• 1. Application of novel solid phase extraction-NMR protocols for metabolic profiling of human urine
  Daniel McGill,Elena Chekmeneva,John C. Lindon,Zoltan Takats,Jeremy K. Nicholson Faraday Discuss. 2019 218 395
• 2. Elucidating time-dependent changes in the urinary metabolome of renal transplant patients by a combined 1H NMR and GC-MS approach
  Muhrez Kienana,Nadal-Desbarats Lydie,Halimi Jean-Michel,Dieme Binta,Büchler Matthias,Emond Patrick,Blasco Hélène,Le Guellec Chantal Mol. BioSyst. 2015 11 2493
• 3. Elucidating time-dependent changes in the urinary metabolome of renal transplant patients by a combined 1H NMR and GC-MS approach
  Muhrez Kienana,Nadal-Desbarats Lydie,Halimi Jean-Michel,Dieme Binta,Büchler Matthias,Emond Patrick,Blasco Hélène,Le Guellec Chantal Mol. BioSyst. 2015 11 2493
• 4. Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
  Warwick B. Dunn,David I. Broadhurst,Helen J. Atherton,Royston Goodacre,Julian L. Griffin Chem. Soc. Rev. 2011 40 387
• 5. Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes
  Susan C. Connor,Michael K. Hansen,Adam Corner,Randall F. Smith,Terence E. Ryan Mol. BioSyst. 2010 6 909

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxamides
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxamides

Comprehensive Overview of N-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS No. 1007-18-7): Properties, Applications, and Research Insights

N-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide, identified by its CAS number 1007-18-7, is a specialized organic compound with a unique molecular structure. This compound belongs to the pyridine derivative family, which is widely studied for its potential applications in pharmaceuticals, agrochemicals, and material science. The N-Methyl and carboxamide functional groups in its structure contribute to its reactivity and versatility, making it a subject of interest for researchers and industry professionals alike.

In recent years, the demand for pyridine-based compounds has surged due to their role in drug discovery and development. N-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide is no exception, as its structural features align with the growing focus on heterocyclic chemistry and small molecule therapeutics. Researchers are particularly intrigued by its potential as a building block for bioactive molecules, which could address unmet medical needs in areas such as oncology, neurology, and infectious diseases.

The synthesis of CAS 1007-18-7 involves multi-step organic reactions, often starting from readily available pyridine precursors. Key steps may include N-methylation, oxidation, and amide formation, with careful optimization required to achieve high yields and purity. Analytical techniques such as NMR spectroscopy, mass spectrometry, and HPLC are routinely employed to characterize this compound, ensuring its suitability for further applications.

One of the most discussed topics in the context of N-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide is its potential role in green chemistry and sustainable synthesis. With increasing environmental awareness, researchers are exploring eco-friendly routes to produce such compounds, minimizing waste and energy consumption. This aligns with the broader trend of sustainable pharmaceutical manufacturing, a hot topic in both academic and industrial circles.

From a commercial perspective, CAS 1007-18-7 is often sourced by pharmaceutical and biotechnology companies for high-throughput screening and medicinal chemistry programs. Its molecular scaffold is considered valuable for designing kinase inhibitors and enzyme modulators, which are pivotal in modern drug development. Additionally, the compound's stability and solubility profile make it a practical choice for in vitro and in vivo studies.

Beyond pharmaceuticals, N-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide has garnered attention in material science. Its conjugated system and functional groups offer opportunities for developing organic electronic materials, such as semiconductors and light-emitting diodes (LEDs). This interdisciplinary appeal underscores the compound's versatility and potential for innovation across multiple fields.

Safety and handling of CAS 1007-18-7 are also critical considerations. While not classified as hazardous under standard regulations, proper laboratory practices, including the use of personal protective equipment (PPE) and ventilation systems, are recommended. Regulatory compliance, particularly in regions with stringent chemical oversight, is essential for its procurement and use.

In summary, N-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS No. 1007-18-7) represents a fascinating intersection of chemistry, biology, and materials science. Its structural uniqueness and functional diversity position it as a valuable asset in research and industrial applications. As scientific advancements continue, this compound is likely to play an increasingly prominent role in addressing global challenges in health and technology.

• 701-44-0(Nudifloramide)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)