• 1. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
• 2. Estimation of activation energy for electroporation and pore growth rate in liquid crystalline and gel phases of lipid bilayers using molecular dynamics simulations?
  Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
• 3. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 4. Exciton manipulation in rippled transition metal dichalcogenides?
  Chen Long,Ying Dai,Jianwei Li,Hao Jin Nanoscale, 2020,12, 21124-21130
• 5. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylpropanes

Introduction to (2,6-Difluoro-4-propylphenyl)boronic Acid (CAS No. 1010110-74-3)

(2,6-Difluoro-4-propylphenyl)boronic acid, also known by its CAS registry number CAS No. 1010110-74-3, is a highly specialized organic compound that has garnered significant attention in the fields of organic synthesis, materials science, and drug discovery. This compound belongs to the class of boronic acids, which are widely recognized for their versatility in forming carbon-carbon bonds through the Suzuki-Miyaura coupling reaction. The structure of this compound features a phenyl ring substituted with two fluorine atoms at the 2 and 6 positions and a propyl group at the 4 position, making it a valuable building block in modern chemical research.

The synthesis of (2,6-Difluoro-4-propylphenyl)boronic acid typically involves multi-step processes that combine aromatic substitution reactions with boron-based chemistry. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing production costs and enhancing purity levels. The compound's unique electronic properties, derived from the electron-withdrawing fluorine atoms and the electron-donating propyl group, make it an ideal candidate for various applications.

In terms of applications, (2,6-Difluoro-4-propylphenyl)boronic acid has been extensively used in the construction of biaryl compounds, which are critical intermediates in pharmaceutical development. For instance, researchers have employed this compound to synthesize potential drug candidates targeting various diseases, including cancer and neurodegenerative disorders. The fluorine substituents not only enhance the stability of the molecule but also improve its bioavailability when incorporated into drug designs.

Recent studies have also explored the use of (2,6-Difluoro-4-propylphenyl)boronic acid in materials science, particularly in the development of advanced polymers and organic electronics. Its ability to form stable cross-linked structures has made it a promising component in high-performance materials such as light-emitting diodes (LEDs) and flexible electronics. Additionally, its role in click chemistry has opened new avenues for rapid assembly of complex molecules.

The safety profile of (2,6-Difluoro-4-propylphenyl)boronic acid is generally favorable under controlled conditions; however, proper handling procedures should be followed to ensure workplace safety. Storage recommendations include keeping the compound in a cool, dry place away from direct sunlight to maintain its stability over time.

Looking ahead, ongoing research is focused on optimizing the synthesis pathways for (2,6-Difluoro-4-propylphenyl)boronic acid to further enhance its scalability and reduce environmental impact. Collaborative efforts between academic institutions and industry partners are expected to yield innovative applications that leverage this compound's unique properties.

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