Cas no 1016538-84-3 (Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate)
Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate is a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and fine chemicals. Its key advantages include a stable tert-butoxycarbonyl (Boc) protecting group, which facilitates selective reactions at other functional sites while maintaining structural integrity under mild conditions. The 3-oxo and 4-propyl substituents enhance its reactivity in cyclization and alkylation reactions, making it valuable for constructing complex heterocyclic frameworks. The compound's well-defined crystalline structure ensures high purity and reproducibility in synthetic applications. Its compatibility with a range of solvents and reagents further underscores its utility in multi-step synthesis, particularly in medicinal chemistry for the development of bioactive molecules.
1016538-84-3 structure
Product Name:Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate
CAS No:1016538-84-3
MF:C12H22N2O3
MW:242.314683437347
MDL:MFCD24466483
CID:2119266
Update Time:2025-06-20
Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate
- tert-butyl 4-propyl-3-oxopiperazine-1-carboxylate
- 1-Piperazinecarboxylic acid, 3-oxo-4-propyl-, 1,1-dimethylethyl ester
- FCH1659570
- T5559
- Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate
-
- MDL： MFCD24466483
- Inchi： 1S/C12H22N2O3/c1-5-6-13-7-8-14(9-10(13)15)11(16)17-12(2,3)4/h5-9H2,1-4H3
- InChI Key： HHYIKSGSIARWAE-UHFFFAOYSA-N
- SMILES： O(C(N1CC(N(CCC)CC1)=O)=O)C(C)(C)C
Computed Properties
- Exact Mass: 242.163
- Monoisotopic Mass: 242.163
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 17
- Rotatable Bond Count: 4
- Complexity: 297
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 49.8
Experimental Properties
- Density: 1.1±0.1 g/cm3
- Boiling Point: 362.2±35.0 °C at 760 mmHg
- Flash Point: 172.9±25.9 °C
- PSA: 49.85000
- LogP: 1.35150
- Vapor Pressure: 0.0±0.8 mmHg at 25°C
Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| abcr | AB416376-500 mg |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | 500MG |
€313.80 | 2023-02-03 | ||
| abcr | AB416376-1 g |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | 1g |
€406.00 | 2023-04-24 | ||
| TRC | T280875-100mg |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | 100mg |
$ 185.00 | 2022-06-02 | ||
| TRC | T280875-250mg |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | 250mg |
$ 380.00 | 2022-06-02 | ||
| TRC | T280875-500mg |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | 500mg |
$ 600.00 | 2022-06-02 | ||
| abcr | AB416376-500mg |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate; . |
1016538-84-3 | 500mg |
€333.00 | 2025-02-15 | ||
| abcr | AB416376-1g |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate; . |
1016538-84-3 | 1g |
€397.00 | 2025-02-15 | ||
| Ambeed | A539913-1g |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | 97% | 1g |
$356.0 | 2024-04-26 | |
| A2B Chem LLC | AI05299-500mg |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | >95% | 500mg |
$523.00 | 2024-04-20 | |
| A2B Chem LLC | AI05299-1g |
tert-Butyl 3-oxo-4-propylpiperazine-1-carboxylate |
1016538-84-3 | >95% | 1g |
$578.00 | 2024-04-20 |
Tert-butyl 3-oxo-4-propylpiperazine-1-carboxylate Related Literature
-
Bruce Parkinson Energy Environ. Sci., 2010,3, 509-511
-
Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
-
Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
-
Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
-
Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
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