Cas no 10139-05-6 (N-Amino-D-proline)
N-Amino-D-proline Chemical and Physical Properties
Names and Identifiers
-
- D-Proline, 1-amino-(9CI)
- N-Amino-D-proline
- N-AMINO-D-PROLINE,LIGHT YELLOW CRYSTALS
- d-AMinoglutethiMide L-tartrate
- d-aminoglutethimide tartrate
- D-aminopyrrolidine-2-carboxylic acid
- 1-aminoproline
- 1-Amino-D-proline
- Proline, 1-amino-, D-
- (2R)-1-Amino-2-pyrrolidinecarboxylic acid
- D-PROLINE, 1-AMINO-
- (R)-1-Aminopyrrolidine-2-carboxylic acid
- D-N-aminoproline
- Q27265589
- 10139-05-6
- (2R)-1-aminopyrrolidine-2-carboxylic acid
- 1-amino d-proline
- CS-0259367
- N-Amino-D-proline; LC-tDDA; CE10
- 6VJL5P9K5X
- EN300-7308454
- Z1205495541
- MFCD00269900
- SCHEMBL1633550
- N-Aminoproline, D-
- J-000379
- AKOS006239827
- UNII-6VJL5P9K5X
- D-Proline, 1-amino- (9CI)
-
- Inchi： 1S/C5H10N2O2/c6-7-3-1-2-4(7)5(8)9/h4H,1-3,6H2,(H,8,9)/t4-/m1/s1
- InChI Key： OUCUOMVLTQBZCY-SCSAIBSYSA-N
- SMILES： OC([C@H]1CCCN1N)=O
Computed Properties
- Exact Mass: 130.07400
- Monoisotopic Mass: 130.074228
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 9
- Rotatable Bond Count: 1
- Complexity: 126
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 66.6
- XLogP3: -2.1
Experimental Properties
- Density: 1.3±0.1 g/cm3
- Melting Point: 155-156°C
- Boiling Point: 277.0±33.0 °C at 760 mmHg
- Flash Point: 121.3±25.4 °C
- Refractive Index: 1.548
- PSA: 66.56000
- LogP: 0.04730
- Vapor Pressure: 0.0±1.2 mmHg at 25°C
N-Amino-D-proline Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
N-Amino-D-proline Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
N-Amino-D-proline Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | A628000-25mg |
N-Amino-D-proline |
10139-05-6 | 25mg |
$ 161.00 | 2023-04-19 | ||
| TRC | A628000-50mg |
N-Amino-D-proline |
10139-05-6 | 50mg |
$ 228.00 | 2023-04-19 | ||
| TRC | A628000-100mg |
N-Amino-D-proline |
10139-05-6 | 100mg |
$ 397.00 | 2023-04-19 | ||
| TRC | A628000-250mg |
N-Amino-D-proline |
10139-05-6 | 250mg |
$ 907.00 | 2023-04-19 | ||
| TRC | A628000-500mg |
N-Amino-D-proline |
10139-05-6 | 500mg |
$ 1590.00 | 2023-04-19 | ||
| A2B Chem LLC | AA05477-50mg |
D-Proline, 1-amino-(9CI) |
10139-05-6 | 95% | 50mg |
$314.00 | 2024-04-20 | |
| A2B Chem LLC | AA05477-100mg |
D-Proline, 1-amino-(9CI) |
10139-05-6 | 95% | 100mg |
$450.00 | 2024-04-20 | |
| A2B Chem LLC | AA05477-250mg |
D-Proline, 1-amino-(9CI) |
10139-05-6 | 95% | 250mg |
$627.00 | 2024-04-20 | |
| A2B Chem LLC | AA05477-500mg |
D-Proline, 1-amino-(9CI) |
10139-05-6 | 95% | 500mg |
$967.00 | 2024-04-20 | |
| A2B Chem LLC | AA05477-1g |
D-Proline, 1-amino-(9CI) |
10139-05-6 | 95% | 1g |
$1230.00 | 2024-04-20 |
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Additional information on N-Amino-D-proline
Introduction to N-Amino-D-proline (CAS No. 10139-05-6)
N-Amino-D-proline, a compound with the chemical name CAS No. 10139-05-6, is a significant molecule in the field of chemical biology and pharmaceutical research. This enantiomer of proline has garnered considerable attention due to its unique structural and functional properties, which make it a valuable building block in the synthesis of various bioactive molecules.
The compound N-Amino-D-proline belongs to the class of amino acids, specifically the D-form, which is less common in natural proteins compared to its L-form counterpart. However, its non-proteinogenic nature and distinct stereochemistry have opened up new avenues in drug design and peptide synthesis. The presence of an amino group at the nitrogen atom and a proline ring structure imparts unique reactivity and conformational flexibility, making it a versatile intermediate in organic synthesis.
In recent years, the study of D-amino acids, including N-Amino-D-proline, has seen significant advancements due to their potential applications in peptidomimetics and enzyme inhibition. Researchers have been exploring the use of D-amino acids to develop novel therapeutic agents that can overcome the limitations associated with traditional L-amino acid-based drugs. For instance, D-amino acid-containing peptides have shown promise in inhibiting proteases and other enzymes involved in various pathological processes.
One of the most intriguing aspects of N-Amino-D-proline is its role in the development of cyclic peptides and peptidomimetics. These cyclic structures often exhibit enhanced stability and bioavailability compared to their linear counterparts. The rigid proline ring within these molecules can provide structural constraints that improve binding affinity and specificity to target proteins. This has led to the exploration of N-Amino-D-proline-based compounds in the design of antiviral, anticancer, and anti-inflammatory agents.
Recent studies have also highlighted the importance of N-Amino-D-proline in modulating enzyme activity. For example, certain proteases preferentially cleave D-amino acid residues, making them potential targets for therapeutic intervention. By incorporating N-Amino-D-proline into peptide sequences, researchers can design molecules that selectively inhibit these enzymes without affecting other biological processes. This approach has been particularly useful in developing treatments for infectious diseases caused by protease-dependent pathogens.
The synthetic chemistry of N-Amino-D-proline has also seen significant progress. The development of efficient synthetic routes has enabled researchers to produce this compound in larger quantities, facilitating its use in various research applications. Additionally, advances in solid-phase peptide synthesis have made it possible to incorporate N-Amino-D-proline into complex peptide sequences with high precision. These advancements have not only improved the accessibility of this compound but also expanded its potential applications in drug discovery and molecular biology.
In conclusion, N-Amino-D-proline (CAS No. 10139-05-6) is a multifaceted compound with broad applications in chemical biology and pharmaceutical research. Its unique structural and functional properties make it a valuable tool for developing novel therapeutic agents, peptidomimetics, and enzyme inhibitors. As research continues to uncover new applications for this compound, its significance in drug discovery and molecular biology is expected to grow further.
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