Cas no 1003043-46-6 ((2,6-Diethoxypyridin-3-yl)boronic Acid)

(2,6-Diethoxypyridin-3-yl)boronic acid is a boronic acid derivative featuring a pyridine core substituted with ethoxy groups at the 2- and 6-positions. This compound is widely utilized as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex biaryl and heteroaryl structures. The electron-donating ethoxy groups enhance the stability and reactivity of the boronic acid moiety, facilitating efficient coupling under mild conditions. Its high purity and consistent performance make it valuable in pharmaceutical and agrochemical research, particularly for constructing pyridine-based scaffolds. The compound's stability under standard handling conditions further ensures reliable use in synthetic applications.
(2,6-Diethoxypyridin-3-yl)boronic Acid structure
1003043-46-6 structure
Product Name:(2,6-Diethoxypyridin-3-yl)boronic Acid
CAS No:1003043-46-6
MF:C9H14BNO4
MW:211.022762775421
MDL:MFCD11617267
CID:827705
Update Time:2025-10-28

(2,6-Diethoxypyridin-3-yl)boronic Acid Chemical and Physical Properties

Names and Identifiers

    • B-(2,6-diethoxy-3-pyridinyl)-Boronic acid
    • (2,6-Diethoxypyridin-3-yl)boronic acid
    • Boronic acid, B-(2,6-diethoxy-3-pyridinyl)-
    • 2,6-DIETHOXYPYRIDINE-3-BORONIC ACID
    • (2,6-Diethoxypyridin-3-yl)boronic Acid
    • MDL: MFCD11617267
    • Inchi: 1S/C9H14BNO4/c1-3-14-8-6-5-7(10(12)13)9(11-8)15-4-2/h5-6,12-13H,3-4H2,1-2H3
    • InChI Key: HTELBRAIBMTDOF-UHFFFAOYSA-N
    • SMILES: O(CC)C1C(B(O)O)=CC=C(N=1)OCC

Computed Properties

  • Exact Mass: 211.10200
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 5

Experimental Properties

  • PSA: 71.81000
  • LogP: -0.44120

(2,6-Diethoxypyridin-3-yl)boronic Acid Pricemore >>

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Additional information on (2,6-Diethoxypyridin-3-yl)boronic Acid

(2,6-Diethoxypyridin-3-yl)boronic Acid: A Comprehensive Overview

The compound (2,6-Diethoxypyridin-3-yl)boronic Acid with CAS number 1003043-46-6 is a significant molecule in the field of organic synthesis and materials science. This compound has garnered attention due to its unique structural properties and potential applications in various scientific domains. In this article, we delve into the structural characteristics, synthesis methods, and recent advancements in its applications.

Structural Insights: The molecule (2,6-Diethoxypyridin-3-yl)boronic Acid consists of a pyridine ring substituted with ethoxy groups at positions 2 and 6, and a boronic acid group at position 3. This arrangement imparts the molecule with both electron-donating and electron-withdrawing functionalities, making it versatile for various chemical reactions. The pyridine ring's aromaticity contributes to its stability, while the boronic acid group facilitates cross-coupling reactions, a cornerstone in modern organic synthesis.

Synthesis Methods: The synthesis of (2,6-Diethoxypyridin-3-yl)boronic Acid typically involves multi-step processes that combine traditional organic chemistry techniques with modern catalytic methods. Recent studies have focused on optimizing these processes to enhance yield and purity. For instance, researchers have explored the use of palladium catalysts in Suzuki-Miyaura couplings to streamline the formation of the boronic acid group.

Applications in Materials Science: One of the most promising applications of (2,6-Diethoxypyridin-3-yl)boronic Acid lies in its use as a building block for advanced materials. Its ability to undergo cross-coupling reactions makes it ideal for constructing complex organic frameworks used in electronics and optoelectronics. Recent research highlights its role in synthesizing novel semiconducting materials with tailored electronic properties.

Biological Applications: Beyond materials science, (2,6-Diethoxypyridin-3-yl)boronic Acid has shown potential in drug discovery efforts. Its structural versatility allows for the creation of bioactive molecules that target specific cellular pathways. For example, studies have demonstrated its utility in synthesizing compounds with anti-inflammatory and anticancer properties.

Environmental Considerations: As with any chemical compound, understanding the environmental impact of (2,6-Diethoxypyridin-3-yl)boronic Acid is crucial. Researchers are investigating its biodegradability and toxicity to ensure sustainable practices in its production and application.

In conclusion, (2,6-Diethoxypyridin-3-yl)boronic Acid (CAS 1003043-46-6) stands as a testament to the ingenuity of modern organic chemistry. Its diverse applications and ongoing research advancements underscore its importance in both academic and industrial settings.

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