Cas no 10203-06-2 (4,7-Dichlorobenzo[c]isoxazole)

4,7-Dichlorobenzo[c]isoxazole is a halogenated heterocyclic compound featuring a fused isoxazole and benzene ring system with chlorine substituents at the 4 and 7 positions. This structure imparts notable reactivity, making it a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals. The dichloro substitution enhances its electrophilic character, facilitating selective functionalization. Its rigid aromatic framework contributes to stability while allowing for precise modifications in target molecules. The compound is commonly utilized in cross-coupling reactions and as a precursor for bioactive scaffolds. Proper handling is advised due to potential reactivity hazards.
4,7-Dichlorobenzo[c]isoxazole structure
4,7-Dichlorobenzo[c]isoxazole structure
Product Name:4,7-Dichlorobenzo[c]isoxazole
CAS No:10203-06-2
MF:C7H3Cl2NO
MW:188.010819673538
CID:1095142
PubChem ID:73554718
Update Time:2025-05-27

4,7-Dichlorobenzo[c]isoxazole Chemical and Physical Properties

Names and Identifiers

    • 4,7-Dichlorobenzo[c]isoxazole
    • 4,7-dichloro-benzo[c]isoxazole
    • 10203-06-2
    • 4,7-DICHLORO-2,1-BENZOXAZOLE
    • Inchi: 1S/C7H3Cl2NO/c8-5-1-2-6(9)7-4(5)3-11-10-7/h1-3H
    • InChI Key: XCDPTPFKYZWVEB-UHFFFAOYSA-N
    • SMILES: ClC1=CC=C(C2C1=CON=2)Cl

Computed Properties

  • Exact Mass: 186.9591691g/mol
  • Monoisotopic Mass: 186.9591691g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 155
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3
  • Topological Polar Surface Area: 26?2

4,7-Dichlorobenzo[c]isoxazole Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
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10203-06-2 95%
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Additional information on 4,7-Dichlorobenzo[c]isoxazole

4,7-Dichlorobenzo[c]isoxazole (CAS No. 10203-06-2): Properties, Applications, and Market Insights

4,7-Dichlorobenzo[c]isoxazole (CAS No. 10203-06-2) is a specialized heterocyclic compound that has garnered significant attention in pharmaceutical and agrochemical research. This chlorinated isoxazole derivative exhibits unique structural features, making it a valuable intermediate in synthetic chemistry. With the increasing demand for novel bioactive molecules, understanding the properties and applications of 4,7-dichlorobenzo[c]isoxazole is crucial for researchers and industry professionals alike.

The molecular structure of 4,7-Dichlorobenzo[c]isoxazole consists of a fused benzene and isoxazole ring system, with chlorine atoms at the 4 and 7 positions. This arrangement contributes to its electron-deficient character, enhancing its reactivity in various chemical transformations. Recent studies highlight its role as a key building block in the synthesis of heterocyclic compounds, particularly those with potential biological activity. The compound's thermal stability and solubility profile make it suitable for diverse reaction conditions.

In pharmaceutical applications, 4,7-Dichlorobenzo[c]isoxazole serves as a precursor for developing small molecule therapeutics. Its structural motif appears in compounds targeting enzyme inhibition and receptor modulation, areas of high interest in drug discovery. The agrochemical industry utilizes this compound in developing crop protection agents, where its chlorinated isoxazole core contributes to pesticidal activity. These applications align with current market trends favoring eco-friendly agrochemicals and targeted drug therapies.

The synthesis of 4,7-Dichlorobenzo[c]isoxazole typically involves cyclization reactions of appropriately substituted precursors. Modern synthetic approaches emphasize atom economy and green chemistry principles, reflecting the growing emphasis on sustainable chemical production. Analytical characterization of this compound employs advanced techniques such as NMR spectroscopy and mass spectrometry, ensuring high purity standards for research and industrial applications.

Market analysis indicates steady growth in demand for 4,7-Dichlorobenzo[c]isoxazole, driven by expanding research in medicinal chemistry and crop science. The compound's versatility as a chemical intermediate positions it favorably in specialty chemicals markets. Current research explores its potential in material science applications, particularly in developing functional polymers with specific electronic properties.

Safety considerations for handling 4,7-Dichlorobenzo[c]isoxazole follow standard laboratory protocols for organic compounds. Proper personal protective equipment and ventilation systems are recommended when working with this material. The compound's physicochemical properties and handling guidelines are well-documented in safety data sheets, facilitating its safe use in various applications.

Future prospects for 4,7-Dichlorobenzo[c]isoxazole appear promising, with ongoing research exploring its incorporation into new chemical entities. The compound's structural versatility and reactivity profile continue to attract interest from academic and industrial researchers. As synthetic methodologies advance and application areas expand, 4,7-Dichlorobenzo[c]isoxazole is poised to maintain its relevance in specialty chemical markets and applied research initiatives.

For researchers seeking high-purity 4,7-Dichlorobenzo[c]isoxazole, several specialty chemical suppliers offer the compound in various quantities. Quality parameters typically include ≥98% purity by HPLC analysis, with comprehensive analytical documentation provided. The compound's storage stability under recommended conditions ensures consistent performance in synthetic applications.

In conclusion, 4,7-Dichlorobenzo[c]isoxazole (CAS No. 10203-06-2) represents an important heterocyclic building block with diverse applications across multiple industries. Its unique chemical properties and synthetic utility make it a valuable tool for researchers developing novel compounds with potential biological or material applications. As chemical research continues to evolve, this chlorinated isoxazole derivative will likely find new applications in emerging scientific and technological fields.

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