• 1. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 2. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 3. Dissociative dynamics of O2 on Ag(110)?
  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
• 4. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 5. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Phenylpyridines

Introduction to 2-Methyl-4-phenylnicotinonitrile (CAS No. 102147-20-6)

2-Methyl-4-phenylnicotinonitrile is a chemical compound with the CAS registry number 102147-20-6. This compound belongs to the class of nitriles and is derived from nicotinic acid, a derivative of pyridine. The structure of 2-Methyl-4-phenylnicotinonitrile consists of a pyridine ring substituted with a methyl group at position 2 and a phenyl group at position 4, with a nitrile group (-CN) attached to the nitrogen atom of the pyridine ring.

The synthesis of 2-Methyl-4-phenylnicotinonitrile typically involves multi-step organic reactions, including Friedel-Crafts alkylation or acylation, followed by nitrile substitution or introduction. The compound has been studied for its potential applications in various fields, including pharmacology, agrochemicals, and materials science.

Recent studies have highlighted the biological activity of 2-Methyl-4-phenylnicotinonitrile, particularly its role as a lead compound in drug discovery. Researchers have explored its antimicrobial properties, which could make it a candidate for developing new antibiotics or antifungal agents. Additionally, the compound has shown promise in pesticide development, where it exhibits selective toxicity against agricultural pests without significant harm to non-target organisms.

In the field of materials science, 2-Methyl-4-phenylnicotinonitrile has been investigated for its potential as a building block in the synthesis of advanced materials, such as coordination polymers and metal-organic frameworks (MOFs). Its ability to coordinate with metal ions makes it a valuable component in constructing porous materials with applications in gas storage and catalysis.

The compound's chemical stability and reactivity make it an attractive substrate for further functionalization. For instance, researchers have explored its use in click chemistry reactions, where it serves as a precursor for constructing complex molecules with tailored properties. These studies underscore the versatility of 2-Methyl-4-phenylnicotinonitrile in both academic research and industrial applications.

From an environmental perspective, the degradation pathways of 2-Methyl-4-phenylnicotinonitrile have been studied to assess its potential impact on ecosystems. Research indicates that under certain conditions, the compound undergoes biodegradation, reducing its persistence in the environment. This information is crucial for evaluating its safety and sustainability in large-scale applications.

In summary, 2-Methyl-4-phenylnicotinonitrile (CAS No. 102147-20-6) is a versatile compound with diverse applications across multiple disciplines. Its unique chemical properties and biological activity make it a valuable subject for ongoing research and development efforts.

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