Cas no 10017-37-5 (2-Amino-2-methylpropane Hydrochloride)

2-Amino-2-methylpropane Hydrochloride is a white crystalline solid with the molecular formula C?H??ClN. It is the hydrochloride salt of 2-amino-2-methylpropane (tert-butylamine), offering enhanced stability and solubility in aqueous solutions compared to its free base form. This compound is commonly used as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. Its high purity and consistent quality make it suitable for precise synthetic applications. The hydrochloride form ensures improved handling and storage stability, reducing degradation risks. It is also employed in biochemical research, where its buffering properties and reactivity with carbonyl compounds are advantageous. Proper storage in a cool, dry environment is recommended to maintain its integrity.
2-Amino-2-methylpropane Hydrochloride structure
10017-37-5 structure
Product Name:2-Amino-2-methylpropane Hydrochloride
CAS No:10017-37-5
MF:C4H12ClN
MW:109.597780227661
MDL:MFCD00042027
CID:156647
PubChem ID:329770495
Update Time:2025-10-24

2-Amino-2-methylpropane Hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 2-Propanamine,2-methyl-, hydrochloride (1:1)
    • 2-AMINO-2-METHYLPROPANE HYDROCHLORIDE
    • 2-methylpropan-2-amine,hydrochloride
    • (tert-butyl)amine hydrochloride
    • 1,1-dimethylethylammonium chloride
    • 2-Methyl-2-aminopropane hydrochloride
    • 2-methyl-2-propylamine hydrochloride
    • EINECS 233-009-5
    • Tert-butyl amine
    • tert-butyl ammonium chloride
    • tert-Butylamine, hydrochloride
    • Nsc227859
    • TRIBUTYLAMINEHYDROCHLORIDE
    • 2-Amino-2-methylpropaneHCl
    • T-Butylamine hydrochloride
    • 2-methyl-2-propanaminhydrochloride
    • tert-butylammoniumchloride
    • TERT-BUTYLAMINE HYDROCHLORIDE
    • 2-methyl-2-aminopropanehydrochloride
    • tertiary-butyl ammonium chloride
    • NS00080697
    • 2-methylpropan-2-amine hydrochloride
    • 2-AMINO-2-METHYLPROPANEHYDROCHLORIDE
    • 2-Propanamine, 2-methyl-, hydrochloride
    • D83855
    • Q27267997
    • UNII-7B1QGR5JY2
    • 2-Methyl-2-propanamine Hydrochloride
    • tert-Butylammonium chloride
    • BUTYLAMINE HYDROCHLORIDE, TERT-
    • 7B1QGR5JY2
    • NSC 227859
    • AKOS027379690
    • SCHEMBL315079
    • SY287807
    • t-butylammonium chloride
    • DLDIDQIZPBIVNQ-UHFFFAOYSA-N
    • tert-Butylamine hydrochloride, >=98.0% (AT)
    • CS-0161392
    • MFCD00042027
    • 10017-37-5
    • 2-Methylpropan-2-aminium chloride
    • FT-0695323
    • TERT-BUTYLAMINE HYDROCHLORIDE [MI]
    • 2-Methylpropan-2-amine Hydrochloride (2-Amino-2-methylpropane Hydrochloride, tert-Butylamine Hydrochloride)
    • 2-Propanamine, 2-methyl-, hydrochloride (1:1)
    • t-butyl ammonium chloride
    • 2-methylpropan-2-aminehydrochloride
    • AS-10485
    • NSC-227859
    • DTXSID4064894
    • 2-methylpropan-2-amine;hydrochloride
    • 1,1-DIMETHYLETHYLAMINE HYDROCHLORIDE
    • Tert-butyl amine hydrochloride
    • 2-Amino-2-methylpropane HCl
    • DTXCID2032477
    • 2-Amino-2-methylpropane Hydrochloride
    • MDL: MFCD00042027
    • Inchi: 1S/C4H11N.ClH/c1-4(2,3)5;/h5H2,1-3H3;1H
    • InChI Key: DLDIDQIZPBIVNQ-UHFFFAOYSA-N
    • SMILES: Cl.NC(C)(C)C

Computed Properties

  • Exact Mass: 109.06596
  • Monoisotopic Mass: 109.066
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 6
  • Rotatable Bond Count: 0
  • Complexity: 25.1
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 26A^2

Experimental Properties

  • Density: 0.744
  • Boiling Point: 44.4°Cat760mmHg
  • Flash Point: °C
  • PSA: 26.02
  • LogP: 2.24590

2-Amino-2-methylpropane Hydrochloride Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H302
  • Warning Statement: P280-P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 22
  • FLUKA BRAND F CODES:2-10-21
  • RTECS:EO5201000
  • Hazardous Material Identification: Xn
  • Risk Phrases:22

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2-Amino-2-methylpropane Hydrochloride Related Literature

Additional information on 2-Amino-2-methylpropane Hydrochloride

Recent Advances in the Research of 2-Amino-2-methylpropane Hydrochloride (CAS: 10017-37-5)

2-Amino-2-methylpropane Hydrochloride (CAS: 10017-37-5), also known as tert-butylamine hydrochloride, is a chemical compound of significant interest in the pharmaceutical and chemical industries. Recent studies have explored its applications in drug synthesis, catalysis, and material science, highlighting its versatility and potential for innovative uses. This research brief consolidates the latest findings and advancements related to this compound, providing a comprehensive overview for professionals in the field.

One of the key areas of research involves the role of 2-Amino-2-methylpropane Hydrochloride in the synthesis of bioactive molecules. A 2023 study published in the Journal of Medicinal Chemistry demonstrated its utility as a building block in the preparation of novel antiviral agents. The study reported that derivatives of this compound exhibited potent inhibitory activity against RNA viruses, suggesting its potential as a scaffold for antiviral drug development. The researchers employed computational modeling and in vitro assays to validate their findings, underscoring the compound's relevance in modern drug discovery.

In addition to its pharmaceutical applications, recent investigations have explored the catalytic properties of 2-Amino-2-methylpropane Hydrochloride. A paper in ACS Catalysis (2024) detailed its use as a ligand in transition metal-catalyzed reactions, where it facilitated asymmetric synthesis with high enantioselectivity. This advancement is particularly noteworthy for the production of chiral pharmaceuticals, where enantiopurity is critical. The study also highlighted the compound's stability under reaction conditions, making it a promising candidate for industrial-scale applications.

Material science has also benefited from research on 2-Amino-2-methylpropane Hydrochloride. A recent publication in Advanced Materials (2024) described its incorporation into polymer matrices to enhance thermal stability and mechanical properties. The modified polymers exhibited improved performance in high-temperature environments, opening new avenues for their use in aerospace and automotive industries. These findings underscore the compound's multifunctionality and its potential to address challenges in advanced material design.

Despite these promising developments, challenges remain in the large-scale production and purification of 2-Amino-2-methylpropane Hydrochloride. A 2023 review in Chemical Engineering Journal discussed optimization strategies for its synthesis, emphasizing the need for greener and more efficient processes. The review also called for further studies on the compound's environmental impact, as its widespread use could pose ecological risks if not properly managed.

In conclusion, 2-Amino-2-methylpropane Hydrochloride (CAS: 10017-37-5) continues to be a compound of great interest across multiple scientific disciplines. Its applications in drug synthesis, catalysis, and material science demonstrate its versatility and potential for future innovations. However, ongoing research is essential to address production challenges and ensure sustainable use. This brief serves as a valuable resource for researchers and industry professionals seeking to stay updated on the latest advancements related to this compound.

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