Cas no 1004-74-6 (pyrimidine-2,4,5,6-tetramine)

Pyrimidine-2,4,5,6-tetramine is a heterocyclic organic compound featuring a pyrimidine core substituted with four amine groups at positions 2, 4, 5, and 6. This structure imparts high reactivity and versatility, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. Its multiple amine groups enable diverse functionalization, facilitating the development of biologically active molecules, including nucleoside analogs and enzyme inhibitors. The compound’s stability under controlled conditions and compatibility with various coupling reactions enhance its utility in medicinal chemistry research. Pyrimidine-2,4,5,6-tetramine is particularly useful in constructing complex molecular frameworks, offering synthetic efficiency for targeted drug discovery and development.
pyrimidine-2,4,5,6-tetramine structure
pyrimidine-2,4,5,6-tetramine structure
Product Name:pyrimidine-2,4,5,6-tetramine
CAS No:1004-74-6
MF:C4H8N6
MW:140.146518707275
MDL:MFCD00152825
CID:40514
PubChem ID:70487
Update Time:2025-11-02

pyrimidine-2,4,5,6-tetramine Chemical and Physical Properties

Names and Identifiers

    • 2,4,5,6-Tetraaminopyrimidine
    • 2,4,5,6-Pyrimidinetetraamine
    • 2,4,5,6-Pyrimidinetetramine
    • 2,4,5,6-TETRAAMINOPYRIMIDINE SULFATE SALT
    • FMOC-VAL-OSU
    • 2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL(PIPERIDIN-4-YL)METHANONE
    • 2,4,5,6-tetraaminopyridine
    • 2,4,5,6-tetraamino-pyrimidine
    • 2,4,5,6-Tetraaminopyrimidine sulphate monohydrate
    • 2,4,5,6-tetraminopyrimidine
    • EINECS 213-724-9
    • Pyrimidine,2,4,5,6-tetraamino
    • Pyrimidine-2,4,5,6-Tetraamine
    • Pyrimidinetetramine
    • tetraaminopyrimidine
    • Pyrini-dinetetramine
    • Pyrimidinetetraamine
    • 2,4,5,6-tetraamino-pyrimidin
    • 2,4,5,6-Tetraaminopyrimidiine
    • 2,4,5,6-Tetraaminopyrimidine ,97%
    • 2,4,5,6-tetraaminopyrimidinesulphatemonohydrate
    • pyrimidine-2,4,5,6-tetramine
    • CHEMBL2151966
    • AS-59260
    • 5-25-12-00377 (Beilstein Handbook Reference)
    • (2,4,6-triamino-pyrimidin-5-yl)-amine
    • E80414
    • UNII-24FC717FE5
    • SCHEMBL33841
    • PYRIMIDINE, TETRAAMINO-
    • DTXSID9043807
    • AKOS005665274
    • SB55973
    • HY-D1061
    • CS-0104923
    • AC-26744
    • EN300-143670
    • BRN 0144442
    • MFCD00152825
    • tetra-aminopyrimidine
    • Pyrimidine, 2,4,5,6-tetraamino-
    • Q15726087
    • FT-0633232
    • 2,4,5,6-Pyrimidinetetramine #
    • 24FC717FE5
    • 1004-74-6
    • DTXCID7023807
    • STK935566
    • BBL028285
    • MDL: MFCD00152825
    • Inchi: 1S/C4H8N6/c5-1-2(6)9-4(8)10-3(1)7/h5H2,(H6,6,7,8,9,10)
    • InChI Key: PZRKPUQWIFJRKZ-UHFFFAOYSA-N
    • SMILES: N1C(N)=NC(=C(C=1N)N)N

Computed Properties

  • Exact Mass: 140.08100
  • Monoisotopic Mass: 140.081
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 6
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 0
  • Complexity: 104
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 130A^2
  • Surface Charge: 0
  • Tautomer Count: 15
  • XLogP3: -1.5

Experimental Properties

  • Color/Form: Crystallize (water)
  • Density: 1.648
  • Boiling Point: 563.918°C at 760 mmHg
  • Flash Point: 329.4°C
  • PSA: 129.86000
  • LogP: 1.13020

pyrimidine-2,4,5,6-tetramine Security Information

  • Hazard Category Code: 20/22
  • Safety Instruction: 36/37
  • Storage Condition:Sealed in dry,2-8°C(BD2369)

pyrimidine-2,4,5,6-tetramine Customs Data

  • HS CODE:2933599090
  • Customs Data:

    China Customs Code:

    2933599090

    Overview:

    2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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pyrimidine-2,4,5,6-tetramine Suppliers

Amadis Chemical Company Limited
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(CAS:1004-74-6)pyrimidine-2,4,5,6-tetramine
Order Number:A800214
Stock Status:in Stock
Quantity:25g/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:35
Price ($):812.0/233.0

Additional information on pyrimidine-2,4,5,6-tetramine

Exploring Pyrimidine-2,4,5,6-tetramine (CAS No. 1004-74-6): Properties, Applications, and Future Prospects

Pyrimidine-2,4,5,6-tetramine (CAS No. 1004-74-6) is a specialized organic compound that has garnered significant attention in recent years due to its unique chemical structure and versatile applications. As a derivative of pyrimidine, this compound features four amino groups attached to the pyrimidine ring, making it a valuable building block in various chemical syntheses. Researchers and industries are increasingly interested in pyrimidine-2,4,5,6-tetramine for its potential in pharmaceuticals, agrochemicals, and material science.

The molecular formula of pyrimidine-2,4,5,6-tetramine is C4H8N6, and it exhibits a high nitrogen content, which contributes to its reactivity and utility in diverse chemical reactions. The compound's CAS number 1004-74-6 serves as a unique identifier in chemical databases, ensuring accurate referencing in scientific literature and commercial transactions. With the growing demand for nitrogen-rich compounds in sustainable chemistry, pyrimidine-2,4,5,6-tetramine is emerging as a key player in green synthesis and catalytic processes.

One of the most notable applications of pyrimidine-2,4,5,6-tetramine is in the development of novel pharmaceutical agents. The compound's ability to form hydrogen bonds and interact with biological targets makes it a promising candidate for drug design. Recent studies have explored its potential as a precursor for antiviral and anticancer agents, aligning with the global focus on combating infectious diseases and cancer. The pyrimidine scaffold is a common motif in many FDA-approved drugs, and the tetramine variant offers additional functionalization opportunities.

In the field of materials science, pyrimidine-2,4,5,6-tetramine has shown promise in the synthesis of advanced polymers and coordination complexes. Its multiple amino groups enable the formation of stable metal-organic frameworks (MOFs), which are highly sought after for gas storage, separation technologies, and catalysis. As industries strive for more efficient and environmentally friendly materials, pyrimidine-based compounds like this one are gaining traction in research and development pipelines.

The agrochemical sector has also recognized the potential of pyrimidine-2,4,5,6-tetramine as a building block for novel pesticides and herbicides. With increasing concerns about food security and sustainable agriculture, researchers are investigating nitrogen-rich compounds that can enhance crop protection while minimizing environmental impact. The tetramine functional groups in this compound offer unique modes of action against pests and pathogens, making it a valuable asset in modern agrochemical design.

From a synthetic chemistry perspective, pyrimidine-2,4,5,6-tetramine presents interesting challenges and opportunities. The compound's high nitrogen content requires careful handling during synthesis and purification, but this same characteristic makes it an excellent precursor for various heterocyclic compounds. Recent advances in flow chemistry and microwave-assisted synthesis have improved the efficiency of producing pyrimidine derivatives, including this tetramine variant, with higher yields and purity.

The market for pyrimidine-2,4,5,6-tetramine is expected to grow steadily in the coming years, driven by increasing demand from pharmaceutical and material science applications. As patent landscapes evolve and new therapeutic areas emerge, this compound is likely to play a significant role in next-generation drug development. Companies specializing in fine chemicals and custom synthesis are expanding their portfolios to include high-purity pyrimidine derivatives to meet this growing demand.

Quality control and analytical characterization of pyrimidine-2,4,5,6-tetramine are crucial aspects of its commercial and research applications. Advanced techniques such as HPLC, NMR spectroscopy, and mass spectrometry are routinely employed to verify the compound's purity and structure. The CAS registry number 1004-74-6 ensures proper identification and tracking of this substance across global chemical inventories and regulatory databases.

Environmental and safety considerations surrounding pyrimidine-2,4,5,6-tetramine are important factors in its handling and use. While the compound itself is not classified as hazardous under current regulations, proper laboratory practices should always be followed when working with any chemical substance. Researchers are increasingly focused on developing greener synthetic routes for nitrogen-containing heterocycles to minimize waste and energy consumption.

Looking to the future, pyrimidine-2,4,5,6-tetramine is poised to contribute to several cutting-edge scientific areas. Its potential applications in energy storage systems, particularly in the development of novel battery materials, are currently being explored. Additionally, the compound's ability to form stable complexes with various metal ions makes it interesting for catalytic applications in renewable energy technologies. As the scientific community continues to investigate multifunctional pyrimidine derivatives, this tetramine variant is likely to feature prominently in innovative solutions across multiple disciplines.

For researchers and industry professionals seeking reliable information about pyrimidine-2,4,5,6-tetramine, it's essential to consult peer-reviewed literature and reputable chemical databases. The compound's CAS number 1004-74-6 serves as a key reference point for accessing accurate data about its properties, synthesis methods, and applications. As interest in specialized heterocyclic compounds grows, this pyrimidine derivative represents an exciting area of chemical research with significant practical implications.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:1004-74-6)pyrimidine-2,4,5,6-tetramine
A800214
Purity:99%/99%
Quantity:25g/5g
Price ($):812.0/233.0
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