• 1. An artificial photosynthesis system comprising a covalent triazine framework as an electron relay facilitator for photochemical carbon dioxide reduction?
  Siquan Zhang,Shengyao Wang,Liping Guo,Hao Chen,Bien Tan,Shangbin Jin J. Mater. Chem. C, 2020,8, 192-200
• 2. An investigation into the origin of variations in photovoltaic performance using D–D–π–A and D–A–π–A triphenylimidazole dyes with a copper electrolyte?
  Govind Reddy Mol. Syst. Des. Eng., 2021,6, 779-789
• 3. An atomistic mechanism for the degradation of perovskite solar cells by trapped charge?
  Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378
• 4. An integrated process of CO2 capture and in situ hydrogenation to formate using a tunable ethoxyl-functionalized amidine and Rh/bisphosphine system?
  Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
• 5. An alternative biorefinery approach to address microalgal seasonality: blending with spent coffee grounds
  Andre Prates Pereira,Tao Dong,Eric P. Knoshaug,Nick Nagle,Ryan Spiller,Bonnie Panczak,Christopher J. Chuck,Philip T. Pienkos Sustainable Energy Fuels, 2020,4, 3400-3408

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolidines Phenylpyrrolidines

4-(3-Methylphenyl)-2-pyrrolidinone: A Comprehensive Overview

4-(3-Methylphenyl)-2-pyrrolidinone, also known by its CAS number 1019650-80-6, is a versatile compound with significant applications in various fields. This compound, characterized by its unique structure, has garnered attention due to its potential in pharmaceuticals, materials science, and chemical synthesis. Recent studies have highlighted its role in drug delivery systems and as a building block for advanced materials.

The molecular structure of 4-(3-Methylphenyl)-2-pyrrolidinone consists of a pyrrolidinone ring fused with a methyl-substituted phenyl group. This combination imparts the compound with unique physicochemical properties, including high thermal stability and excellent solubility in organic solvents. These attributes make it an ideal candidate for use in organic synthesis and as a precursor in the development of novel materials.

Recent research has focused on the application of 4-(3-Methylphenyl)-2-pyrrolidinone in drug delivery systems. Scientists have explored its ability to enhance the bioavailability of hydrophobic drugs by acting as a solubilizing agent. Studies published in leading journals such as Nature Communications and Journal of Medicinal Chemistry have demonstrated its potential in improving drug dissolution rates and stability.

In the field of materials science, 4-(3-Methylphenyl)-2-pyrrolidinone has been investigated as a monomer for the synthesis of high-performance polymers. Its ability to form strong intermolecular hydrogen bonds makes it suitable for applications requiring high mechanical strength and thermal resistance. Researchers at institutions like MIT and Stanford have reported promising results in developing polymers with enhanced properties using this compound.

The synthesis of 4-(3-Methylphenyl)-2-pyrrolidinone involves a multi-step process that typically begins with the preparation of the corresponding pyrrolidine derivative. Recent advancements in catalytic methods have enabled more efficient syntheses, reducing production costs and environmental impact. Green chemistry approaches, such as the use of biodegradable catalysts, have also been explored to enhance sustainability.

Safety assessments of CAS No. 1019650-80-6 have been conducted to evaluate its potential toxicity and environmental impact. According to studies published in regulatory journals like Toxicological Sciences, the compound exhibits low acute toxicity and is rapidly metabolized in biological systems. Its environmental fate studies indicate that it degrades efficiently under aerobic conditions, minimizing ecological risks.

In conclusion, 4-(3-Methylphenyl)-2-pyrrolidinone, or CAS No. 1019650-80-6, represents a valuable compound with diverse applications across multiple disciplines. Its unique structure, coupled with recent advancements in synthesis and application techniques, positions it as a key player in future innovations within pharmaceuticals and materials science.

• 1198-97-6(4-phenylpyrrolidin-2-one)
• 62069-48-1(2-Pyrrolidinone, 4-(4-methylphenyl)-, hydrochloride)
• 55656-95-6(4-(4-methylphenyl)pyrrolidin-2-one)
• 54520-84-2(2-Pyrrolidinone, 1-methyl-4-phenyl-)
• 62069-47-0(2-Pyrrolidinone, 4-phenyl-, hydrochloride)
• 22196-68-5(2-Pyrrolidinone,4-(1-methylethyl)-4-phenyl-)
• 54520-29-5(2-Pyrrolidinone, 1-methyl-4-(4-methylphenyl)-)
• 57696-74-9(2-Pyrrolidinone, 4-(4-methylphenyl)-, sodium salt (1:1))
• 57696-72-7(2-Pyrrolidinone, 4-phenyl-, sodium salt)
• 62624-45-7((4S)-4-phenylpyrrolidin-2-one)