Cas no 1015242-08-6 (2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine)
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine is a boronic ester-functionalized pyrimidine derivative with significant utility in cross-coupling reactions, particularly Suzuki-Miyaura couplings. The presence of the 4,4,5,5-tetramethyl-1,3,2-dioxaborolane group enhances stability and solubility in organic solvents, facilitating handling and storage. The dihydropyridinyl moiety contributes to its reactivity profile, making it a versatile intermediate in pharmaceutical and agrochemical synthesis. Its structural features enable selective functionalization, supporting the development of complex heterocyclic frameworks. This compound is particularly valuable in medicinal chemistry for constructing bioactive molecules due to its compatibility with diverse reaction conditions and high functional group tolerance.
1015242-08-6 structure
Product Name:2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
CAS No:1015242-08-6
MF:C15H24BN3O2
MW:289.180963516235
MDL:MFCD07368250
CID:827676
PubChem ID:16414212
Update Time:2025-05-26
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine Chemical and Physical Properties
Names and Identifiers
-
- 2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
- 2-(Piperiden-1-yl)pyrimidine-5-boronic acid, pinacol ester
- 2-piperidin-1-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
- Pyrimidine,2-(1-piperidinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- 2-(1-piperidinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
- 2-(piperidin-1-yl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyrimidine
- 2-(Piperidin-1-yl)pyrimidine-5-boronic acid pinacol ester
- 2-(Piperidin-1-yl)pyrimidine-pound inverted question mark5-boronic pound inverted question markacid pound inverted question markpinacol pound inverted question markester
- 2-PiperidinopyriMidine-5-boronic acid pinacol ester
- 11 2-(Piperidin-1-yl)pyrimidine- 5-boronic acid pinacol ester
- 2-Piperidin-1-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin
- MFCD07368250
- 2-(Piperidin-1-yl)pyrimidine- 5-boronic acid pinacol ester
- D71432
- AKOS015946627
- AB31998
- DTXSID90585957
- BS-19095
- SCHEMBL1841675
- PHVGYFSOPFMYPH-UHFFFAOYSA-N
- [2-(Piperidin-1-yl)pyrimidin-5-yl]boronic acid, pinacol ester
- 2-(PIPERIDIN-1-YL)-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIMIDINE
- J-000419
- 1015242-08-6
- 2-Piperidinopyrimidine-5-boronic acid, pinacol ester
- CS-0130870
-
- MDL： MFCD07368250
- Inchi： 1S/C15H24BN3O2/c1-14(2)15(3,4)21-16(20-14)12-10-17-13(18-11-12)19-8-6-5-7-9-19/h10-11H,5-9H2,1-4H3
- InChI Key： PHVGYFSOPFMYPH-UHFFFAOYSA-N
- SMILES： C1(N2CCCCC2)=NC=C(B2OC(C)(C)C(C)(C)O2)C=N1
Computed Properties
- Exact Mass: 289.19600
- Monoisotopic Mass: 289.1961572g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 21
- Rotatable Bond Count: 2
- Complexity: 348
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 47.5?2
Experimental Properties
- PSA: 47.48000
- LogP: 1.83110
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine Customs Data
- HS CODE：2934999090
- Customs Data：
China Customs Code:
2934999090Overview:
2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029183158-10g |
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine |
1015242-08-6 | 95% | 10g |
$592.80 | 2023-09-04 | |
| TRC | D455553-50mg |
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine |
1015242-08-6 | 50mg |
$ 50.00 | 2022-06-05 | ||
| TRC | D455553-100mg |
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine |
1015242-08-6 | 100mg |
$ 70.00 | 2022-06-05 | ||
| TRC | D455553-500mg |
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine |
1015242-08-6 | 500mg |
$ 250.00 | 2022-06-05 | ||
| Ambeed | A1638901-250mg |
2-(Piperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine |
1015242-08-6 | 98% | 250mg |
$40.0 | 2024-04-26 | |
| Ambeed | A1638901-1g |
2-(Piperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine |
1015242-08-6 | 98% | 1g |
$106.0 | 2024-04-26 | |
| Ambeed | A1638901-5g |
2-(Piperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine |
1015242-08-6 | 98% | 5g |
$394.0 | 2024-04-26 | |
| abcr | AB273935-25g |
2-Piperidinopyrimidine-5-boronic acid pinacol ester, 96%; . |
1015242-08-6 | 96% | 25g |
€1434.90 | 2025-02-16 | |
| A2B Chem LLC | AA05897-250mg |
2-Piperidinopyrimidine-5-boronic acid pinacol ester |
1015242-08-6 | 98% | 250mg |
$26.00 | 2024-01-05 | |
| A2B Chem LLC | AA05897-1g |
2-Piperidinopyrimidine-5-boronic acid pinacol ester |
1015242-08-6 | 98% | 1g |
$78.00 | 2024-04-20 |
2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine Related Literature
-
Huiying Xu,Lu Zheng,Yu Zhou,Bang-Ce Ye Analyst, 2021,146, 5542-5549
-
Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
-
Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
-
Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
1015242-08-6 (2-(3,4-Dihydropyridin-1(2H)-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine) Related Products
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