Cas no 1018678-50-6 (2-(Difluoromethyl)benzaldehyde)
2-(Difluoromethyl)benzaldehyde is a versatile fluorinated aromatic aldehyde with the molecular formula C8H6F2O. This compound features a difluoromethyl group (–CHF2) attached to the benzaldehyde scaffold, imparting unique electronic and steric properties. The difluoromethyl group enhances the compound's lipophilicity and metabolic stability, making it valuable in pharmaceutical and agrochemical applications. Its aldehyde functionality serves as a reactive handle for further derivatization, enabling the synthesis of diverse heterocycles and intermediates. The electron-withdrawing nature of the difluoromethyl group also influences the reactivity of the aromatic ring, facilitating selective electrophilic substitutions. This compound is particularly useful in medicinal chemistry for designing bioactive molecules, owing to its ability to modulate pharmacokinetic properties. High purity grades are available for research and industrial use.
1018678-50-6 structure
Product Name:2-(Difluoromethyl)benzaldehyde
CAS No:1018678-50-6
MF:C8H6F2O
MW:156.129449367523
MDL:MFCD16875639
CID:1036071
PubChem ID:54772394
Update Time:2025-07-02
2-(Difluoromethyl)benzaldehyde Chemical and Physical Properties
Names and Identifiers
-
- 2-(Difluoromethyl)benzaldehyde
- 1-(2-CHLORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE
- 2-Difluoromethylbenzaldehyde
- difluoromethylphenyl ketone
- 2-Formylbenzal fluoride, alpha,alpha-Difluoro-o-tolualdehyde
- O10520
- Benzaldehyde, 2-(difluoromethyl)-
- SCHEMBL1179123
- DTXSID60716751
- DB-181449
- 1018678-50-6
- MFCD16875639
- AM85447
- SY282540
- BBL103060
- CS-W000088
- AKOS005259036
- EN300-1084868
- Z1255437378
- SB85506
- AS-50012
- STL556869
- DTXCID20667497
-
- MDL： MFCD16875639
- Inchi： 1S/C8H6F2O/c9-8(10)7-4-2-1-3-6(7)5-11/h1-5,8H
- InChI Key： LRGWXJJJRNOVQA-UHFFFAOYSA-N
- SMILES： FC(C1C=CC=CC=1C=O)F
Computed Properties
- Exact Mass: 156.03900
- Monoisotopic Mass: 156.03867113g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 11
- Rotatable Bond Count: 2
- Complexity: 136
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.3
- Topological Polar Surface Area: 17.1?2
Experimental Properties
- PSA: 17.07000
- LogP: 2.43670
2-(Difluoromethyl)benzaldehyde Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM125865-1g |
2-(difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 1g |
$365 | 2021-06-17 | |
| Chemenu | CM125865-5g |
2-(difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 5g |
$795 | 2021-06-17 | |
| Chemenu | CM125865-10g |
2-(difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 10g |
$1122 | 2021-06-17 | |
| Chemenu | CM125865-25g |
2-(difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 25g |
$1870 | 2021-06-17 | |
| Alichem | A019142716-5g |
2-(Difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 5g |
$1207.34 | 2023-09-04 | |
| Alichem | A019142716-10g |
2-(Difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 10g |
$1656.24 | 2023-09-04 | |
| Alichem | A019142716-25g |
2-(Difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 25g |
$2680.00 | 2023-09-04 | |
| Apollo Scientific | PC48438-250mg |
2-(Difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 250mg |
￡55.00 | 2025-02-21 | |
| Apollo Scientific | PC48438-1g |
2-(Difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 1g |
￡130.00 | 2025-02-21 | |
| Apollo Scientific | PC48438-5g |
2-(Difluoromethyl)benzaldehyde |
1018678-50-6 | 95% | 5g |
￡580.00 | 2025-02-21 |
2-(Difluoromethyl)benzaldehyde Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:1018678-50-6)2-(Difluoromethyl)benzaldehyde
Order Number:A897024
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 11:57
Price ($):490.0
Email:[email protected]
2-(Difluoromethyl)benzaldehyde Related Literature
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M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948
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Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
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3. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615
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Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
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Recommended suppliers
Amadis Chemical Company Limited
(CAS:1018678-50-6)2-(Difluoromethyl)benzaldehyde
Purity:99%
Quantity:5g
Price ($):490.0