Cas no 10258-54-5 (2-methoxyethyl 2-cyanoacetate)

2-Methoxyethyl 2-cyanoacetate is a versatile ester compound widely used in organic synthesis and pharmaceutical applications. Its key advantages include a reactive cyanoacetate group, which facilitates condensation and nucleophilic addition reactions, making it valuable in the preparation of heterocyclic compounds and fine chemicals. The 2-methoxyethyl moiety enhances solubility in polar solvents, improving reaction efficiency. This compound is particularly useful in Knoevenagel condensations and as a precursor for agrochemicals and dyes. Its stability under standard conditions and compatibility with various reagents further contribute to its utility in research and industrial processes. Proper handling is advised due to its potential irritant properties.
2-methoxyethyl 2-cyanoacetate structure
2-methoxyethyl 2-cyanoacetate structure
Product Name:2-methoxyethyl 2-cyanoacetate
CAS No:10258-54-5
MF:C6H9NO3
MW:143.140561819077
MDL:MFCD00071550
CID:48482
PubChem ID:25106
Update Time:2025-05-20

2-methoxyethyl 2-cyanoacetate Chemical and Physical Properties

Names and Identifiers

    • 2-Methoxyethyl cyanoacetate
    • Aceticacid,cyano-,2-methoxyethylester
    • cyano-aceticaci2-methoxyethylester
    • CYANOACETIC ACID 2-METHOXYETHYL ESTER
    • METHOXY ETHYL CYANOACETATE
    • 2-Methoxyethylcyanacetat
    • 2-methoxyethyl 2-cyanoacetate
    • Aceticacid, cyano-, 2-methoxyethyl ester (7CI,8CI,9CI)
    • Ethanol, 2-methoxy-,cyanoacetate (8CI)
    • Cyanoacetic acid, b-methoxyethyl ester
    • 2-MECA
    • 3-Oxo-3-(2-methoxyethoxy)propanenitrile
    • 2-Cyanoacetic acid 2-methoxyethyl ester
    • Cyanoacetic acid,2-methoxyethyl ester
    • Cyanoacetic acid, .beta.-methoxyethyl ester
    • Tox21_300797
    • SCHEMBL755188
    • MFCD00071550
    • BCP12767
    • 2-Methoxyethyl cyanoacetate, 98%
    • 10258-54-5
    • W-110264
    • F81534
    • NCGC00248171-01
    • NS00023161
    • 2-methoxyethyl2-cyanoacetate
    • FT-0612843
    • DTXSID0038831
    • UNII-UT9YIO537F
    • BRN 1766090
    • CHEMBL3186943
    • AKOS000120189
    • CAS-10258-54-5
    • Q27291265
    • CYANOACETIC ACID, 2-METHOXYETHYL ESTER
    • EN300-20676
    • A896755
    • Z104479724
    • methoxyethyl cyanoacetate
    • ?2-Methoxyethyl cyanoacetate
    • DTXCID8018831
    • NCGC00254701-01
    • ACETIC ACID, CYANO-, 2-METHOXYETHYL ESTER
    • 2-METHOXYETHYLCYANOACETATE
    • EINECS 233-597-3
    • SGLKIEOMYXTGBH-UHFFFAOYSA-N
    • AS-66036
    • Acetic acid, 2-cyano-, 2-methoxyethyl ester
    • UT9YIO537F
    • ETHANOL, 2-METHOXY-, CYANOACETATE
    • 2-Methoxyethyl cyanoacetate, Lonza quality, >=99.0% (GC)
    • CYANOACETIC ACID, BETA-METHOXYETHYL ESTER
    • MDL: MFCD00071550
    • Inchi: 1S/C6H9NO3/c1-9-4-5-10-6(8)2-3-7/h2,4-5H2,1H3
    • InChI Key: SGLKIEOMYXTGBH-UHFFFAOYSA-N
    • SMILES: O(C(CC#N)=O)CCOC
    • BRN: 1766090

Computed Properties

  • Exact Mass: 143.05800
  • Monoisotopic Mass: 143.058243
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 5
  • Complexity: 146
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: -0.1
  • Topological Polar Surface Area: 59.3

Experimental Properties

  • Color/Form: Colorless yellow liquid
  • Density: 1.127?g/mL?at 25?°C(lit.)
  • Boiling Point: 98-100?°C/1?mmHg(lit.)
  • Flash Point: Degrees Fahrenheit:235.4°F
    Degrees Celsius:113°C
  • Refractive Index: n20/D 1.434(lit.)
  • Solubility: 745g/l
  • PSA: 59.32000
  • LogP: 0.08968
  • Solubility: Soluble in water

2-methoxyethyl 2-cyanoacetate Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H315-H319-H335
  • Warning Statement: P261-P305+P351+P338
  • Hazardous Material transportation number:3276
  • WGK Germany:1
  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26-S36/37/39
  • RTECS:AG4350000
  • Hazardous Material Identification: Xi
  • PackingGroup:III
  • TSCA:Yes
  • Safety Term:S26;S36/37/39
  • Packing Group:III
  • Packing Group:III
  • Risk Phrases:R36/37/38
  • Storage Condition:Store below +30°C.

2-methoxyethyl 2-cyanoacetate Customs Data

  • HS CODE:2926909090
  • Customs Data:

    China Customs Code:

    2926909090

    Overview:

    2926909090 Other nitrile based compounds. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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2-methoxyethyl 2-cyanoacetate Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:10258-54-5)2-Methoxyethyl cyanoacetate
Order Number:sfd9982
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally

Additional information on 2-methoxyethyl 2-cyanoacetate

2-Methoxyethyl 2-Cyanoacetate: A Comprehensive Overview

2-Methoxyethyl 2-Cyanoacetate, also known by its CAS number 10258-54-5, is a versatile organic compound with significant applications in various fields of chemistry and chemical engineering. This compound has garnered attention due to its unique chemical properties and potential uses in drug design, polymer synthesis, and as an intermediate in organic synthesis. Recent advancements in synthetic methodologies and its biological applications have further highlighted its importance in modern chemistry.

The molecular structure of 2-Methoxyethyl 2-Cyanoacetate consists of a cyano group attached to a methyl-substituted acetate moiety, with a methoxyethyl group serving as the esterifying agent. This structure endows the compound with both nucleophilic and electrophilic reactivity, making it a valuable building block in organic synthesis. The presence of the cyano group also imparts unique electronic properties, which are exploited in various chemical transformations.

Recent studies have focused on the optimization of synthesis routes for 2-Methoxyethyl 2-Cyanoacetate. Researchers have explored environmentally friendly methods, such as catalytic asymmetric synthesis and microwave-assisted reactions, to enhance yield and reduce production costs. These advancements not only improve the scalability of the compound but also align with the growing demand for sustainable chemical processes.

In terms of biological applications, 2-Methoxyethyl 2-Cyanoacetate has shown promise as a precursor in drug design. Its ability to participate in various nucleophilic substitutions and condensation reactions makes it an ideal candidate for constructing bioactive molecules. For instance, recent research has demonstrated its utility in the synthesis of potential anticancer agents, where the cyano group plays a crucial role in modulating the pharmacokinetic properties of the resulting compounds.

The compound's role as an intermediate in polymer chemistry is another area of active investigation. Its ability to undergo polymerization under specific conditions has led to the development of novel polymeric materials with tailored properties. These materials exhibit potential applications in drug delivery systems and advanced coatings, where controlled release mechanisms are critical.

From an industrial perspective, 2-Methoxyethyl 2-Cyanoacetate's stability under various reaction conditions makes it a preferred choice for large-scale production processes. Its compatibility with a wide range of solvents and reagents further enhances its utility in diverse chemical industries.

In conclusion, 2-Methoxyethyl 2-Cyanoacetate, CAS No. 10258-54-5, stands out as a multifaceted compound with extensive applications across various domains of chemistry. Ongoing research continues to uncover new avenues for its use, underscoring its significance in both academic and industrial settings.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:10258-54-5)2-Methoxyethyl cyanoacetate
sfd9982
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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