• 1. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 2. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?
  Xiaotong Feng,Lei Bian,Jie Ma,Lei Zhou,Xiayan Wang,Guangsheng Guo,Qiaosheng Pu Chem. Commun., 2019,55, 3963-3966
• 3. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 4. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 5. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Alkyl aryl ethers
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ethers Alkyl aryl ethers

Introduction to (2-Ethoxypyrimidin-5-yl)methanamine and Its Significance in Modern Chemical Research

The compound with the CAS number 1003853-94-8 is known as (2-Ethoxypyrimidin-5-yl)methanamine, a molecule that has garnered significant attention in the field of chemical biology and pharmaceutical research. This compound, characterized by its unique structural and functional properties, plays a crucial role in the development of novel therapeutic agents and diagnostic tools. Its molecular structure, featuring an ethoxy group attached to a pyrimidine ring and a methanamine substituent, makes it a versatile intermediate in synthetic chemistry, particularly in the synthesis of more complex molecules.

In recent years, the study of heterocyclic compounds has seen remarkable advancements, with pyrimidine derivatives being extensively explored for their potential biological activities. The pyrimidine core is a fundamental motif in many natural products and pharmaceuticals, including antiviral, anticancer, and antimicrobial agents. The introduction of functional groups such as ethoxy and amine into this framework can significantly alter its pharmacological properties, making it an attractive scaffold for drug discovery.

(2-Ethoxypyrimidin-5-yl)methanamine has been investigated for its role in various biochemical pathways and its potential as a precursor for more complex molecules. Its reactivity allows for further functionalization, enabling researchers to design and synthesize novel compounds with tailored properties. This flexibility has made it a valuable tool in medicinal chemistry, particularly in the development of small-molecule inhibitors targeting specific enzymes or receptors.

One of the most compelling aspects of this compound is its application in the synthesis of kinase inhibitors. Kinases are enzymes that play a critical role in cell signaling pathways and are often implicated in various diseases, including cancer. By designing molecules that specifically inhibit certain kinases, researchers can develop targeted therapies that minimize side effects associated with broader treatments. The pyrimidine ring in (2-Ethoxypyrimidin-5-yl)methanamine provides a suitable platform for such interactions, while the ethoxy and amine groups can be optimized to enhance binding affinity and selectivity.

Recent studies have also explored the use of this compound in the development of antiviral agents. Viruses rely on host cellular machinery for replication, and by targeting specific viral proteins or enzymes, antiviral drugs can effectively inhibit viral replication. The structural features of (2-Ethoxypyrimidin-5-yl)methanamine make it a promising candidate for designing molecules that disrupt viral life cycles. For instance, modifications to the ethoxy group or the amine substituent can alter its ability to interact with viral proteases or polymerases, thereby blocking viral replication.

The compound's significance extends beyond its applications in drug development. It serves as an important intermediate in synthetic chemistry, allowing researchers to construct more complex molecules through various organic reactions. The presence of reactive sites such as the amine group enables nucleophilic substitution reactions, while the pyrimidine ring can participate in condensation reactions to form new heterocyclic structures. This versatility makes it a valuable building block for chemists working on diverse synthetic challenges.

In addition to its synthetic utility, (2-Ethoxypyrimidin-5-yl)methanamine has been studied for its potential role in materials science. Heterocyclic compounds are known for their diverse electronic properties, which make them suitable candidates for applications in organic electronics, such as organic light-emitting diodes (OLEDs) and photovoltaic cells. The electronic structure of this compound can be fine-tuned by introducing additional functional groups or by altering the substitution pattern on the pyrimidine ring. Such modifications can enhance its performance as an electron donor or acceptor, making it useful in developing next-generation electronic devices.

The exploration of this compound also highlights the importance of computational chemistry in modern research. Advanced computational methods allow researchers to predict the properties and reactivities of molecules before they are synthesized experimentally. This approach not only saves time and resources but also enables the design of molecules with specific desired characteristics. By combining experimental data with computational modeling, scientists can gain deeper insights into the structure-activity relationships of (2-Ethoxypyrimidin-5-yl)methanamine and related compounds.

In conclusion, (2-Ethoxypyrimidin-5-yl)methanamine (CAS no: 1003853-94-8) is a multifaceted compound with significant implications in pharmaceutical research, synthetic chemistry, and materials science. Its unique structural features make it a valuable tool for developing novel therapeutic agents, intermediates for complex syntheses, and components for advanced materials. As research continues to uncover new applications and functionalities of this compound, its importance is likely to grow further, contributing to advancements across multiple scientific disciplines.

• 17758-09-7(Pyrimidine,2-ethoxy-5-methyl-)
• 944905-26-4(C-[2-(2,2,2-Trifluoro-ethoxy)-pyriMidin-5-yl]-MethylaMine)
• 2089335-05-5(Bis((2-methoxypyrimidin-5-yl)methyl)amine)
• 2024543-44-8((2-Methoxypyrimidin-5-yl)methanamine hydrochloride)
• 1379251-74-7((2-Ethoxypyrimidin-5-yl)methanol)
• 944899-18-7((2-Methoxypyrimidin-5-yl)methanamine)
• 17758-07-5(2-Methoxy-5-methylpyrimidine)
• 1250928-71-2(2-(pyrimidin-2-yloxy)ethan-1-amine)
• 1856235-46-5([2-(Propan-2-yloxy)pyrimidin-5-yl]methanamine)
• 1158735-09-1((2-methoxypyrimidin-5-yl)methanol)