Cas no 10029-07-9 ((1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans)

(1r,4r)-4-(Aminomethyl)cyclohexylmethanamine (trans) is a chiral diamine compound featuring a cyclohexane backbone with two primary amine functional groups in the trans configuration. Its rigid cyclohexane structure and well-defined stereochemistry make it a valuable building block in asymmetric synthesis, catalysis, and pharmaceutical intermediates. The trans orientation enhances steric control, improving selectivity in reactions such as Schiff base formation or metal-ligand coordination. This compound is particularly useful in the development of chiral ligands for enantioselective transformations. Its high purity and stability under standard conditions ensure consistent performance in demanding applications. The bifunctional nature of the amine groups allows for versatile derivatization, making it a preferred choice for fine chemical synthesis.
(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans structure
10029-07-9 structure
Product Name:(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans
CAS No:10029-07-9
MF:C8H18N2
MW:142.241921901703
MDL:MFCD20037427
CID:230057
PubChem ID:17354
Update Time:2025-08-05

(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans Chemical and Physical Properties

Names and Identifiers

    • 1,4-Cyclohexanedimethanamine,trans-
    • trans-1,4-Bis(aminomethyl)cyclohexane
    • [4-(aminomethyl)cyclohexyl]methanamine
    • trans-1,4-Cyclohexanedimethanamine
    • 1r-Brom-4t-chlor-cyclohexan
    • 1r-bromo-4t-chloro-cyclohexane
    • bis-1,4-aminomethylcyclohexane
    • Cyclohexane,1-bromo-4-chloro
    • Cyclohexane,1-bromo-4-chloro-,trans
    • trans-1,4-bis(aminomethyl)cyclohexa
    • trans-1,4-Bis-(aminomethyl)-cyclohexan
    • trans-1,4-Bromchlorcyclohexan
    • trans-1,4-cyclohexanebis(methyamine)
    • trans-1,4-cyclohexylenebis(methylamine)
    • trans-1-Brom-4-chlor-cyclohexan
    • trans-Hexahydro-p-xylylenediamine
    • trans-1,4-Di(aminomethyl)cyclohexane
    • 1,4-Bis(aminomethyl)cyclohexane
    • cis-1,4-Bis(aminomethyl)cyclohexane
    • 1,4-Cyclohexanedimethanamine
    • Bamch
    • Cyclohexane-1,4-diyldimethanamine
    • 1,4-Cyclohexanebis(methylamine)
    • Cyclohex-1,4-ylenebis(methylamine)
    • Hexahydro-p-xylylenediamine
    • CYCLOHEXANE, 1,4-BIS(AMINOMETHYL)-
    • 1,4-Di(aminomethyl)cyclohexane
    • OXIKYYJDTWKERT-ZKCHVHJHSA-N
    • OXI
    • (1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans
    • EINECS 219-840-6
    • Cyclohexane-1alpha,4beta-bis(methanamine)
    • BP-13457
    • 10029-07-9
    • SCHEMBL48375
    • NSC-71997
    • MFCD00039463
    • J-016021
    • FT-0606788
    • 1,4-bis-aminomethylcyclohexane
    • 1,4-Cyclohexylenebis(methylamine)
    • FT-0746025
    • cis-1,4-Cyclohexanedimethanamine
    • DTXSID4062511
    • A817882
    • EN300-2994142
    • 1,4-bisaminomethlycyclohexane
    • NSC-71995
    • F14924
    • SB30038
    • NS00019888
    • cis-1,4-Cyclohexanebis(methylamine)
    • 1,4-Cyclohexanedimethylamine, trans-
    • 1,4-Cyclohexanebis(methylamine), cis-
    • 1.4-Cyclohexane-bis(methylamine)
    • cis-1,4-Di(aminomethyl)cyclohexane
    • J-500354
    • 1-[(1R,4R)-4-(AMINOMETHYL)CYCLOHEXYL]METHANAMINE
    • MFCD20037427
    • 1,4-cyclohexane-bis(methylamine)
    • OXIKYYJDTWKERT-OCAPTIKFSA-N
    • B5146
    • SCHEMBL13211924
    • 10029-09-1
    • cis-Hexahydro-p-xylylenediamine
    • NSC71995
    • 1,4-Cyclohexanedimethanamine, cis-
    • T70001
    • 1-[(1S,4S)-4-(AMINOMETHYL)CYCLOHEXYL]METHANAMINE
    • CS-0439605
    • (1R,4R)-cyclohexane-1,4-diyldimethanamine
    • ((1R,4r)-cyclohexane-1,4-diyl)dimethanamine
    • BS-43837
    • SCHEMBL1703765
    • 1alpha,4alpha-Cyclohexanebis(methanamine)
    • MFCD20617651
    • DTXSID501302155
    • 4-Aminomethyl-cyclohexylmethyl-amine
    • [4-(Aminomethyl)cyclohexyl]methylamine, trans
    • CS-0128816
    • AKOS006342382
    • [4-(Aminomethyl)cyclohexyl]methylamine, (Z)-
    • [(1r,4r)-4-(aminomethyl)cyclohexyl]methanamine
    • p-Bis(aminomethyl)cyclohexane
    • trans-1, 4cyclohexane-bis(methylamine)
    • 1,4-Cyclohexanedimethylamine
    • cis-4-Aminomethylcyclohexylmethylamine
    • [4-(Aminomethyl)cyclohexyl]methylamine
    • DTXSID101298049
    • Cyclohexane-1alpha,4alpha-bis(methanamine)
    • NSC71997
    • SB30037
    • 1,4-Cyclohexanedimethanamine, trans-
    • SCHEMBL432248
    • T70002
    • 1,4-bis-(aminomethyl)-cyclohexane
    • cis-1,4-Cyclohexylenebis(methylamine)
    • trans-1,4-Cyclohexanebis(methylamine)
    • CS-0439581
    • BS-27717
    • [4-(Aminomethyl)cyclohexyl]methylamine #
    • 1,4-Cyclohexanebis(methylamine), trans-
    • AI3-26964
    • 2549-93-1
    • AKOS006342381
    • BP-30062
    • 1-[4-(aminomethyl)cyclohexyl]methanamine
    • Cyclohexane-1alpha,4beta-di(methaneamine)
    • AKOS009158487
    • 1,4-Cyclohexanebis(methylamine), cis + trans
    • 1alpha,4beta-Cyclohexanebis(methanamine)
    • B1083
    • B5147
    • ((1S,4s)-cyclohexane-1,4-diyl)dimethanamine
    • DB-058342
    • DB-046713
    • DB-264643
    • MDL： MFCD20037427
    • Inchi： 1S/C8H18N2/c9-5-7-1-2-8(6-10)4-3-7/h7-8H,1-6,9-10H2
    • InChI Key： OXIKYYJDTWKERT-UHFFFAOYSA-N
    • SMILES： NCC1CCC(CN)CC1

Computed Properties

  • Exact Mass: 142.14700
  • Monoisotopic Mass: 142.146999
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 73.3
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 52
  • XLogP3: 0.1

Experimental Properties

  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 118°C/10mmHg(lit.)
  • Flash Point: 119.7±20.4 °C
  • Refractive Index: 1.4870-1.4910
  • PSA: 52.04000
  • LogP: 2.11080
  • Vapor Pressure: 0.1±0.5 mmHg at 25°C

(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans Security Information

(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans Customs Data

  • HS CODE：2921300090
  • Customs Data：

    China Customs Code:

    2921300090

    Overview:

    2921300090 Other rings(Alkane,Alkene,Terpene)Monoamine or polyamine(Including its derivatives and their salts). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%

(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans Pricemore >>

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(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans Production Method

(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans Suppliers

Amadis Chemical Company Limited
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(CAS:10029-07-9)(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans
Order Number:A1011623
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 15:12
Price ($):176.0

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Additional information on (1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans

Professional Introduction to (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans and CAS No. 10029-07-9

The compound with the CAS number 10029-07-9 and the product name (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans represents a significant area of interest in the field of chemical and pharmaceutical research. This compound, characterized by its unique stereochemistry and structural properties, has garnered attention for its potential applications in drug development and biochemical studies.

In recent years, the exploration of chiral amines has been a cornerstone in the pharmaceutical industry due to their role in creating enantiomerically pure drugs. The stereochemistry of (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans is particularly noteworthy as it provides a versatile scaffold for designing molecules with specific biological activities. The trans configuration of this amine not only influences its physicochemical properties but also plays a crucial role in determining its interactions with biological targets.

Recent studies have highlighted the importance of understanding the three-dimensional structure of molecules in drug design. The cyclohexyl backbone in (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans contributes to its stability and flexibility, making it an attractive candidate for further derivatization. Researchers have been exploring various synthetic pathways to modify this compound, aiming to enhance its pharmacological properties.

The amine functional group at the 4-position of the cyclohexane ring is particularly interesting as it can be easily modified to introduce different substituents. This flexibility has led to several innovative approaches in drug discovery, where (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans serves as a key intermediate. For instance, recent advancements in catalytic amination techniques have enabled the efficient introduction of various amine derivatives, expanding the library of potential drug candidates.

The compound's unique structural features also make it a valuable tool in biochemical research. Its ability to interact with enzymes and receptors has been studied extensively, providing insights into molecular recognition processes. These studies are crucial for developing drugs that can selectively target specific biological pathways without off-target effects.

In addition to its pharmaceutical applications, (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans has shown promise in material science. Its chiral nature allows for the creation of novel materials with tailored properties, such as liquid crystals and polymers. These materials can be used in various industries, including electronics and optoelectronics.

The synthesis of enantiomerically pure compounds like (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans is often challenging due to the complexity of stereocontrol during organic reactions. However, recent developments in asymmetric synthesis have made significant strides in overcoming these challenges. Techniques such as chiral auxiliary-assisted reactions and transition metal-catalyzed asymmetric transformations have greatly improved the efficiency and scalability of producing such compounds.

The pharmacological potential of (1R,4R)-4-(aminomethyl)cyclohexylmethanamine, trans has also been explored in preclinical studies. Initial findings suggest that this compound may have therapeutic effects in several areas, including central nervous system disorders and inflammatory conditions. These preliminary results are encouraging and warrant further investigation into its mechanisms of action.

The future direction of research on this compound is likely to focus on optimizing its synthetic routes and exploring new derivatives. By leveraging advanced computational methods and high-throughput screening techniques, scientists can accelerate the discovery process and identify novel analogs with enhanced properties.

In conclusion, the compound CAS No. 10029-07-9 and its product name (1R,4R)-4-(aminomethyl)cyclohexylmethanamine(trans) represent a fascinating subject of study with broad implications in pharmaceuticals and material science. Its unique structural features and stereochemistry offer numerous opportunities for innovation and development.

10029-07-9 ((1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans) Related Products

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Amadis Chemical Company Limited
(CAS:10029-07-9)(1r,4r)-4-(aminomethyl)cyclohexylmethanamine, trans
A1011623
Purity:99%
Quantity:1g
Price ($):176.0
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