2-methoxyphenyl)boronic acid Security Information

(4-Formyl-2-methoxyphenyl)boronic acid Customs Data

  • HS CODE:2931900090
  • Customs Data:

    China Customs Code:

    2931900090

    Overview:

    2931900090. Other organic-Inorganic compound. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:6.5%. general tariff:30.0%

    Summary:

    2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

(4-Formyl-2-methoxyphenyl)boronic acid Pricemore >>

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(4-Formyl-2-methoxyphenyl)boronic acid Production Method

Additional information on (4-Formyl-2-methoxyphenyl)boronic acid

Comprehensive Guide to (4-Formyl-2-methoxyphenyl)boronic acid (CAS No. 1028479-47-1): Properties, Applications, and Market Insights

(4-Formyl-2-methoxyphenyl)boronic acid (CAS No. 1028479-47-1) is a specialized boronic acid derivative widely used in organic synthesis, pharmaceutical research, and material science. This compound, featuring both a formyl group and a methoxy group on its phenyl ring, is valued for its versatility in Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic chemistry. Researchers and industries frequently search for "boronic acid applications" or "CAS 1028479-47-1 supplier," highlighting its growing relevance in drug discovery and advanced material development.

The molecular structure of (4-Formyl-2-methoxyphenyl)boronic acid enables its role as a key intermediate in synthesizing complex molecules. Its boron-containing functional group facilitates the formation of carbon-carbon bonds, making it indispensable for creating biaryl compounds used in OLEDs, liquid crystals, and bioactive molecules. Recent trends in "green chemistry" and "sustainable synthesis" have further amplified interest in this compound, as it often reduces the need for toxic catalysts in coupling reactions.

In pharmaceutical applications, 1028479-47-1 serves as a building block for protease inhibitors and kinase-targeted drugs, aligning with the surge in searches for "boronic acid in drug design." Its unique electronic properties, influenced by the methoxy substituent, enhance binding affinity in drug-receptor interactions. Laboratories optimizing "high-throughput screening" protocols also prioritize this compound due to its stability and compatibility with automated synthesis platforms.

The global market for (4-Formyl-2-methoxyphenyl)boronic acid reflects its expanding applications, with suppliers emphasizing "high-purity boronic acids" for research-grade and industrial-scale use. Analytical techniques like HPLC and NMR ensure quality control, addressing frequent queries about "CAS 1028479-47-1 characterization." Storage recommendations typically suggest anhydrous conditions to preserve its reactivity, a detail often sought in "boronic acid handling guidelines."

Emerging studies explore its utility in covalent organic frameworks (COFs) and sensor materials, responding to trending searches like "boronic acid sensors for glucose detection." As industries seek alternatives to conventional materials, this compound’s role in smart coatings and molecular electronics continues to gain traction. Regulatory-compliant synthesis methods (e.g., REACH) further bolster its adoption in European and North American markets.

For researchers investigating "structure-activity relationships," the formyl group in 1028479-47-1 offers a handle for further derivatization, enabling tailored modifications. This adaptability aligns with the demand for "custom boronic acid derivatives" in academic and industrial settings. Recent patents highlight its use in photocatalysis and metal-organic frameworks (MOFs), areas generating significant scientific interest.

In summary, (4-Formyl-2-methoxyphenyl)boronic acid (CAS No. 1028479-47-1) bridges multiple disciplines, from medicinal chemistry to advanced materials. Its synergy with cutting-edge research themes—such as "click chemistry" and "precise molecular editing"—ensures its enduring relevance. Suppliers and researchers alike benefit from understanding its multifaceted applications, quality benchmarks, and evolving market dynamics.

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