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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives m-Xylenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Xylenes m-Xylenes

Introduction to 2,6-Dimethylaniline-d9 (CAS No. 1021325-45-0)

2,6-Dimethylaniline-d9, with the CAS number 1021325-45-0, is a deuterated derivative of 2,6-dimethylaniline. This compound is widely used in various scientific and industrial applications, particularly in the fields of chemical synthesis, analytical chemistry, and pharmaceutical research. The deuterium atoms in this compound provide enhanced stability and unique spectroscopic properties, making it a valuable tool in both research and development.

The molecular formula of 2,6-Dimylaniline-d9 is C₈H₁₁N-d₉, and its molecular weight is approximately 147.18 g/mol. The presence of deuterium atoms (D) instead of hydrogen atoms (H) significantly alters the physical and chemical properties of the molecule. Deuterium has a higher atomic mass than hydrogen, which results in a more stable isotope and can influence the reactivity and spectroscopic behavior of the compound.

In analytical chemistry, 2,6-Dimethylaniline-d9 is often used as an internal standard in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. The deuterated form provides a distinct signal that can be easily distinguished from the non-deuterated analyte, enhancing the accuracy and reliability of quantitative analyses. This is particularly useful in complex mixtures where interference from other compounds can be a significant issue.

In pharmaceutical research, 2,6-Dimethylaniline-d9 has been utilized in the development of new drugs and drug delivery systems. Deuterated compounds are known to exhibit altered metabolic profiles compared to their non-deuterated counterparts. This can lead to improved pharmacokinetic properties, such as increased half-life and reduced toxicity. Recent studies have shown that deuterated analogs of certain drugs can have enhanced therapeutic effects while minimizing side effects.

A notable example of the application of deuterated compounds in pharmaceuticals is the development of deutetrabenazine (Austedo), which is used to treat Huntington's disease. The deuterium atoms in deutetrabenazine contribute to its improved metabolic stability and reduced formation of toxic metabolites. Similarly, 2,6-Dimethylaniline-d9 could potentially serve as a model compound for developing new drugs with improved pharmacological properties.

In addition to its applications in pharmaceuticals, 2,6-Dimethylaniline-d9 is also used in materials science for the synthesis of advanced polymers and functional materials. The unique properties of deuterated compounds make them suitable for use in various polymerization reactions, where they can influence the mechanical properties and thermal stability of the resulting materials.

The synthesis of 2,6-Dimethylaniline-d9 typically involves the deuteration of 2,6-dimethylaniline using deuterium gas or deuterated solvents under controlled conditions. This process requires careful optimization to ensure high yields and purity levels. Recent advancements in deuteration techniques have made it possible to produce high-quality deuterated compounds with greater efficiency and cost-effectiveness.

In conclusion, 2,6-Dimethylaniline-d9 (CAS No. 1021325-45-0) is a versatile compound with a wide range of applications in analytical chemistry, pharmaceutical research, and materials science. Its unique properties make it an invaluable tool for researchers seeking to improve the accuracy and reliability of their analyses or develop new drugs with enhanced therapeutic profiles. As research continues to advance, it is likely that new applications for this compound will be discovered, further expanding its utility in various scientific fields.

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